Search Results - "Gowrisankaran, Sindhuja"
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Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin
Published in Nature communications (09-03-2020)“…Endophilins-A are conserved endocytic adaptors with membrane curvature-sensing and -inducing properties. We show here that, independently of their role in…”
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Endophilin-A Deficiency Induces the Foxo3a-Fbxo32 Network in the Brain and Causes Dysregulation of Autophagy and the Ubiquitin-Proteasome System
Published in Cell reports (Cambridge) (18-10-2016)“…Endophilin-A, a well-characterized endocytic adaptor essential for synaptic vesicle recycling, has recently been linked to neurodegeneration. We report here…”
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Cells Control BIN1-Mediated Membrane Tubulation by Altering the Membrane Charge
Published in Journal of molecular biology (14-02-2020)“…The Bridging integrator 1 (BIN1)/Amphiphysin/Rvs (BAR) protein family is an essential part of the cell's machinery to bend membranes. BIN1 is a muscle-enriched…”
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Clathrin coat controls synaptic vesicle acidification by blocking vacuolar ATPase activity
Published in eLife (13-04-2018)“…Newly-formed synaptic vesicles (SVs) are rapidly acidified by vacuolar adenosine triphosphatases (vATPases), generating a proton electrochemical gradient that…”
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The Cancer Genome Atlas Analysis Predicts MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma
Published in Molecular therapy (01-07-2015)“…Using in silico analysis of The Cancer Genome Atlas (TCGA), we identified microRNAs associated with glioblastoma (GBM) survival, and predicted their functions…”
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Regulation of synaptic vesicle acidification at the neuronal synapse
Published in IUBMB life (01-04-2020)“…The vacuolar H+‐adenosine triphosphatases (vATPases) acidify multiple intracellular organelles, including synaptic vesicles (SVs) and secretory granules…”
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Clathrin Coat Controls Vesicle Acidification by Blocking Vacuolar ATPase Activity
Published in Biophysical journal (02-02-2018)Get full text
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