Search Results - "Gowrisankar Rajam"

Genetic Meningococcal Antigen Typing System (gMATS): A genotyping tool that predicts 4CMenB strain coverage worldwide by Muzzi, Alessandro, Brozzi, Alessandro, Serino, Laura, Bodini, Margherita, Abad, Raquel, Caugant, Dominique, Comanducci, Maurizio, Lemos, Ana Paula, Gorla, Maria Cecilia, Křížová, Pavla, Mikula, Claudia, Mulhall, Robert, Nissen, Michael, Nohynek, Hanna, Simões, Maria João, Skoczyńska, Anna, Stefanelli, Paola, Taha, Muhamed-Kheir, Toropainen, Maija, Tzanakaki, Georgina, Vadivelu-Pechai, Kumaran, Watson, Philip, Vazquez, Julio A., Rajam, Gowrisankar, Rappuoli, Rino, Borrow, Ray, Medini, Duccio

“…The Meningococcal Antigen Typing System (MATS) was developed to identify meningococcus group B strains with a high likelihood of being covered by the 4CMenB…”
Get full text

Kinetics of maternal pertussis-specific antibodies in infants of mothers vaccinated with tetanus, diphtheria and acellular pertussis (Tdap) during pregnancy by Healy, C. Mary, Rench, Marcia A., Swaim, Laurie S., Timmins, Audra, Vyas, Anuja, Sangi-Haghpeykar, Haleh, Ng, Nancy, Rajam, Gowrisankar, Havers, Fiona, Schiffer, Jarad, Baker, Carol J.

“…•Half-life of pertussis antibodies in neonates after maternal Tdap vaccination is ∼29–36 days.•There is substantial individual variability in pertussis…”
Get full text

Streptococcus mitis Expressing Pneumococcal Serotype 1 Capsule by Lessa, Fernanda C., Milucky, Jennifer, Rouphael, Nadine G., Bennett, Nancy M., Talbot, H. Keipp, Harrison, Lee H., Farley, Monica M., Walston, Jeremy, Pimenta, Fabiana, Gertz, Robert E., Rajam, Gowrisankar, Carvalho, Maria da Gloria, Beall, Bernard, Whitney, Cynthia G.

“…Streptococcus pneumoniae’s polysaccharide capsule is an important virulence factor; vaccine-induced immunity to specific capsular polysaccharide effectively…”
Get full text

Diagnosis of Streptococcus pneumoniae infection using circulating antibody secreting cells by Kyu, Shuya, Ramonell, Richard P, Kuruvilla, Merin, Kraft, Colleen S, Wang, Yun F, Falsey, Ann R, Walsh, Edward E, Daiss, John L, Paulos, Simon, Rajam, Gowrisankar, Wu, Hao, Velusamy, Srinivasan, Lee, F Eun-Hyung

“…Streptococcus pneumoniae infections cause morbidity and mortality worldwide. A rapid, simple diagnostic method could reduce the time needed to introduce…”
Get full text

Late effects of total body irradiation on hematopoietic recovery and immune function in rhesus macaques by Hale, Laura P, Rajam, Gowrisankar, Carlone, George M, Jiang, Chen, Owzar, Kouros, Dugan, Greg, Caudell, David, Chao, Nelson, Cline, J Mark, Register, Thomas C, Sempowski, Gregory D

“…While exposure to radiation can be lifesaving in certain settings, it can also potentially result in long-lasting adverse effects, particularly to…”
Get full text

Impact of maternally derived pertussis antibody titers on infant whole-cell pertussis vaccine response in a low income setting by Ibrahim, Romesa, Ali, S. Asad, Kazi, A. Momin, Rizvi, Arjumand, Guterman, L. Beryl, Bednarczyk, Robert A., Kim, Ellie, Park, SoHee, Paulos, Simon, Jeyachandran, Amilia, Patel, Divya, Gorantla, Yamini, Wong, Emily, Rajam, Gowrisankar, Schiffer, Jarad, Omer, Saad B.

“…Maternal vaccines against pertussis are not yet recommended in the developing world. Besides unclear burden estimates, another concern is that transplacental…”
Get full text

Development and Validation of a Sensitive and Robust Multiplex Antigen Capture Assay to Quantify Streptococcus pneumoniae Serotype-Specific Capsular Polysaccharides in Urine by Rajam, Gowrisankar, Zhang, Yuhua, Antonello, Joseph M., Grant-Klein, Rebecca J., Cook, Lauren, Panemangalore, Reshma, Pham, Huy, Cooper, Stephanie, Steinmetz, Thomas D., Nguyen, Jennifer, Pletz, Mathias W., Barten-Neiner, Grit, Murphy, Rocio D., Rubinstein, Leonard J., Nolan, Katrina M.

“…Streptococcus pneumoniae is a major cause of community-acquired pneumonia (CAP) in young children, older adults, and those with immunocompromised status. Since…”
Get full text

Streptococcus infantis, Streptococcus mitis , and Streptococcus oralis Strains With Highly Similar cps5 Loci and Antigenic Relatedness to Serotype 5 Pneumococci by Pimenta, Fabiana, Gertz, Jr, Robert E, Park, So Hee, Kim, Ellie, Moura, Iaci, Milucky, Jennifer, Rouphael, Nadine, Farley, Monica M, Harrison, Lee H, Bennett, Nancy M, Bigogo, Godfrey, Feikin, Daniel R, Breiman, Robert, Lessa, Fernanda C, Whitney, Cynthia G, Rajam, Gowrisankar, Schiffer, Jarad, da Gloria Carvalho, Maria, Beall, Bernard

“…is a highly impactful bacterial pathogen on a global scale. The principal pneumococcal virulence factor and target of effective vaccines is its polysaccharide…”
Get full text

Meningococcal Antigen Typing System (MATS)-Based Neisseria meningitidis Serogroup B Coverage Prediction for the MenB-4C Vaccine in the United States by Rajam, Gowrisankar, Stella, Maria, Kim, Ellie, Paulos, Simon, Boccadifuoco, Giuseppe, Serino, Laura, Carlone, George, Medini, Duccio

“…is the most common cause of bacterial meningitis in children and young adults worldwide. A 4-component vaccine against serogroup B (MenB) disease (MenB-4C…”
Get full text

Interlaboratory Standardization of the Sandwich Enzyme-Linked Immunosorbent Assay Designed for MATS, a Rapid, Reproducible Method for Estimating the Strain Coverage of Investigational Vaccines by Plikaytis, Brian D, Stella, Maria, Boccadifuoco, Giuseppe, DeTora, Lisa M, Agnusdei, Mauro, Santini, Laura, Brunelli, Brunella, Orlandi, Luca, Simmini, Isabella, Giuliani, Marzia, Ledroit, Morgan, Hong, Eva, Taha, Muhamed-Kheir, Ellie, Kim, Rajam, Gowrisankar, Carlone, George M, Claus, Heike, Vogel, Ulrich, Borrow, Ray, Findlow, Jamie, Gilchrist, Stefanie, Stefanelli, Paola, Fazio, Cecilia, Carannante, Anna, Oksnes, Jan, Fritzsønn, Elisabeth, Klem, Anne-Marie, Caugant, Dominique A, Abad, Raquel, Vázquez, Julio A, Rappuoli, Rino, Pizza, Mariagrazia, Donnelly, John J, Medini, Duccio

“…OA  Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Effect of maternal Tdap on infant antibody response to a primary vaccination series with whole cell pertussis vaccine in São Paulo, Brazil by Vaz-de-Lima, Lourdes R.A., Sato, Ana Paula S., Pawloski, Lucia C., Fernandes, Eder G., Rajam, Gowrisankar, Sato, Helena K., Patel, Divya, Li, Han, de Castilho, Euclides A., Tondella, Maria Lucia, Schiffer, Jarad

“…•High antibody levels obtained from maternal Tdap might protect infants until 2 months.•Reduced anti-PT IgG at 7 months of age indicate potential blunting of…”
Get full text

Immunoactivating Peptide P4 Augments Alveolar Macrophage Phagocytosis in Two Diverse Human Populations by BANGERT, Mathieu, WRIGHT, Adam K, GORDON, Stephen B, RYLANCE, Jamie, KELLY, Matthew J, WRIGHT, Angela D, CARLONE, George M, SAMPSON, Jacquelyn S, RAJAM, Gowrisankar, ADES, Edwin W, KADIOGLU, Aras

“…OA  Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Erratum for Rajam et al., "Meningococcal Antigen Typing System (MATS)-Based Neisseria meningitidis Serogroup B Coverage Prediction for the MenB-4C Vaccine in the United States" by Rajam, Gowrisankar, Stella, Maria, Kim, Ellie, Paulos, Simon, Boccadifuoco, Giuseppe, Serino, Laura, Carlone, George, Medini, Duccio

Get full text

Immunotherapy with a Combination of Intravenous Immune Globulin and P4 Peptide Rescues Mice from Postinfluenza Pneumococcal Pneumonia by WEEKS, Jenni N, BOYD, Kelli L, RAJAM, Gowrisankar, ADES, Edwin W, MCCULLERS, Jonathan A

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

E-cadherin is a receptor for the common protein pneumococcal surface adhesin A (PsaA) of Streptococcus pneumoniae by Anderton, Julie M., Rajam, Gowrisankar, Romero-Steiner, Sandra, Summer, Susan, Kowalczyk, Andrew P., Carlone, George M., Sampson, Jacquelyn S., Ades, Edwin W.

“…Streptococcus pneumoniae (Pnc) binds to nasopharyngeal (NP) epithelial cells in the first steps of nasopharyngeal carriage and colonization through bacterial…”
Get full text

Functional Antibodies to the O-Acetylated Pneumococcal Serotype 15B Capsular Polysaccharide Have Low Cross-Reactivities with Serotype 15C by Rajam, Gowrisankar, Carlone, George M., Romero-Steiner, Sandra

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Evaluation of a Novel Therapeutic Approach to Treating Severe Pneumococcal Infection Using a Mouse Model by Melnick, Nikkol, Rajam, Gowrisankar, Carlone, George M, Sampson, Jacquelyn S, Ades, Edwin W

“…ERRATUM ( vol. 16 , p. 1093 ) Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg…”
Get full text

A functional epitope of the pneumococcal surface adhesin A activates nasopharyngeal cells and increases bacterial internalization by Rajam, Gowrisankar, Phillips, Donald J., White, Elizabeth, Anderton, Julie, Hooper, Craig W., Sampson, Jacquelyn S., Carlone, George M., Ades, Edwin W., Romero-Steiner, Sandra

“…Pneumococcal surface adhesin A (PsaA) is a putative pneumococcal (Pnc) adhesin known to bind to nasopharyngeal (NP) epithelial cells. This study evaluated the…”
Get full text

A Novel Innate Immune-Enhancement Strategy Combined with IVIG Rescues Mice from Fatal Staphylococcus aureus Septicemia by Rajam, Gowrisankar, Hammons, Gabrielle M., Carlone, George M., Sampson, Jacquelyn S., Ades, Edwin W.

“…Staphylococcus aureus (SA) is a major community-acquired pathogen. The emergence of drug-resistant strains like, methicillin-resistant SA (MRSA), poses stiff…”
Get full text

Adherence of nontypeable Streptococcus pneumoniae to human conjunctival epithelial cells by Williamson, Yulanda M., Gowrisankar, Rajam, Longo, Dana L., Facklam, Richard, Gipson, Ilene K., Ades, Edwin P., Carlone, George M., Sampson, Jacquelyn S.

“…Conjunctivitis outbreaks have occurred in the US in which nontypeable (NT) Streptococcus pneumoniae (Pnc) strains have been identified as the etiologic agent;…”
Get full text