Search Results - "Gowers, D M"

Protein motion from non-specific to specific DNA by three-dimensional routes aided by supercoiling by Gowers, Darren M., Halford, Stephen E.

“…DNA‐binding proteins are generally thought to locate their target sites by first associating with the DNA at random and then translocating to the specific site…”
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DNA Triple Helix Formation at Oligopurine Sites Containing Multiple Contiguous Pyrimidines by Gowers, Darren M., Fox, Keith R.

“…We have used DNase I footprinting to assess the formation of triple helices at 15mer oligopurine target sites which are interrupted by several (up to four)…”
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Towards mixed sequence recognition by triple helix formation by Gowers, Darren M., Fox, Keith R.

“…The formation of intermolecular DNA triple helices offers the possibility of designing compounds with extensive sequence recognition properties which may be…”
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Restriction endonuclease reactions requiring two recognition sites by Halford, S E, Bilcock, D T, Stanford, N P, Williams, S A, Milsom, S E, Gormley, N A, Watson, M A, Bath, A J, Embleton, M L, Gowers, D M, Daniels, L E, Parry, S H, Szczelkun, M D

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One recognition sequence, seven restriction enzymes, five reaction mechanisms by Gowers, Darren M., Bellamy, Stuart R.W., Halford, Stephen E.

“…The diversity of reaction mechanisms employed by Type II restriction enzymes was investigated by analysing the reactions of seven endonucleases at the same DNA…”
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Alternative geometries of DNA looping: an analysis using the SfiI endonuclease by Watson, Mark A, Gowers, Darren M, Halford, Stephen E

“…Many processes are governed by proteins that bind to separate sites in DNA and loop out the intervening DNA, but the geometries of the loops have seldom been…”
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Two are better than one by Halford, Stephen E, Gowers, Darren M, Sessions, Richard B

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DNA Triple Helix Formation at Target Sites Containing Several Pyrimidine Interruptions:  Stabilization by Protonated Cytosine or 5-(1-Propargylamino)dU by Gowers, Darren M, Bijapur, Jeevan, Brown, Tom, Fox, Keith R

“…DNase I footprinting has been used to study the formation of parallel triplexes at oligopurine target sequences which are interrupted by pyrimidines at regular…”
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Triple helix formation at (AT)n adjacent to an oligopurine tract by Gowers, Darren M., Fox, Keith R.

“…We have used DNase I footprinting to investigate the recognition of (AT)n tracts in duplex DNA using GT-containing oligonucleotides designed to form…”
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Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS by Henderson, Charlotte A, Vincent, Helen A, Casamento, Alessandra, Stone, Carlanne M, Phillips, Jack O, Cary, Peter D, Sobott, Frank, Gowers, Darren M, Taylor, James E N, Callaghan, Anastasia J

“…OxyS and RprA are two small noncoding RNAs (sRNAs) that modulate the expression of rpoS, encoding an alternative sigma factor that activates transcription of…”
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Restriction Endonucleases that Bridge and Excise Two Recognition Sites from DNA by Marshall, Jacqueline J.T., Gowers, Darren M., Halford, Stephen E.

“…Most restriction endonucleases bridge two target sites before cleaving DNA: examples include all of the translocating Type I and Type III systems, and many…”
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Measurement of the Contributions of 1D and 3D Pathways to the Translocation of a Protein along DNA by Darren M. Gowers, Geoffrey G. Wilson, Halford, Stephen E., von Hippel, Peter H.

“…Proteins that act at specific DNA sequences bind DNA randomly and then translocate to the target site. The translocation is often ascribed to the protein…”
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Triple helix formation at (AT) sub(n) adjacent to an oligopurine tract by Gowers, D M, Fox, K R

“…We have used DNase I footprinting to investigate the recognition of (AT) sub(n) tracts in duplex DNA using GT-containing oligonucleotides designed to form…”
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Alternative Geometries of DNA Looping: an Analysis using the Sfi I Endonuclease by Watson, MA, Gowers, D M, Halford, SE

“…Many processes are governed by proteins that bind to separate sites in DNA and loop out the intervening DNA, but the geometries of the loops have seldom been…”
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DNA triple helix formation at (AT)n tracts by Gowers, D M, Fox, K R

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