Search Results - "Gower, Nicholas J"

New ligands for nickel catalysis from diverse pharmaceutical heterocycle libraries by Hansen, Eric C., Pedro, Dylan J., Wotal, Alexander C., Gower, Nicholas J., Nelson, Jade D., Caron, Stephane, Weix, Daniel J.

“…Ligands are essential for controlling the reactivity and selectivity of reactions catalysed by transition metals. Access to large phosphine ligand libraries…”
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Simplifying Iron-Phosphine Catalysts for Cross-Coupling Reactions by Bedford, Robin B., Carter, Emma, Cogswell, Paul M., Gower, Nicholas J., Haddow, Mairi F., Harvey, Jeremy N., Murphy, Damien M., Neeve, Emily C., Nunn, Joshua

“…Any old iron? Iron catalysts based on the widely available diphosphine ligand bis(diphenylphosphino)ethane have not previously fared particularly well in…”
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Investigation of Organoiron Catalysis in Kumada–Tamao–Corriu-Type Cross-Coupling Reaction Assisted by Solution-Phase X-ray Absorption Spectroscopy by Takaya, Hikaru, Nakajima, Sho, Nakagawa, Naohisa, Isozaki, Katsuhiro, Iwamoto, Takahiro, Imayoshi, Ryuji, Gower, Nicholas J, Adak, Laksmikanta, Hatakeyama, Takuji, Honma, Tetsuo, Takagaki, Masafumi, Sunada, Yusuke, Nagashima, Hideo, Hashizume, Daisuke, Takahashi, Osamu, Nakamura, Masaharu

“…Solution-phase synchrotron X-ray absorption spectroscopy (XAS) is a powerful tool for structural and mechanistic investigations of paramagnetic organoiron…”
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Drug discovery in ophthalmology: past success, present challenges, and future opportunities by Gower, Nicholas J D, Barry, Robert J, Edmunds, Matthew R, Titcomb, Lucy C, Denniston, Alastair K

“…Drug discovery has undergone major transformations in the last century, progressing from the recognition and refinement of natural products with therapeutic…”
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Exploiting Boron-Zinc Transmetallation for the Arylation of Benzyl Halides: What are the Reactive Species? by Bedford, Robin B., Gower, Nicholas J., Haddow, Mairi F., Harvey, Jeremy N., Nunn, Joshua, Okopie, Rukeme A., Sankey, Rosalind F.

“…One step Beyond: The transmetallation reactions of ArB(OH)2 and Ar3B3O3 with Et2Zn are far more complicated than previously supposed, with solvent‐dependent…”
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Inositol 1,4,5-trisphosphate signalling regulates the avoidance response to nose touch in Caenorhabditis elegans by Walker, Denise S, Vázquez-Manrique, Rafael P, Gower, Nicholas J D, Gregory, Elizabeth, Schafer, William R, Baylis, Howard A

“…When Caenorhabditis elegans encounters an unfavourable stimulus at its anterior, it responds by initiating an avoidance response, namely reversal of…”
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Nickel-Catalyzed Cross-Electrophile Coupling with Organic Reductants in Non-Amide Solvents by Anka-Lufford, Lukiana L., Huihui, Kierra M. M., Gower, Nicholas J., Ackerman, Laura K. G., Weix, Daniel J.

“…Cross‐electrophile coupling of aryl halides with alkyl halides has thus far been primarily conducted with stoichiometric metallic reductants in amide solvents…”
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Iron(I) in Negishi Cross-Coupling Reactions by Adams, Christopher J, Bedford, Robin B, Carter, Emma, Gower, Nicholas J, Haddow, Mairi F, Harvey, Jeremy N, Huwe, Michael, Cartes, M. Ángeles, Mansell, Stephen M, Mendoza, Carla, Murphy, Damien M, Neeve, Emily C, Nunn, Joshua

“…Herein we demonstrate both the importance of Fe­(I) in Negishi cross-coupling reactions with arylzinc reagents and the isolation of catalytically competent…”
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Inositol 1,4,5-trisphosphate signaling regulates mating behavior in Caenorhabditis elegans males by Gower, Nicholas J D, Walker, Denise S, Baylis, Howard A

“…Complex behavior requires the coordinated action of the nervous system and nonneuronal targets. Male mating in Caenorhabditis elegans consists of a series of…”
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Iron Phosphine Catalyzed Cross-Coupling of Tetraorganoborates and Related Group 13 Nucleophiles with Alkyl Halides by Bedford, Robin B, Brenner, Peter B, Carter, Emma, Clifton, Jamie, Cogswell, Paul M, Gower, Nicholas J, Haddow, Mairi F, Harvey, Jeremy N, Kehl, Jeffrey A, Murphy, Damien M, Neeve, Emily C, Neidig, Michael L, Nunn, Joshua, Snyder, Benjamin E. R, Taylor, Joseph

“…Iron phosphine complexes prove to be good precatalysts for the cross-coupling of alkyl, benzyl, and allyl halides with not only aryl triorganoborate salts but…”
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Inositol 1,4,5-trisphosphate signaling regulates rhythmic contractile activity of myoepithelial sheath cells in Caenorhabditis elegans by Yin, Xiaoyan, Gower, Nicholas J D, Baylis, Howard A, Strange, Kevin

“…Intercellular communication between germ cells and neighboring somatic cells is essential for reproduction. Caenorhabditis elegans oocytes are surrounded by…”
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IRI-1, a LIN-15B homologue, interacts with inositol-1,4,5-triphosphate receptors and regulates gonadogenesis, defecation, and pharyngeal pumping in Caenorhabditis elegans by Walker, Denise S, Ly, Sung, Gower, Nicholas J D, Baylis, Howard A

“…Inositol-1,4,5-triphosphate receptors (IP(3)Rs) are ligand-gated Ca(2+) channels that control Ca(2+) release from intracellular stores. They are central to a…”
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Exploiting Boron–Zinc Transmetallation for the Arylation of Benzyl Halides: What are the Reactive Species? by Bedford, Robin B., Gower, Nicholas J., Haddow, Mairi F., Harvey, Jeremy N., Nunn, Joshua, Okopie, Rukeme A., Sankey, Rosalind F.

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Simplifying Iron–Phosphine Catalysts for Cross‐Coupling Reactions by Bedford, Robin B., Carter, Emma, Cogswell, Paul M., Gower, Nicholas J., Haddow, Mairi F., Harvey, Jeremy N., Murphy, Damien M., Neeve, Emily C., Nunn, Joshua

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Iron-catalysed Suzuki coupling? A cautionary tale by Bedford, Robin B., Nakamura, Masaharu, Gower, Nicholas J., Haddow, Mairi F., Hall, Mark A., Huwe, Michael, Hashimoto, Tohru, Okopie, Rukeme A.

“…During an investigation on a reported iron-catalysed Suzuki reaction, we uncovered how little palladium contamination is required to generate positive results…”
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Inositol 1,4,5-Trisphosphate Signaling Regulates Mating Behavior in Caenorhabditis elegans MalesD by Gower, Nicholas J. D., Walker, Denise S., Baylis, Howard A.

“…Complex behavior requires the coordinated action of the nervous system and nonneuronal targets. Male mating in Caenorhabditis elegans consists of a series of…”
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Regulated disruption of inositol 1,4,5-trisphosphate signaling in Caenorhabditis elegans reveals new functions in feeding and embryogenesis by Walker, Denise S, Gower, Nicholas J D, Ly, Sung, Bradley, Gemma L, Baylis, Howard A

“…Inositol 1,4,5-trisphosphate (IP(3)) is an important second messenger in animal cells and is central to a wide range of cellular responses. The major…”
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Exploiting Boron-Zinc Transmetallation for the Arylation of Benzyl Halides: What are the Reactive Species? by Bedford, Robin B., Gower, Nicholas J., Haddow, Mairi F., Harvey, Jeremy N., Nunn, Joshua, Okopie, Rukeme A., Sankey, Rosalind F.

“…Einen Schritt weiter: Die Transmetallierungen von ArB(OH)2 und Ar3B3O3 mit Et2Zn sind komplizierter als bisher angenommen, da lösungsmittelabhängige…”
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Simplifying Iron-Phosphine Catalysts for Cross-Coupling Reactions by Bedford, Robin B., Carter, Emma, Cogswell, Paul M., Gower, Nicholas J., Haddow, Mairi F., Harvey, Jeremy N., Murphy, Damien M., Neeve, Emily C., Nunn, Joshua

“…Man braucht nur den richtigen Bis(s)! Eisenkatalysatoren auf Basis des leicht zugänglichen Liganden Bis(diphenylphosphanyl)ethan waren früher wenig erfolgreich…”
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Inositol 1,4,5-Trisphosphate Signalling Regulates the Avoidance Response to Nose Touch in Caenorhabditis elegans: e1000636 by Walker, Denise S, Vázquez-Manrique, Rafael P, Gower, Nicholas JD, Gregory, Elizabeth, Schafer, William R, Baylis, Howard A

“…When Caenorhabditis elegans encounters an unfavourable stimulus at its anterior, it responds by initiating an avoidance response, namely reversal of…”
Get full text