Search Results - "Gower, N."

Impact of the ABCD‐GENE Score on Clopidogrel Clinical Effectiveness after PCI: A Multi‐Site, Real‐World Investigation by Thomas, Cameron D., Franchi, Francesco, Keeley, Ellen C., Rossi, Joseph S., Winget, Marshall, David Anderson, R., Dempsey, Alyssa L., Gong, Yan, Gower, Megan N., Kerensky, Richard A., Kulick, Natasha, Malave, Jean G., McDonough, Caitrin W., Mulrenin, Ian R., Starostik, Petr, Beitelshees, Amber L., Johnson, Julie A., Stouffer, George A., Winterstein, Almut G., Angiolillo, Dominick J., Lee, Craig R., Cavallari, Larisa H.

“…The Age, Body mass index, Chronic kidney disease, Diabetes mellitus, and CYP2C19 GENEtic variants (ABCD‐GENE) score was developed to identify patients at risk…”
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Chemotherapy versus supportive care in advanced non-small cell lung cancer: improved survival without detriment to quality of life by Spiro, S G, Rudd, R M, Souhami, R L, Brown, J, Fairlamb, D J, Gower, N H, Maslove, L, Milroy, R, Napp, V, Parmar, M K B, Peake, M D, Stephens, R J, Thorpe, H, Waller, D A, West, P

“…Background: In 1995 a meta-analysis of randomised trials investigating the value of adding chemotherapy to primary treatment for non-small cell lung cancer…”
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Chemotherapy for patients with non-small cell lung cancer: the surgical setting of the Big Lung Trial by Waller, D., Peake, M.D., Stephens, R.J., Gower, N.H., Milroy, R., Parmar, M.K.B., Rudd, R.M., Spiro, S.G.

“…Objectives: The non-small cell lung cancer (NSCLC) meta-analysis suggested a survival benefit for cisplatin-based chemotherapy when given in addition to…”
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Mitomycin, Ifosfamide, and Cisplatin in Unresectable Non–Small-Cell Lung Cancer: Effects on Survival and Quality of Life by CULLEN, M. H, BILLINGHAM, L. J, TRASK, C, BESSELL, E, CONNOLLY, C. K, TOBIAS, J, SOUHAMI, R. L, WOODROFFE, C. M, CHETIYAWARDANA, A. D, GOWER, N. H, JOSHI, R, FERRY, D. R, RUDD, R. M, SPIRO, S. G, COOK, J. E

“…Chemotherapy for non-small-cell lung cancer (NSCLC) remains controversial. We describe the two largest reported, randomized, parallel trials designed to…”
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Comparative analyses between younger and older patients with pancreatic adenocarcinoma: differences in clinicopathological features, treatment patterns, and outcomes by Salem, M., Kadakia, K., Trufan, S., Hwang, J., Nazemzadeh, R., Jagosky, M., Worrilow, W., Coley, H., Al Hallak, M., Gower, N., Philip, P., O’Reilly, E.

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Study of the efficacy of novel bispecific antibodies targeting immune checkpoints in a 3D model of B non‐Hodgkin lymphoma by Gower, N., Gava, F., Rimailho, L., Faria, C., Gravelle, P., Perez‐Galan, P., Serrat, N., Bouquet, F., Fonseca, C., Herter, S., Codarri, L., McCord, R., Chiang, E., Morschhauser, F., Ysebaert, L., Laurent, C., Bezombes, C.

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TAyloring LYmphoma therapy with Immune Escape Signatures from 3D avatars of B‐cell NHL by Gava, F., Faria, C., Gravelle, P., Garcia‐Valero, J., Quelen, C., Serrat, N., Gower, N., Morschhauser, F., Fournié, J., Bouquet, F., Fonseca, C., Herter, S., Codarri, L., McCord, R., Chiang, E., Laurent, C., Perez‐Galan, P., Ysebaert, L., Bezombes, C.

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Assessment of Quality of Life in the Supportive Care Setting of the Big Lung Trial in Non–Small-Cell Lung Cancer by BROWN, J, THORPE, H, WALLER, D, WEST, P, PEAKE, M. D, NAPP, V, FAIRLAMB, D. J, GOWER, N. H, MILROY, R, PARMAR, M. K. B, RUDD, R. M, SPIRO, S. G, STEPHENS, R. J

“…The Big Lung Trial (BLT) was a large, pragmatic trial to evaluate the addition of chemotherapy to primary treatment (ie, surgery, radical radiotherapy, or…”
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Clinical Utility of CYP2C19 Genotype-Guided Antiplatelet Therapy in Patients at Risk of Adverse Cardiovascular and Cerebrovascular Events: A Review of Emerging Evidence by Gower, Megan N, Ratner, Lindsay R, Williams, Alexis K, Rossi, Joseph S, Stouffer, George A, Lee, Craig R

“…In patients undergoing percutaneous coronary intervention (PCI), the standard of care is dual antiplatelet therapy with a P2Y 12 inhibitor (clopidogrel,…”
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Comparison of gemcitabine and carboplatin versus cisplatin and etoposide for patients with poor-prognosis small cell lung cancer by Lee, S M, James, L E, Qian, W, Spiro, S, Eisen, T, Gower, N H, Ferry, D R, Gilligan, D, Harper, P G, Prendiville, J, Hocking, M, Rudd, R M

“…The combination of cisplatin and etoposide (PE) has been a standard treatment for patients with poor-prognosis small cell lung cancer (SCLC). This…”
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Echinococcus multilocularis on Svalbard: introduction of an intermediate host has enabled the local life-cycle by Henttonen, H, Fuglei, E, Gower, C N, Haukisalmi, V, Ims, R A, Niemimaa, J, Yoccoz, N G

“…The taeniid tapeworm Echinococcus multilocularis is here reported for the first time at the Svalbard Archipelago in the Norwegian Arctic. This new finding is…”
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Five-day oral etoposide treatment for advanced small-cell lung cancer : Randomized comparison with intravenous chemotherapy by SOUHAMI, R. L, SPIRO, S. G, RUDD, R. M, RUIZ DE ELVIRA, M.-C, JAMES, L. E, GOWER, N. H, LAMONT, A, HARPER, P. G

“…Oral etoposide is an active single agent in small-cell lung cancer (SCLC) and is widely prescribed as first-line treatment as an alternative to intravenous…”
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Phase II trial of vinorelbine and oxaliplatin as first-line therapy in malignant pleural mesothelioma by Fennell, Dean A., C. Steele, Jeremy P., Shamash, Jonathan, Sheaff, Michael T., Evans, Marie T., Goonewardene, Tyronne I, Nystrom, Maria L., Gower, N.H., Rudd, Robin M.

“…The incidence of malignant pleural mesothelioma (MPM) is increasing. Treatment options are limited, although recently published data have offered cause for…”
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Characterizing diurnal roosts of male Little Brown Myotis (Myotis lucifugus) during summer by Hilty, Shannon L., Litt, Andrea R., Maxell, Bryce A., Gower, Claire N., Garrott, Robert A., Hanauska-Brown, Lauri

“…Shelter is one critical aspect of an animal's habitat, providing refuge from predators and weather, protection for offspring, and aiding in physiological…”
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Habitat conditions at beaver settlement sites: implications for beaver restoration projects by Ritter, Torrey D., Gower, Claire N., McNew, Lance B.

“…Recognition that beavers are integral components of stream ecosystems has resulted in an increase in beaver‐mediated habitat restoration projects. Beaver…”
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Impact of Pregnancy on the Pharmacokinetics and Metabolism of Nicotinamide in Humans by Fashe, Muluneh M., Le, Tien V., Gower, Megan N., Mulrenin, Ian R., Dorman, Karen F., Smith, Spenser, Fallon, John K., Dumond, Julie B., Boggess, Kim A., Lee, Craig R.

“…In pre‐eclampsia models, nicotinamide (NAM) has protective effects in pre‐eclampsia and is being evaluated as a therapeutic nutraceutical in clinical studies…”
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Simulating cheatgrass (Bromus tectorum) invasion decreases access to food resources for small mammals in sagebrush steppe by Bachen, Daniel A., Litt, Andrea R., Gower, Claire N.

“…Invasions by nonnative plants can alter the abundance of native animals, yet we know little about the mechanisms driving these changes. Shifts in vegetation…”
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Effects of aging on clinical outcomes in patients receiving genotype‐guided P2Y12 inhibitor selection after percutaneous coronary intervention by Wood, Brian, Lee, Craig R., Mulrenin, Ian R., Gower, Megan N., Rossi, Joseph S., Weck, Karen E., Stouffer, George A.

“…Study Objective To compare the clinical effectiveness of genotype‐guided P2Y12 inhibitor selection following PCI in older patients (≥70 years) and younger…”
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Gemcitabine Plus Carboplatin Versus Mitomycin, Ifosfamide, and Cisplatin in Patients With Stage IIIB or IV Non-Small-Cell Lung Cancer: A Phase III Randomized Study of the London Lung Cancer Group by Rudd, R M, Gower, N H, Spiro, S G, Eisen, T G, Harper, P G, Littler, J A H, Hatton, M, Johnson, P W M, Martin, W M C, Rankin, E M, James, L E, Gregory, W M, Qian, W, Lee, S M

“…This phase III randomized trial compared two chemotherapy regimens, gemcitabine plus carboplatin and mitomycin, ifosfamide, and cisplatin, in…”
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Recruitment of patients with lung cancer into a randomised clinical trial: experience at two centres by Spiro, S G, Gower, N H, Evans, M T, Facchini, F M, Rudd, R M

“…BACKGROUND The entry of patients into randomised clinical trials (RCTs) in lung cancer is low. A study was undertaken to assess the reasons why patients with…”
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