Search Results - "Govindarajan, Nambirajan"
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Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer's model of adult zebrafish brain
Published in PLoS biology (01-01-2020)“…It was recently suggested that supplying the brain with new neurons could counteract Alzheimer's disease (AD). This provocative idea requires further testing…”
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Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease
Published in EMBO molecular medicine (01-01-2013)“…Histone deacetylases (HDACs) are currently being discussed as promising therapeutic targets to treat neurodegenerative diseases. However, the role of specific…”
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A hippocampal insulin-growth factor 2 pathway regulates the extinction of fear memories
Published in The EMBO journal (05-10-2011)“…Extinction learning refers to the phenomenon that a previously learned response to an environmental stimulus, for example, the expression of an aversive…”
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Type 1 Interleukin-4 Signaling Obliterates Mouse Astroglia in vivo but Not in vitro
Published in Frontiers in cell and developmental biology (26-02-2020)“…Recent findings suggest that reduced neurogenesis could be one of the underlying reasons for the exacerbated neuropathology in humans, thus restoring the…”
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Sodium butyrate improves memory function in an Alzheimer's disease mouse model when administered at an advanced stage of disease progression
Published in Journal of Alzheimer's disease (01-01-2011)“…Dysregulation of histone acetylation has been implicated in the onset of age-associated memory impairment and the pathogenesis of neurodegenerative diseases…”
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Adult neurogenesis: taking stock in Stockholm
Published in Development (Cambridge) (01-10-2014)“…In May this year, Stockholm hosted a Keystone Symposium on Adult Neurogenesis, attracting scientists from around the world despite the lack of customary snow…”
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Loss of Prion Protein Leads to Age-Dependent Behavioral Abnormalities and Changes in Cytoskeletal Protein Expression
Published in Molecular neurobiology (01-12-2014)“…The cellular prion protein (PrPC) is a highly conserved protein whose exact physiological role remains elusive. In the present study, we investigated…”
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A hippocampal insulin-growth factor 2 pathway regulates the extinction of fear memories: IGF signalling regulates fear extinction
Published in The EMBO journal (05-10-2011)Get full text
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