Search Results - "Govind Babu K"

Ribociclib plus endocrine therapy for premenopausal women with hormone-receptor-positive, advanced breast cancer (MONALEESA-7): a randomised phase 3 trial by Tripathy, Debu, Im, Seock-Ah, Colleoni, Marco, Franke, Fabio, Bardia, Aditya, Harbeck, Nadia, Hurvitz, Sara A, Chow, Louis, Sohn, Joohyuk, Lee, Keun Seok, Campos-Gomez, Saul, Villanueva Vazquez, Rafael, Jung, Kyung Hae, Babu, K Govind, Wheatley-Price, Paul, De Laurentiis, Michelino, Im, Young-Hyuck, Kuemmel, Sherko, El-Saghir, Nagi, Liu, Mei-Ching, Carlson, Gary, Hughes, Gareth, Diaz-Padilla, Ivan, Germa, Caroline, Hirawat, Samit, Lu, Yen-Shen

“…In MONALEESA-2, ribociclib plus letrozole showed improved progression-free survival compared with letrozole alone as first-line treatment for postmenopausal…”
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Circulating Tumor Cell cluster phenotype allows monitoring response to treatment and predicts survival by Balakrishnan, Ajay, Koppaka, Deepak, Anand, Abhishek, Deb, Barnali, Grenci, Gianluca, Viasnoff, Virgile, Thompson, Erik W., Gowda, Harsha, Bhat, Ramray, Rangarajan, Annapoorni, Thiery, Jean Paul, Govind Babu, K., Kumar, Prashant

“…Circulating tumor cells (CTCs) are putative markers of tumor prognosis and may serve to evaluate patient’s response to chemotherapy. CTCs are often detected as…”
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A five‐year follow‐up of untreated patients with chronic lymphocytic leukaemia treated with ofatumumab and chlorambucil: final analysis of the Complement 1 phase 3 trial by Offner, Fritz, Robak, Tadeusz, Janssens, Ann, Govind Babu, K., Kloczko, Janusz, Grosicki, Sebastian, Mayer, Jiri, Panagiotidis, Panagiotis, Schuh, Anna, Pettitt, Andrew, Montillo, Marco, Werner, Olena, Vincent, Ghislaine, Khanna, Sadhvi, Hillmen, Peter

“…The Complement 1 trial investigated the efficacy and safety of ofatumumab + chlorambucil with chlorambucil monotherapy in patients with previously untreated…”
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Choosing Wisely India: ten low-value or harmful practices that should be avoided in cancer care by Pramesh, C S, Chaturvedi, Harit, Reddy, Vijay Anand, Saikia, Tapan, Ghoshal, Sushmita, Pandit, Mrinalini, Babu, K Govind, Ganpathy, K V, Savant, Dhairyasheel, Mitera, Gunita, Sullivan, Richard, Booth, Christopher M

“…The Choosing Wisely India campaign was an initiative that was established to identify low-value or potentially harmful practices that are relevant to the…”
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Chlorambucil plus ofatumumab versus chlorambucil alone in previously untreated patients with chronic lymphocytic leukaemia (COMPLEMENT 1): a randomised, multicentre, open-label phase 3 trial by Hillmen, Peter, Prof, Robak, Tadeusz, MD, Janssens, Ann, MD, Babu, K Govind, MD, Kloczko, Janusz, MD, Grosicki, Sebastian, MD, Doubek, Michael, MD, Panagiotidis, Panagiotis, MD, Kimby, Eva, MD, Schuh, Anna, MD, Pettitt, Andrew R, MRCPath, Boyd, Thomas, MD, Montillo, Marco, MD, Gupta, Ira V, MD, Wright, Oliver, BSc, Dixon, Iestyn, BSc, Carey, Jodi L, RN BSN, Chang, Chai-Ni, MS, Lisby, Steen, MD, McKeown, Astrid, PhD, Offner, Fritz, MD

“…Summary Background Treatment for patients with chronic lymphocytic leukaemia who are elderly or who have comorbidities is challenging because fludarabine-based…”
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Drug susceptibility testing of circulating lung cancer cells for personalized treatment by Balakrishnan, Ajay, Thottian, Antony George Francis, Govind Babu, K., Kumar, Prashant

“…The presence of Circulating tumor cells (CTCs) has been proven to be correlated with disease progression and the patient’s response to treatment. However, the…”
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Cancer-associated thrombotic microangiopathy by Govind Babu, K, Bhat, Gita R

“…Cancer-associated thrombotic microangiopathy refers to a group of disorders characterised by microvascular thrombosis, thrombocytopenia, and ischaemic…”
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Pro-oncogenic, intra host viral quasispecies in Diffuse large B cell lymphoma patients with occult Hepatitis B Virus infection by Sinha, Mahua, Sundar, Keerthana, Premalata, C. S., Asati, Vikas, Murali, Alka, Bajpai, Akhilesh Kumar, Davuluri, Sravanthi, Acharya, Kshitish K., Lakshmaiah, K. C., Babu K., Govind, Jacob, Linu A., Nandan, Dharam, Velayutham, Dinesh, Datta, Sibnarayan, Jayshree, R. S.

“…Non Hodgkin lymphoma, predominantly Diffuse Large B-cell Lymphoma (DLBCL) has been reported to have a significant association with Hepatitis B virus (HBV). We…”
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A Novel Ex Vivo System Using 3D Polymer Scaffold to Culture Circulating Tumor Cells from Breast Cancer Patients Exhibits Dynamic E-M Phenotypes by De, Tamasa, Goyal, Shina, Balachander, Gowri, Chatterjee, Kaushik, Kumar, Prashant, Babu K, Govind, Rangarajan, Annapoorni

“…The majority of the cancer-associated deaths is due to metastasis-the spread of tumors to other organs. Circulating tumor cells (CTCs), which are shed from the…”
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Ofatumumab plus fludarabine and cyclophosphamide in relapsed chronic lymphocytic leukemia: results from the COMPLEMENT 2 trial by Robak, Tadeusz, Warzocha, Krzysztof, Govind Babu, K., Kulyaba, Yaroslav, Kuliczkowski, Kazimierz, Abdulkadyrov, Kudrat, Loscertales, Javier, Kryachok, Iryna, Kłoczko, Janusz, Rekhtman, Grygoriy, Homenda, Wojciech, Błoński, Jerzy Z., McKeown, Astrid, Gorczyca, Michele M., Carey, Jodi L., Chang, Chai-Ni, Lisby, Steen, Gupta, Ira V., Grosicki, Sebastian

“…In this multicenter, open-label, phase III study, patients with relapsed chronic lymphocytic leukemia (CLL) were randomized (1:1) to receive ofatumumab plus…”
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Clinical Trials Facing “Serious Adverse Events” during the Ongoing COVID-19 Pandemic by Parikh, Purvish M, Mehta, Prashant, MVT, Krishna Kumar, Babu, K Govind

“…Abstract Aims and Objectives: The ongoing COVID-19 pandemic is having a profound impact on the current clinical trials. We wanted to document the extent of the…”
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Health-related quality of life in premenopausal women with hormone-receptor-positive, HER2-negative advanced breast cancer treated with ribociclib plus endocrine therapy: results from a phase III randomized clinical trial (MONALEESA-7) by Harbeck, Nadia, Franke, Fabio, Villanueva-Vazquez, Rafael, Lu, Yen-Shen, Tripathy, Debu, Chow, Louis, Babu, Govind K, Im, Young-Hyuck, Chandiwana, David, Gaur, Anil, Lanoue, Brad, Rodriguez-Lorenc, Karen, Bardia, Aditya

“…Background: This analysis evaluated patient-reported outcomes (PROs) to assess health-related quality of life (HRQoL) in the phase III MONALEESA-7 trial, which…”
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Paclitaxel injection concentrate for nanodispersion versus nab-paclitaxel in women with metastatic breast cancer: a multicenter, randomized, comparative phase II/III study by Jain, Minish M., Gupte, Smita U., Patil, Shekhar G., Pathak, Anand B., Deshmukh, Chetan D., Bhatt, Niraj, Haritha, Chiramana, Govind Babu, K., Bondarde, Shailesh A., Digumarti, Raghunadharao, Bajpai, Jyoti, Kumar, Ravi, Bakshi, Ashish V., Bhattacharya, Gouri Sankar, Patil, Poonam, Subramanian, Sundaram, Vaid, Ashok K., Desai, Chirag J., Khopade, Ajay, Chimote, Geetanjali, Bapsy, Poonamalle P., Bhowmik, Shravanti

“…Paclitaxel is widely used in the treatment of patients with metastatic breast cancer (MBC). Formulations of paclitaxel contain surfactants and solvents or…”
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Correlation between work productivity loss and EORTC QLQ-C30 and -BR23 domains from the MONALEESA-7 trial of premenopausal women with HR+/HER2− advanced breast cancer by Tripathy, Debu, Curteis, Tristan, Hurvitz, Sara, Yardley, Denise, Franke, Fabio, Babu, K. Govind, Wheatley-Price, Paul, Im, Young-Hyuck, Pencheva, Radost, Eddowes, Lucy A., Dionne, Pierre-Alexandre, Chandiwana, David, Pathak, Purnima, Lanoue, Brad, Harbeck, Nadia

“…Background: The phase III MONALEESA-7 trial (NCT02278120) assessed ribociclib + endocrine therapy (ET) versus ET in premenopausal women with HR+/HER2− advanced…”
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“Serious Adverse Events” Faced by Clinical Trials: Impact of the COVID-19 Pandemic by Parikh, Purvish M, Mehta, Prashant, MVT, Krishna Mohan, Bhattacharya, G S, Babu, K Govind

“…[...]a PubMed search using “COVID-19” done on March 28, 2020 revealed 1795 references. [5] Fighting the COVID-19 pandemic, in a way, is a step backward with…”
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Role of prephase treatment prior to definitive chemotherapy in patients with diffuse large B‐cell lymphoma by Lakshmaiah, K C, Asati, Vikas, Babu K, Govind, D, Lokanath, Jacob, Linu Abraham, M C, Suresh Babu, K N, Lokesh, L K, Rajeev, A H, Rudresh, Saldanha, Smitha, Koppaka, Deepak, Patidar, Rajesh, C S, Premalata

“…Background During the treatment of diffuse large B‐cell lymphoma (DLBCL) patients, treatment‐related toxicities are higher in the initial phase of treatment…”
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Efficacy and Safety of Ceritinib 450 mg/day with Food and 750 mg/day in Fasted State in Treatment-Naïve Patients with ALK+ Non-Small Cell Lung Cancer: Results from the ASCEND-8 Asian Subgroup Analysis by Cho, Byoung Chul, Kim, Dong-Wan, Batra, Ullas, Park, Keunchil, Kim, Sang-We, Yang, Cheng-Ta, Voon, Pei-Jye, Sriuranpong, Virote, Babu, K Govind, Amin, Khalid, Wang, Yingbo, Sen, Paramita, Slimane, Khemaies, Geater, Sarayut

“…Previous report from the ASCEND-8 trial showed consistent efficacy with less gastrointestinal (GI) toxicity in patients with anaplastic lymphoma…”
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Prognostic and predictive role of gene mutations in chronic lymphocytic leukemia: results from the pivotal phase III study COMPLEMENT1 by Tausch, Eugen, Beck, Philipp, Schlenk, Richard F, Jebaraj, Billy J, Dolnik, Anna, Yosifov, Deyan Y, Hillmen, Peter, Offner, Fritz, Janssens, Ann, Babu, K Govind, Grosicki, Sebastian, Mayer, Jiri, Panagiotidis, Panagiotis, McKeown, Astrid, Gupta, Ira V, Skorupa, Alexandra, Pallaud, Celine, Bullinger, Lars, Mertens, Daniel, Döhner, Hartmut, Stilgenbauer, Stephan

“…Next generation sequencing studies in Chronic lymphocytic leukemia (CLL) have revealed novel genetic variants that have been associated with disease…”
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Health-related quality of life and patient-reported outcomes of ofatumumab plus fludarabine and cyclophosphamide versus fludarabine and cyclophosphamide in the COMPLEMENT 2 trial of patients with relapsed CLL by Robak, Tadeusz, Warzocha, Krzysztof, Govind Babu, K., Kulyaba, Yaroslav, Kuliczkowski, Kazimierz, Abdulkadyrov, Kudrat, Loscertales, Javier, Kryachok, Iryna, Kłoczko, Janusz, Rekhtman, Grygoriy, Homenda, Wojciech, Błoński, Jerzy Z., McKeown, Astrid, Chang, Chai-Ni, Bal, Vasudha, Lisby, Steen, Gupta, Ira V., Grosicki, Sebastian

“…Chronic lymphocytic leukemia (CLL) is an incurable disease. Quality of life during treatment and periods of subsequent remission is therefore vital…”
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Pan-Asian adapted ESMO Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with metastatic colorectal cancer by Yoshino, T., Cervantes, A., Bando, H., Martinelli, E., Oki, E., Xu, R.-H., Mulansari, N.A., Govind Babu, K., Lee, M.A., Tan, C.K., Cornelio, G., Chong, D.Q., Chen, L.-T., Tanasanvimon, S., Prasongsook, N., Yeh, K.-H., Chua, C., Sacdalan, M.D., Sow (Jenson), W.J., Kim, S.T., Chacko, R.T., Syaiful, R.A., Zhang, S.Z., Curigliano, G., Mishima, S., Nakamura, Y., Ebi, H., Sunakawa, Y., Takahashi, M., Baba, E., Peters, S., Ishioka, C., Pentheroudakis, G.

“…The European Society for Medical Oncology (ESMO) Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with metastatic colorectal…”
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