Search Results - "Govil, Manika"

Disruption of an AP-2α binding site in an IRF6 enhancer is associated with cleft lip by Rahimov, Fedik, Marazita, Mary L, Visel, Axel, Cooper, Margaret E, Hitchler, Michael J, Rubini, Michele, Domann, Frederick E, Govil, Manika, Christensen, Kaare, Bille, Camille, Melbye, Mads, Jugessur, Astanand, Lie, Rolv T, Wilcox, Allen J, Fitzpatrick, David R, Green, Eric D, Mossey, Peter A, Little, Julian, Steegers-Theunissen, Regine P, Pennacchio, Len A, Schutte, Brian C, Murray, Jeffrey C

“…Nonsyndromic cleft lip with or without cleft palate has been associated with SNPs in the IRF6 gene. Now Jeff Murray and colleagues report the identification of…”
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Identifying genetic risk loci for diabetic complications and showing evidence for heterogeneity of type 1 diabetes based on complications risk by Mukhopadhyay, Nandita, Noble, Janelle A, Govil, Manika, Marazita, Mary L, Greenberg, David A

“…There is a growing body of evidence suggesting that type 1 diabetes (T1D) is a genetically heterogeneous disease. However, the extent of this heterogeneity,…”
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Caries Experience Differs between Females and Males across Age Groups in Northern Appalachia by Marazita, Mary L., Crout, Richard, McNeil, Daniel W., Govil, Manika, Feingold, Eleanor, Leslie, Elizabeth J., Shaffer, John R., Weyant, Robert J.

“…Sex disparities in dental caries have been observed across many populations, with females typically exhibiting higher prevalence and more affected teeth. In…”
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Novel caries loci in children and adults implicated by genome-wide analysis of families by Govil, Manika, Mukhopadhyay, Nandita, Weeks, Daniel E, Feingold, Eleanor, Shaffer, John R, Levy, Steven M, Vieira, Alexandre R, Slayton, Rebecca L, McNeil, Daniel W, Weyant, Robert J, Crout, Richard J, Marazita, Mary L

“…Dental caries is a common chronic disease among children and adults alike, posing a substantial health burden. Caries is affected by multiple genetic and…”
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Oral Health in a Sample of Pregnant Women from Northern Appalachia (2011-2015) by Simhan, Hyagriv N., Beach, Scott R., Zovko, Jayme G., Brown, Linda J., Strotmeyer, Stephen J., Maurer, Jennifer L., Marazita, Mary L., Crout, Richard, Shaffer, John R., Weyant, Robert J., Cooper, Margaret E., Govil, Manika, Foxman, Betsy, McNeil, Daniel W., Neiswanger, Katherine, Chapman, Stella

“…Background. Chronic poor oral health has a high prevalence in Appalachia, a large region in the eastern USA. The Center for Oral Health Research in Appalachia…”
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Follow-up association studies of chromosome region 9q and nonsyndromic cleft lip/palate by Letra, Ariadne, Menezes, Renato, Govil, Manika, Fonseca, Renata F., McHenry, Toby, Granjeiro, José M., Castilla, Eduardo E., Orioli, Iêda M., Marazita, Mary L., Vieira, Alexandre R.

“…Cleft lip/palate comprises a large fraction of all human birth defects, and is notable for its significant lifelong morbidity and complex etiology. Several…”
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MLIP: using multiple processors to compute the posterior probability of linkage by Govil, Manika, Segre, Alberto M, Vieland, Veronica J

“…Localization of complex traits by genetic linkage analysis may involve exploration of a vast multidimensional parameter space. The posterior probability of…”
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Effects of genotype on TENS effectiveness in controlling knee pain in persons with mild to moderate osteoarthritis by Govil, Manika, Mukhopadhyay, Nandita, Holwerda, Teri, Sluka, Kathleen, Rakel, Barbara, Schutte, Debra L.

“…Background This study examined the extent to which genetic variability modifies Transcutaneous Electrical Nerve Stimulation (TENS) effectiveness in…”
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Vitamin D metabolic loci and vitamin D status in Black and White pregnant women by Baca, Katharyn M., Govil, Manika, Zmuda, Joseph M., Simhan, Hyagriv N., Marazita, Mary L., Bodnar, Lisa M.

“…Several candidate genes and genome wide association studies have reported significant associations between vitamin D metabolism genes and 25-hydroxyvitamin D…”
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Vitamin D metabolic loci and preeclampsia risk in multi‐ethnic pregnant women by Baca, Katharyn M., Govil, Manika, Zmuda, Joseph M., Simhan, Hyagriv N., Marazita, Mary L., Bodnar, Lisa M.

“…Allelic variants in vitamin D metabolism genes may increase the risk of preeclampsia, but few studies have systematically tested this hypothesis. Our objective…”
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Genome scan, fine-mapping, and candidate gene analysis of non-syndromic cleft lip with or without cleft palate reveals phenotype-specific differences in linkage and association results by Marazita, Mary L, Lidral, Andrew C, Murray, Jeffrey C, Field, L Leigh, Maher, Brion S, Goldstein McHenry, Toby, Cooper, Margaret E, Govil, Manika, Daack-Hirsch, Sandra, Riley, Bridget, Jugessur, Astanand, Felix, Temis, Morene, Lina, Mansilla, M Adela, Vieira, Alexandre R, Doheny, Kim, Pugh, Elizabeth, Valencia-Ramirez, Consuelo, Arcos-Burgos, Mauricio

“…Non-syndromic orofacial clefts, i.e. cleft lip (CL) and cleft palate (CP), are among the most common birth defects. The goal of this study was to identify…”
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The PDGF-C regulatory region SNP rs28999109 decreases promoter transcriptional activity and is associated with CL/P by CHOI, Sun J, MARAZITA, Mary L, NARAYANAN, Somnya, ADELA MANSILLA, Maria, GRANJEIRO, José M, VIEIRA, Alexandre R, LIDRAL, Andrew C, MURRAY, Jeffrey C, HART, Thomas C, SUZANNE HART, P, SULIMA, Pawel P, FIELD, L. Leigh, GOLDSTEIN MCHENRY, Toby, GOVIL, Manika, COOPER, Margaret E, LETRA, Ariadne, MENEZES, Renato

“…Human linkage and association studies suggest a gene(s) for nonsyndromic cleft lip with or without cleft palate (CL/P) on chromosome 4q31-q32 at or near the…”
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Aggressive periodontitis is likely influenced by a few small effect genes by De Carvalho, Flavia M., Tinoco, Eduardo M. B., Govil, Manika, Marazita, Mary L., Vieira, Alexandre R.

“…Aim: To evaluate the inheritance mode of aggressive periodontitis in a collection of families with a similar geographic origin. Materials and Methods:…”
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CRISPLD2 Variants Including a C471T Silent Mutation May Contribute to Nonsyndromic Cleft Lip with or without Cleft Palate by Letra, Ariadne, Menezes, Renato, Cooper, Margaret E., Fonseca, Renata F., Tropp, Stephen, Govil, Manika, Granjeiro, Jose M., Imoehl, Sandra R., Mansilla, M. Adela, Murray, Jeffrey C., Castilla, Eduardo E., Orioli, Iêda M., Czeizel, Andrew E., Ma, Lian, Chiquet, Brett T., Hecht, Jacqueline T., Vieira, Alexandre R., Marazita, Mary L.

“…Objective To assess the association between nonsyndromic (NS) cleft lip with or without cleft palate (CL(P)) and single-nucleotide polymorphisms (SNPs) within…”
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Disruption of an AP-2[alpha] binding site in an IRF6 enhancer is associated with cleft lip by Rahimov, Fedik, Marazita, Mary L, Visel, Axel, Cooper, Margaret E, Hitchler, Michael J, Rubini, Michele, Domann, Frederick E, Govil, Manika, Christensen, Kaare, Bille, Camille, Melbye, Mads, Jugessur, Astanand, Lie, Rolv T, Wilcox, Allen J, Fitzpatrick, David R, Green, Eric D, Mossey, Peter A, Little, Julian, Steegers-Theunissen, Regine P, Pennacchio, Len A, Schutte, Brian C, Murray, Jeffrey C

“…Previously we have shown that nonsyndromic cleft lip with or without cleft palate (NSCL/P) is strongly associated with SNPs in IRF6 (interferon regulatory…”
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Disruption of an AP-2α binding site in an IRF6 enhancer is strongly associated with cleft lip by Rahimov, Fedik, Marazita, Mary L., Visel, Axel, Cooper, Margaret E., Hitchler, Michael J., Rubini, Michele, Domann, Frederick E., Govil, Manika, Christensen, Kaare, Bille, Camille, Melbye, Mads, Jugessur, Astanand, Lie, Rolv T., Wilcox, Allen J., Fitzpatrick, David R., Green, Eric D., Mossey, Peter A., Little, Julian, Steegers-Theunissen, Regine P., Pennacchio, Len A., Schutte, Brian C., Murray, Jeffrey C.

“…Previously we have shown that nonsyndromic cleft lip with or without cleft palate (NSCL/P) 1 , is strongly associated with SNPs in Interferon Regulatory Factor…”
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Disruption of an AP-2a binding site in an IRF6 enhancer is associated with cleft lip by RAHIMOV, Fedik, MARAZITA, Mary L, MELBYE, Mads, JUGESSUR, Astanand, LIE, Rolv T, WILCOX, Allen J, FITZPATRICK, David R, GREEN, Eric D, MOSSEY, Peter A, LITTLE, Julian, STEEGERS-THEUNISSEN, Regine P, PENNACCHIO, Len A, VISEL, Axel, SCHUTTE, Brian C, MURRAY, Jeffrey C, COOPER, Margaret E, HITCHLER, Michael J, RUBINI, Michele, DOMANN, Frederick E, GOVIL, Manika, CHRISTENSEN, Kaare, BILLE, Camille

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Extensions of the posterior probability of linkage: Distributed computation, incorportation of genetic map information, application to cleft lip and/or palate by Govil, Manika

“…The field of Statistical Genetics draws on statistics and computer science to address genetic questions. One aim of genetics is to locate on the genome the…”
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Extensions of the posterior probability of linkage: Distributed computation, incorportation of genetic map information, application to cleft lip and/or palate by Govil, Manika

“…The field of Statistical Genetics draws on statistics and computer science to address genetic questions. One aim of genetics is to locate on the genome the…”
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Model selection and Bayesian methods in statistical genetics: Summary of Group 11 contributions to Genetic Analysis Workshop 15 by Swartz, Michael D., Thomas, Duncan C., Warwick Daw, E.

“…The research presented in group 11 of the Genetic Analysis Workshop 15 (GAW15) falls into two major themes: Model selection approaches for gene mapping (both…”
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