Search Results - "Goverdhan, Gilla"

Application of [3 + 2]-Cycloaddition in the Synthesis of Valdecoxib by Reddy, Anumula Raghupathi, Goverdhan, Gilla, Sampath, Aalla, Mukkanti, Khagga, Reddy, Padi Pratap, Bandichhor, Rakeshwar

“…A large scale synthesis of valdecoxib 1 is described. Our work features potential application of [3 + 2]-dipolar cycloaddition involving enamine and in…”
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An Improved and Scalable Process for Celecoxib: A Selective Cyclooxygenase-2 Inhibitor by Reddy, Anumula Raghupathi, Sampath, Alla, Goverdhan, Gilla, Yakambaram, Bojja, Mukkanti, Kagga, Reddy, Padi Pratap

“…An improved, scalable and commercially viable process is developed for an active pharmaceutical ingredient, celecoxib…”
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Synthesis and characterization of critical process related impurities of an asthma drug – Zafirlukast by Goverdhan, Gilla, Raghupathi Reddy, Anumula, Himabindu, Vurimidi, Mahesh Reddy, Ghanta

“…Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the treatment of pulmonary disorders such as asthma. During the process development of…”
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Novel solid form of prothioconazole and its crystallographic analysis by Mittapalli, Sudhir, Doke, Suresh, Sawant, Pramod, Nagaprasada Rao, L., Ghosh, Santosh, Gilla, Goverdhan, Nambiar, Sudhir

“…Prothioconazole is a broad spectrum anti-fungal agent of triazolinthione family; it has been widely used in crop protection especially in cereals. To date,…”
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An Efficient and Telescopic Process for Valsartan, an Angiotensin II Receptor Blocker by Aalla, Sampath, Gilla, Goverdhan, Bojja, Yakambram, Anumula, Raghupathi Reddy, Vummenthala, Prabhakar Reddy, Padi, Pratap Reddy

“…An efficient, telescopic, and scalable process for an antihypertensive drug substance, valsartan with an overall yield of 58%, and ∼99.9% purity is described…”
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Concise and Alternative Synthesis of Zafirlukast, an Anti-Asthma Drug by Goverdhan, Gilla, Reddy, Anumula Raghupathi, Himabindu, Vurimidi, Reddy, Ghanta Mahesh

“…Concise and alternative synthesis of zafirlukast (1) is described. The synthesis features fewer steps, convergent synthesis, and novel intermediates…”
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Process Improvements of Prasugrel Hydrochloride: An Adenosine Diphosphate Receptor Antagonist by Aalla, Sampath, Gilla, Goverdhan, Metil, Dattatray Shamrao, Anumula, Raghupathi Reddy, Vummenthala, Prabhaker Reddy, Padi, Pratap Reddy

“…An improved process for the synthesis of prasugrel hydrochloride with an overall yield of 58%, 99.9% purity, and meeting all other quality requirements is…”
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An Improved Process for Pioglitazone and Its Pharmaceutically Acceptable Salt by Madivada, Lokeswara Rao, Anumala, Raghupathi Reddy, Gilla, Goverdhan, Alla, Sampath, Charagondla, Kavitha, Kagga, Mukkanti, Bhattacharya, Apurba, Bandichhor, Rakeshwar

“…An improved process for pioglitazone (1) is described. The process features high-yielding transformations employing inexpensive reagents and recoverable…”
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Improved Process for Ranolazine: An Antianginal Agent by Aalla, Sampath, Gilla, Goverdhan, Anumula, Raghupathi Reddy, Kurella, Srinivas, Padi, Pratap Reddy, Vummenthala, Prabhakar Reddy

“…An improved process has been developed for the active pharmaceutical ingredient, ranolazine with 99.9% purity and 47% overall yield (including three chemical…”
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An Efficient Synthesis of 1‑(2-Methoxyphenoxy)-2,3-epoxypropane: Key Intermediate of β‑Adrenoblockers by Madivada, Lokeswara Rao, Anumala, Raghupathi Reddy, Gilla, Goverdhan, Kagga, Mukkanti, Bandichhor, Rakeshwar

“…An efficient process for the preparation of 1-(2-methoxyphenoxy)-2,3-epoxypropane, a key intermediate for the synthesis of ranolazine is described…”
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New and Efficient Synthetic Approaches for the Regioisomeric and Iminium Impurities of Clopidogrel Bisulfate by Aalla, Sampath, Gilla, Goverdhan, Anumula, Raghupathi Reddy, Charagondla, Kavitha, Vummenthala, Prabhakar Reddy, Padi, Pratap Reddy

“…New and concise synthetic routes have been devised for the regioisomeric and iminium impurities of clopidogrel bisulfate. The synthesis features utilization of…”
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An Improved and Scalable Process for Zafirlukast: An Asthma Drug by Goverdhan, Gilla, Reddy, Anumula Raghupathi, Sampath, Aalla, Srinivas, Kurella, Himabindu, Vurimidi, Reddy, Ghanta Mahesh

“…An improved and scalable process for the large-scale production of zafirlukast (Accolate), an important drug for asthma, is discussed along with impurity and…”
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Identification, characterization and synthesis of impurities of zafirlukast by Goverdhan, Gilla, Reddy, Anumula Raghupathi, Srinivas, Kurella, Himabindu, Vurimidi, Reddy, Ghanta Mahesh

“…Zafirlukast is a drug in the treatment of pulmonary disorders such as asthma. During the process development of zafirlukast, five unknown impurities were…”
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Alternative Synthesis of Tadalafil: PDE5 Inhibitor by Anumula, Raghupathi Reddy, Madivada, Lokeswara Rao, Gilla, Goverdhan, Raju, V. V. N. K. Prasad, Kagga, Mukkanti, Reddy, Padi Pratap, Bhattacharya, Apurba, Bandichhor, Rakeshwar

“…Two-step alternative synthesis of tadalafil (1) is described. The synthesis features Pictet-Spengeler type reaction and DCC…”
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