Search Results - "Gouwens, Nathan"

A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation by Yao, Zizhen, van Velthoven, Cindy T.J., Nguyen, Thuc Nghi, Goldy, Jeff, Sedeno-Cortes, Adriana E., Baftizadeh, Fahimeh, Bertagnolli, Darren, Casper, Tamara, Chiang, Megan, Crichton, Kirsten, Ding, Song-Lin, Fong, Olivia, Garren, Emma, Glandon, Alexandra, Gouwens, Nathan W., Gray, James, Graybuck, Lucas T., Hawrylycz, Michael J., Hirschstein, Daniel, Kroll, Matthew, Lathia, Kanan, Lee, Changkyu, Levi, Boaz, McMillen, Delissa, Mok, Stephanie, Pham, Thanh, Ren, Qingzhong, Rimorin, Christine, Shapovalova, Nadiya, Sulc, Josef, Sunkin, Susan M., Tieu, Michael, Torkelson, Amy, Tung, Herman, Ward, Katelyn, Dee, Nick, Smith, Kimberly A., Tasic, Bosiljka, Zeng, Hongkui

“…The isocortex and hippocampal formation (HPF) in the mammalian brain play critical roles in perception, cognition, emotion, and learning. We profiled ∼1.3…”
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Systematic Integration of Structural and Functional Data into Multi-scale Models of Mouse Primary Visual Cortex by Billeh, Yazan N., Cai, Binghuang, Gratiy, Sergey L., Dai, Kael, Iyer, Ramakrishnan, Gouwens, Nathan W., Abbasi-Asl, Reza, Jia, Xiaoxuan, Siegle, Joshua H., Olsen, Shawn R., Koch, Christof, Mihalas, Stefan, Arkhipov, Anton

“…Structural rules underlying functional properties of cortical circuits are poorly understood. To explore these rules systematically, we integrated information…”
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BioNet: A Python interface to NEURON for modeling large-scale networks by Gratiy, Sergey L, Billeh, Yazan N, Dai, Kael, Mitelut, Catalin, Feng, David, Gouwens, Nathan W, Cain, Nicholas, Koch, Christof, Anastassiou, Costas A, Arkhipov, Anton

“…There is a significant interest in the neuroscience community in the development of large-scale network models that would integrate diverse sets of…”
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Systematic generation of biophysically detailed models for diverse cortical neuron types by Gouwens, Nathan W., Berg, Jim, Feng, David, Sorensen, Staci A., Zeng, Hongkui, Hawrylycz, Michael J., Koch, Christof, Arkhipov, Anton

“…The cellular components of mammalian neocortical circuits are diverse, and capturing this diversity in computational models is challenging. Here we report an…”
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Generalized leaky integrate-and-fire models classify multiple neuron types by Teeter, Corinne, Iyer, Ramakrishnan, Menon, Vilas, Gouwens, Nathan, Feng, David, Berg, Jim, Szafer, Aaron, Cain, Nicholas, Zeng, Hongkui, Hawrylycz, Michael, Koch, Christof, Mihalas, Stefan

“…There is a high diversity of neuronal types in the mammalian neocortex. To facilitate construction of system models with multiple cell types, we generate a…”
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Visual physiology of the layer 4 cortical circuit in silico by Arkhipov, Anton, Gouwens, Nathan W, Billeh, Yazan N, Gratiy, Sergey, Iyer, Ramakrishnan, Wei, Ziqiang, Xu, Zihao, Abbasi-Asl, Reza, Berg, Jim, Buice, Michael, Cain, Nicholas, da Costa, Nuno, de Vries, Saskia, Denman, Daniel, Durand, Severine, Feng, David, Jarsky, Tim, Lecoq, Jérôme, Lee, Brian, Li, Lu, Mihalas, Stefan, Ocker, Gabriel K, Olsen, Shawn R, Reid, R Clay, Soler-Llavina, Gilberto, Sorensen, Staci A, Wang, Quanxin, Waters, Jack, Scanziani, Massimo, Koch, Christof

“…Despite advances in experimental techniques and accumulation of large datasets concerning the composition and properties of the cortex, quantitative modeling…”
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Sensory processing in the Drosophila antennal lobe increases reliability and separability of ensemble odor representations by Wilson, Rachel I, Bhandawat, Vikas, Olsen, Shawn R, Gouwens, Nathan W, Schlief, Michelle L

“…Here we describe several fundamental principles of olfactory processing in the Drosophila melanogaster antennal lobe (the analog of the vertebrate olfactory…”
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Common cell type nomenclature for the mammalian brain by Miller, Jeremy A, Gouwens, Nathan W, Tasic, Bosiljka, Collman, Forrest, van Velthoven, Cindy Tj, Bakken, Trygve E, Hawrylycz, Michael J, Zeng, Hongkui, Lein, Ed S, Bernard, Amy

“…The advancement of single-cell RNA-sequencing technologies has led to an explosion of cell type definitions across multiple organs and organisms. While…”
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Signal Propagation in Drosophila Central Neurons by Gouwens, Nathan W, Wilson, Rachel I

“…Drosophila is an important model organism for investigating neural development, neural morphology, neurophysiology, and neural correlates of behaviors…”
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Inferring cortical function in the mouse visual system through large-scale systems neuroscience by Hawrylycz, Michael, Anastassiou, Costas, Arkhipov, Anton, Berg, Jim, Buice, Michael, Cain, Nicholas, Gouwens, Nathan W., Gratiy, Sergey, Iyer, Ramakrishnan, Lee, Jung Hoon, Mihalas, Stefan, Mitelut, Catalin, Olsen, Shawn, Reid, R. Clay, Teeter, Corinne, de Vries, Saskia, Waters, Jack, Zeng, Hongkui, Koch, Christof

“…The scientific mission of the Project MindScope is to understand neocortex, the part of the mammalian brain that gives rise to perception, memory,…”
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Identification of genetic markers for cortical areas using a Random Forest classification routine and the Allen Mouse Brain Atlas by Weed, Natalie, Bakken, Trygve, Graddis, Nile, Gouwens, Nathan, Millman, Daniel, Hawrylycz, Michael, Waters, Jack

“…The mammalian neocortex is subdivided into a series of cortical areas that are functionally and anatomically distinct and are often distinguished in brain…”
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Scaled, high fidelity electrophysiological, morphological, and transcriptomic cell characterization by Lee, Brian R, Budzillo, Agata, Hadley, Kristen, Miller, Jeremy A, Jarsky, Tim, Baker, Katherine, Hill, DiJon, Kim, Lisa, Mann, Rusty, Ng, Lindsay, Oldre, Aaron, Rajanbabu, Ram, Trinh, Jessica, Vargas, Sara, Braun, Thomas, Dalley, Rachel A, Gouwens, Nathan W, Kalmbach, Brian E, Kim, Tae Kyung, Smith, Kimberly A, Soler-Llavina, Gilberto, Sorensen, Staci, Tasic, Bosiljka, Ting, Jonathan T, Lein, Ed, Zeng, Hongkui, Murphy, Gabe J, Berg, Jim

“…The Patch-seq approach is a powerful variation of the patch-clamp technique that allows for the combined electrophysiological, morphological, and…”
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Use of Radiation Therapy Within the Last Year of Life Among Cancer Patients by Tseng, Yolanda D., Gouwens, Nathan W., Lo, Simon S., Halasz, Lia M., Spady, Phil, Mezheritsky, Irina, Loggers, Elizabeth

“…We examined radiation therapy (RT) use within the last year of life (LYOL). As palliative RT (PRT) has been well studied in patients with ≥6-week life…”
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The Contribution of Resurgent Sodium Current to High-Frequency Firing in Purkinje Neurons: An Experimental and Modeling Study by Khaliq, Zayd M, Gouwens, Nathan W, Raman, Indira M

“…Purkinje neurons generate high-frequency action potentials and express voltage-gated, tetrodotoxin-sensitive sodium channels with distinctive kinetics. Their…”
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Synchronization of firing in cortical fast-spiking interneurons at gamma frequencies: a phase-resetting analysis by Gouwens, Nathan W, Zeberg, Hugo, Tsumoto, Kunichika, Tateno, Takashi, Aihara, Kazuyuki, Robinson, Hugh P C

“…Fast-spiking (FS) cells in the neocortex are interconnected both by inhibitory chemical synapses and by electrical synapses, or gap-junctions. Synchronized…”
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Human neocortical expansion involves glutamatergic neuron diversification by Berg, Jim, Ting, Jonathan T., Miller, Jeremy A., Chartrand, Thomas, Buchin, Anatoly, Bakken, Trygve E., Budzillo, Agata, Dee, Nick, Gouwens, Nathan W., Hodge, Rebecca D., Kalmbach, Brian, Alfiler, Lauren, Baker, Katherine, Barkan, Eliza, Beller, Allison, Berry, Kyla, Bomben, Jasmine, Braun, Thomas, Brouner, Krissy, Crichton, Kirsten, Dalley, Rachel, de Frates, Rebecca, Desta, Tsega, Lee, Samuel Dingman, D’Orazi, Florence, Dotson, Nadezhda, Egdorf, Tom, Enstrom, Rachel, Farrell, Colin, Feng, David, Fong, Olivia, Furdan, Szabina, Gamlin, Clare, Goldy, Jeff, Gorham, Melissa, Gu, Hong, Heistek, Tim S., Heyer, Djai B., Hupp, Madie, Jarsky, Tim, Kebede, Sara, Kim, Lisa, Latimer, Caitlin, Levi, Boaz P., Link, Katherine E., Mallory, Matthew, Mann, Rusty, Marshall, Desiree, McGraw, Medea, McMillen, Delissa, Melief, Erica, Mertens, Eline J., Mezei, Leona, Mihut, Norbert, Mok, Stephanie, Molnar, Gabor, Nicovich, Philip R., Olah, Gaspar, Oldre, Aaron, Ozsvar, Attila, Park, Daniel, Peng, Hanchuan, Pom, Christina A., Potekhina, Lydia, Ransford, Shea, Rimorin, Christine, Szafer, Aaron, Thomsen, Elliot R., Tieu, Michael, Torkelson, Amy, Tung, Herman, Wakeman, Wayne, Waleboer, Femke, Ward, Katelyn, Williams, Grace, Yao, Zizhen, Yoon, Jae-Geun, Arkhipov, Anton, Barzo, Pal, Bernard, Amy, de Witt Hamer, Philip C., Ellenbogen, Richard G., Esposito, Luke, Gwinn, Ryder P., Hawrylycz, Michael J., Idema, Sander, Jones, Allan R., Keene, C. Dirk, Ko, Andrew L., Murphy, Gabe J., Ojemann, Jeffrey G., Silbergeld, Daniel L., Smith, Kimberly, Yuste, Rafael, Segev, Idan, de Kock, Christiaan P. J., Mansvelder, Huibert D., Tamas, Gabor, Koch, Christof, Lein, Ed S.

“…The neocortex is disproportionately expanded in human compared with mouse 1 , 2 , both in its total volume relative to subcortical structures and in the…”
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Signature morphoelectric properties of diverse GABAergic interneurons in the human neocortex by Lee, Brian R, Dalley, Rachel, Miller, Jeremy A, Chartrand, Thomas, Close, Jennie, Mann, Rusty, Mukora, Alice, Ng, Lindsay, Alfiler, Lauren, Baker, Katherine, Bertagnolli, Darren, Brouner, Krissy, Casper, Tamara, Csajbok, Eva, Donadio, Nicholas, Driessens, Stan L W, Egdorf, Tom, Enstrom, Rachel, Galakhova, Anna A, Gary, Amanda, Gelfand, Emily, Goldy, Jeff, Hadley, Kristen, Heistek, Tim S, Hill, Dijon, Hou, Wen-Hsien, Johansen, Nelson, Jorstad, Nik, Kim, Lisa, Kocsis, Agnes Katalin, Kruse, Lauren, Kunst, Michael, León, Gabriela, Long, Brian, Mallory, Matthew, Maxwell, Michelle, McGraw, Medea, McMillen, Delissa, Melief, Erica J, Molnar, Gabor, Mortrud, Marty T, Newman, Dakota, Nyhus, Julie, Opitz-Araya, Ximena, Ozsvár, Attila, Pham, Trangthanh, Pom, Alice, Potekhina, Lydia, Rajanbabu, Ram, Ruiz, Augustin, Sunkin, Susan M, Szöts, Ildikó, Taskin, Naz, Thyagarajan, Bargavi, Tieu, Michael, Trinh, Jessica, Vargas, Sara, Vumbaco, David, Waleboer, Femke, Walling-Bell, Sarah, Weed, Natalie, Williams, Grace, Wilson, Julia, Yao, Shenqin, Zhou, Thomas, Barzó, Pál, Bakken, Trygve, Cobbs, Charles, Dee, Nick, Ellenbogen, Richard G, Esposito, Luke, Ferreira, Manuel, Gouwens, Nathan W, Grannan, Benjamin, Gwinn, Ryder P, Hauptman, Jason S, Hodge, Rebecca, Jarsky, Tim, Keene, C Dirk, Ko, Andrew L, Korshoej, Anders Rosendal, Levi, Boaz P, Meier, Kaare, Ojemann, Jeffrey G, Patel, Anoop, Ruzevick, Jacob, Silbergeld, Daniel L, Smith, Kimberly, Sørensen, Jens Christian, Waters, Jack, Zeng, Hongkui, Berg, Jim, Capogna, Marco, Goriounova, Natalia A, Kalmbach, Brian, de Kock, Christiaan P J, Mansvelder, Huib D, Sorensen, Staci A, Tamas, Gabor, Lein, Ed S

“…Human cortex transcriptomic studies have revealed a hierarchical organization of γ-aminobutyric acid-producing (GABAergic) neurons from subclasses to a high…”
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Morphoelectric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex by Chartrand, Thomas, Dalley, Rachel, Close, Jennie, Goriounova, Natalia A, Lee, Brian R, Mann, Rusty, Miller, Jeremy A, Molnar, Gabor, Mukora, Alice, Alfiler, Lauren, Baker, Katherine, Bakken, Trygve E, Berg, Jim, Bertagnolli, Darren, Braun, Thomas, Brouner, Krissy, Casper, Tamara, Csajbok, Eva Adrienn, Dee, Nick, Egdorf, Tom, Enstrom, Rachel, Galakhova, Anna A, Gary, Amanda, Gelfand, Emily, Goldy, Jeff, Hadley, Kristen, Heistek, Tim S, Hill, DiJon, Jorstad, Nik, Kim, Lisa, Kocsis, Agnes Katalin, Kruse, Lauren, Kunst, Michael, Leon, Gabriela, Long, Brian, Mallory, Matthew, McGraw, Medea, McMillen, Delissa, Melief, Erica J, Mihut, Norbert, Ng, Lindsay, Nyhus, Julie, Oláh, Gáspár, Ozsvár, Attila, Omstead, Victoria, Peterfi, Zoltan, Pom, Alice, Potekhina, Lydia, Rajanbabu, Ramkumar, Rozsa, Marton, Ruiz, Augustin, Sandle, Joanna, Sunkin, Susan M, Szots, Ildiko, Tieu, Michael, Toth, Martin, Trinh, Jessica, Vargas, Sara, Vumbaco, David, Williams, Grace, Wilson, Julia, Yao, Zizhen, Barzo, Pal, Cobbs, Charles, Ellenbogen, Richard G, Esposito, Luke, Ferreira, Manuel, Gouwens, Nathan W, Grannan, Benjamin, Gwinn, Ryder P, Hauptman, Jason S, Jarsky, Tim, Keene, C Dirk, Ko, Andrew L, Koch, Christof, Ojemann, Jeffrey G, Patel, Anoop, Ruzevick, Jacob, Silbergeld, Daniel L, Smith, Kimberly, Sorensen, Staci A, Tasic, Bosiljka, Ting, Jonathan T, Waters, Jack, de Kock, Christiaan P J, Mansvelder, Huib D, Tamas, Gabor, Zeng, Hongkui, Kalmbach, Brian, Lein, Ed S

“…Neocortical layer 1 (L1) is a site of convergence between pyramidal-neuron dendrites and feedback axons where local inhibitory signaling can profoundly shape…”
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A guide to the BRAIN Initiative Cell Census Network data ecosystem by Hawrylycz, Michael, Martone, Maryann E, Ascoli, Giorgio A, Bjaalie, Jan G, Dong, Hong-Wei, Ghosh, Satrajit S, Gillis, Jesse, Hertzano, Ronna, Haynor, David R, Hof, Patrick R, Kim, Yongsoo, Lein, Ed, Liu, Yufeng, Miller, Jeremy A, Mitra, Partha P, Mukamel, Eran, Ng, Lydia, Osumi-Sutherland, David, Peng, Hanchuan, Ray, Patrick L, Sanchez, Raymond, Regev, Aviv, Ropelewski, Alex, Scheuermann, Richard H, Tan, Shawn Zheng Kai, Thompson, Carol L, Tickle, Timothy, Tilgner, Hagen, Varghese, Merina, Wester, Brock, White, Owen, Zeng, Hongkui, Aevermann, Brian, Allemang, David, Ament, Seth, Athey, Thomas L, Baker, Cody, Baker, Katherine S, Baker, Pamela M, Bandrowski, Anita, Banerjee, Samik, Bishwakarma, Prajal, Carr, Ambrose, Chen, Min, Choudhury, Roni, Cool, Jonah, Creasy, Heather, D'Orazi, Florence, Degatano, Kylee, Dichter, Benjamin, Ding, Song-Lin, Dolbeare, Tim, Ecker, Joseph R, Fang, Rongxin, Fillion-Robin, Jean-Christophe, Fliss, Timothy P, Gee, James, Gillespie, Tom, Gouwens, Nathan, Zhang, Guo-Qiang, Halchenko, Yaroslav O, Harris, Nomi L, Herb, Brian R, Hintiryan, Houri, Hood, Gregory, Horvath, Sam, Huo, Bingxing, Jarecka, Dorota, Jiang, Shengdian, Khajouei, Farzaneh, Kiernan, Elizabeth A, Kir, Huseyin, Kruse, Lauren, Lee, Changkyu, Lelieveldt, Boudewijn, Li, Yang, Liu, Hanqing, Liu, Lijuan, Markuhar, Anup, Mathews, James, Mathews, Kaylee L, Mezias, Chris, Miller, Michael I, Mollenkopf, Tyler, Mufti, Shoaib, Mungall, Christopher J, Orvis, Joshua, Puchades, Maja A, Qu, Lei, Receveur, Joseph P, Ren, Bing, Sjoquist, Nathan, Staats, Brian, Tward, Daniel, van Velthoven, Cindy T J, Wang, Quanxin, Xie, Fangming, Xu, Hua, Yao, Zizhen, Yun, Zhixi

“…Characterizing cellular diversity at different levels of biological organization and across data modalities is a prerequisite to understanding the function of…”
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A large-scale standardized survey of neural receptive fields in an entire column in mouse V1 by Abbasi Asl, Reza, Muslim, Arbaaz, Larkin, Josh, Takasaki, Kevin, Millman, Daniel, Denman, Daniel, Lecoq, Jerome, Arkhipov, Anton, Gouwens, Nathan W., Waters, Jack, Reid, R. Clay, de Vries, Saskia E. J.

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