Search Results - "Gouveia Roque, Cláudio"

RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo by Wong, Hovy Ho-Wai, Lin, Julie Qiaojin, Ströhl, Florian, Roque, Cláudio Gouveia, Cioni, Jean-Michel, Cagnetta, Roberta, Turner-Bridger, Benita, Laine, Romain F., Harris, William A., Kaminski, Clemens F., Holt, Christine E.

“…Nascent proteins can be positioned rapidly at precise subcellular locations by local protein synthesis (LPS) to facilitate localized growth responses. Axon…”
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Wimpy Nerves: piRNA Pathway Curbs Axon Regrowth after Injury by Roque, Cláudio Gouveia, Hengst, Ulrich

“…While PIWI-interacting RNAs (piRNAs) are primarily recognized as guardians of genome integrity, new functions of these small non-coding RNAs are emerging. In…”
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Tumor protein Tctp regulates axon development in the embryonic visual system by Roque, Cláudio Gouveia, Wong, Hovy Ho-Wai, Lin, Julie Qiaojin, Holt, Christine E

“…The transcript encoding translationally controlled tumor protein (Tctp), a molecule associated with aggressive breast cancers, was identified among the most…”
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Growth Cone Tctp Is Dynamically Regulated by Guidance Cues by Gouveia Roque, Cláudio, Holt, Christine E

“…Translationally controlled tumor protein (Tctp) contributes to retinal circuitry formation by promoting axon growth and guidance, but it remains unknown to…”
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CREB3L2-ATF4 heterodimerization defines a transcriptional hub of Alzheimer's disease gene expression linked to neuropathology by Gouveia Roque, Cláudio, Chung, Kyung Min, McCurdy, Ethan P, Jagannathan, Radhika, Randolph, Lisa K, Herline-Killian, Krystal, Baleriola, Jimena, Hengst, Ulrich

“…Gene expression is changed by disease, but how these molecular responses arise and contribute to pathophysiology remains less understood. We discover that…”
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The broken Alzheimer’s disease genome by Gouveia Roque, Cláudio, Phatnani, Hemali, Hengst, Ulrich

“…The complex pathobiology of late-onset Alzheimer’s disease (AD) poses significant challenges to therapeutic and preventative interventions. Despite these…”
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A systemic cell stress signal confers neuronal resilience toward oxidative stress in a Hedgehog-dependent manner by Chung, Kyung Min, Kim, Hyunha, Roque, Cláudio Gouveia, McCurdy, Ethan P., Nguyen, Trang T.T., Siegelin, Markus D., Hwang, Jee-Yeon, Hengst, Ulrich

“…Cells possess several conserved adaptive mechanisms to respond to stress. Stress signaling is initiated to reestablish cellular homeostasis, but its effects on…”
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A transcriptional mechanism for retromer misregulation by Roque, Cláudio Gouveia, Baleriola, Jimena, Hengst, Ulrich

“…Background Transcription factors (TFs) regulate gene expression and define cellular homeostasis. This occurs via poorly resolved combinations of TFs that…”
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A transcriptional mechanism for retromer misregulation: Molecular and cell biology: Endo‐lysosomal/trafficking dysfunction by Roque, Cláudio Gouveia, Baleriola, Jimena, Hengst, Ulrich

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Evaluation of Juvenile Animal Studies for Pediatric CNS-Targeted Compounds: A Regulatory Perspective by van der Laan, Jan Willem, van Malderen, Karen, de Jager, Nico, Duarte, Dinah, Egger, Gunter F., Lavergne, Fabien, Roque, Cláudio Gouveia, Vieira, Isabel, Wiesner, Lutz, Carleer, Jacqueline

“…Central nervous system (CNS)-targeted products are an important category of pediatric pharmaceuticals. In view of the significant postnatal maturation of the…”
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Transcriptional deregulation in Parkinson’s disease by ATF4 transcription factor heterodimers (2891) by Jagannathan, Radhika, Roque, Claudio Gouveia, Hengst, Ulrich

“…Abstract only…”
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Tctp in Neuronal Circuitry Assembly by Roque, Cláudio Gouveia, Holt, Christine E

“…Although tctp expression in many areas of the human brain was reported more than 15 years ago, little was known about how it functions in neurons. The early…”
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A Role for TCTP in Neural Circuitry Formation by Roque, Cláudio André Gouveia Martins

“…With 86 billion neurons in the human brain, the ordered array of neuronal pathways is an exceptionally complex web of accurately connected axonal and dendritic…”
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