Search Results - "Gouveia Júnior, Florêncio Sousa"
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New nitrosyl ruthenium complexes with combined activities for multiple cardiovascular disorders
Published in Dalton transactions : an international journal of inorganic chemistry (25-04-2023)“…Nitrosyl ruthenium complexes are promising platforms for nitric oxide (NO) and nitroxyl (HNO) release, which exert their therapeutic application. In this…”
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Anti-asthmatic effect of nitric oxide metallo-donor FOR811A [cis-[Ru(bpy)2(2-MIM)(NO)](PF6)3] in the respiratory mechanics of Swiss mice
Published in PloS one (2021)“…We aimed at evaluating the anti-asthmatic effect of cis-[Ru(bpy)2(2-MIM)(NO)](PF6)3 (FOR811A), a nitrosyl-ruthenium compound, in a murine model of allergic…”
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Nitro-imidazole-based ruthenium complexes with antioxidant and anti-inflammatory activities
Published in Journal of inorganic biochemistry (01-05-2020)“…Inflammation is a physiological process triggered in response to tissue damage, and involves events related to cell recruitment, cytokines release and reactive…”
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Anti-asthmatic effect of nitric oxide metallo-donor FOR811A [cis-[Ru.sub.3] in the respiratory mechanics of Swiss mice
Published in PloS one (12-03-2021)“…We aimed at evaluating the anti-asthmatic effect of cis-[Ru(bpy).sub.2 (2-MIM)(NO)](PF.sub.6).sub.3 (FOR811A), a nitrosyl-ruthenium compound, in a murine model…”
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Synthesis and potential vasorelaxant effect of a novel ruthenium-based nitro complex
Published in Journal of inorganic biochemistry (01-03-2022)“…This study aimed to investigate the synthesis and potential vasodilator effect of a novel ruthenium complex, cis-[Ru(bpy)2(2-MIM)(NO2)]PF6…”
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The nitric oxide pathway is involved in the anti-inflammatory effect of the rutheniumcomplex [Ru(bpy)2(2-MIM)(NO)](PF6)3
Published in European journal of pharmacology (15-04-2022)“…Metal coordination complexes are chemotherapeutic and anti-inflammatory agents. The ruthenium complex FOR811A ([Ru(bpy)2(2-MIM)Cl](PF6)3) FOR811A was evaluated…”
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A divergent mode of activation of a nitrosyl iron complex with unusual antiangiogenic activity
Published in Journal of inorganic biochemistry (01-09-2020)“…Nitric oxide (NO) and nitroxyl (HNO) have gained broad attention due to their roles in several physiological and pathophysiological processes. Remarkably,…”
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Anti-asthmatic effect of nitric oxide metallo-donor FOR811A [cis-[Ru
Published in PloS one (12-03-2021)“…We aimed at evaluating the anti-asthmatic effect of cis-[Ru(bpy).sub.2 (2-MIM)(NO)](PF.sub.6).sub.3 (FOR811A), a nitrosyl-ruthenium compound, in a murine model…”
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