Search Results - "Gouveia, Virginia M."
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Oxaprozin-Loaded Lipid Nanoparticles towards Overcoming NSAIDs Side-Effects
Published in Pharmaceutical research (01-02-2016)“…Purpose Nanostructured Lipid Carriers (NLCs) loading oxaprozin were developed to address an effective drug packaging and targeted delivery, improving the drug…”
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Metabolically Active, Fully Hydrolysable Polymersomes
Published in Angewandte Chemie International Edition (26-03-2019)“…The synthesis and aqueous self‐assembly of a new class of amphiphilic aliphatic polyesters are presented. These AB block polyesters comprise polycaprolactone…”
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Correction to “A Multiscale Study of Phosphorylcholine Driven Cellular Phenotypic Targeting”
Published in ACS central science (24-07-2024)“…[This corrects the article DOI: 10.1021/acscentsci.2c00146.]…”
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Non-Biologic Nanodelivery Therapies for Rheumatoid Arthritis
Published in Journal of biomedical nanotechnology (01-10-2015)“…Rheumatoid arthritis is a common chronic inflammatory disease characterized by progressive bone and cartilage destruction causing severe functional…”
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Polymersomes Eradicating Intracellular Bacteria
Published in ACS nano (28-07-2020)“…Mononuclear phagocytes such as monocytes, tissue-specific macrophages, and dendritic cells are primary actors in both innate and adaptive immunity. These…”
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Hyaluronic acid-conjugated pH-sensitive liposomes for targeted delivery of prednisolone on rheumatoid arthritis therapy
Published in Nanomedicine (London, England) (01-05-2018)“…The treatment of rheumatoid arthritis remains a challenge as available therapies still entail the risk of deleterious off-target effects. The present study…”
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Macrophage Targeting pH Responsive Polymersomes for Glucocorticoid Therapy
Published in Pharmaceutics (15-11-2019)“…Glucocorticoid (GC) drugs are the cornerstone therapy used in the treatment of inflammatory diseases. Here, we report pH responsive poly(2-methacryloyloxyethyl…”
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A Multiscale Study of Phosphorylcholine Driven Cellular Phenotypic Targeting
Published in ACS central science (27-07-2022)“…Phenotypic targeting requires the ability of the drug delivery system to discriminate over cell populations expressing a particular receptor combination. Such…”
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Metabolically Active, Fully Hydrolysable Polymersomes
Published in Angewandte Chemie (26-03-2019)“…The synthesis and aqueous self‐assembly of a new class of amphiphilic aliphatic polyesters are presented. These AB block polyesters comprise polycaprolactone…”
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Targeting Macrophages and Synoviocytes Intracellular Milieu to Augment Anti‐Inflammatory Drug Potency
Published in Advanced therapeutics (01-03-2022)“…Using a preclinical in vivo model of arthritis and the gold standard disease‐modifying anti‐rheumatic drug, methotrexate, pH‐responsive phosphorylcholine…”
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Targeting Macrophages and Synoviocytes Intracellular Milieu to Augment Anti‐Inflammatory Drug Potency (Adv. Therap. 3/2022)
Published in Advanced therapeutics (01-03-2022)“…Selective accumulation of pH‐responsive polymersomes in the synovium of arthritic joints empower the target delivery of drug molecules within macrophages and…”
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