Search Results - "Gourvenec, Françoise"

Assessment through chemical synthesis of the size of the heparin sequence involved in thrombin inhibition by Duchaussoy, Philippe, Jaurand, Guy, Driguez, Pierre-A., Lederman, Isidore, Ceccato, Marie-L., Gourvenec, Françoise, Strassel, Jean-M., Sizun, Philippe, Petitou, Maurice, Herbert, Jean-M.

“…Deca- to eicosasaccharides having the generic structure methyl(sodium 2,3-di- O-methyl-4- O-sodium sulfonato-α- l-idopyranosyluronate)-(1→4)-[(2,3,6-tri-…”
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Experimental Proof for the Structure of a Thrombin-Inhibiting Heparin Molecule by Petitou, Maurice, Imberty, Anne, Duchaussoy, Philippe, Driguez, Pierre-Alexandre, Ceccato, Marie-Line, Gourvenec, Françoise, Sizun, Philippe, Hérault, Jean-Pascal, Pérez, Serge, Herbert, Jean-Marc

“…Kinetic studies of thrombin inhibition by antithrombin in the presence of heparin have shown that thrombin binds to heparin in a preformed heparin–antithrombin…”
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Synthesis and Pharmacological Properties of a Close Analogue of an Antithrombotic Pentasaccharide (SR 90107A/ORG 31540) by Petitou, Maurice, Duchaussoy, Philippe, Jaurand, Guy, Gourvenec, Françoise, Lederman, Isidore, Strassel, Jean-Marc, Bârzu, Tereza, Crépon, Bertrand, Hérault, Jean-Pascal, Lormeau, Jean-Claude, Bernat, André, Herbert, Jean-Marc

“…The synthetic pentasaccharide (1) corresponding to the heparin sequence which binds to, and activates, antithrombin III (AT III) is a potent antithrombotic…”
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Identification of a hexasaccharide sequence able to inhibit thrombin and suitable for ‘polymerisation’ by Duchaussoy, Philippe, Jaurand, Guy, Driguez, Pierre-A., Lederman, Isidore, Gourvenec, Françoise, Strassel, Jean-M., Sizun, Philippe, Petitou, Maurice, Herbert, Jean-M.

“…Three hexasaccharides, having from low to very high affinity for antithrombin, were synthesised from disaccharide building block precursors. One of them,…”
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Corrigendum to “Identification of a hexasaccharide sequence able to inhibit thrombin and suitable for ‘polymerisation’”: [Carbohydrate Research 317 (1999) 63–84] by Duchaussoy, Philippe, Jaurand, Guy, Driguez, Pierre-A., Lederman, Isidore, Gourvenec, Françoise, Strassel, Jean-M., Sizun, Philippe, Petitou, Maurice, Herbert, Jean-M.

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