Search Results - "Goulding, Scott P"

The Role of Mass Spectrometry and Proteogenomics in the Advancement of HLA Epitope Prediction by Creech, Amanda L., Ting, Ying S., Goulding, Scott P., Sauld, John F.K., Barthelme, Dominik, Rooney, Michael S., Addona, Terri A., Abelin, Jennifer G.

“…A challenge in developing personalized cancer immunotherapies is the prediction of putative cancer‐specific antigens. Currently, predictive algorithms are used…”
Get full text

Nerve injury-induced changes in Homer/glutamate receptor signaling contribute to the development and maintenance of neuropathic pain by Obara, Ilona, Goulding, Scott P., Hu, Jia-Hua, Klugmann, Matthias, Worley, Paul F., Szumlinski, Karen K.

“…While group 1 metabotropic glutamate receptors (mGluRs) and ionotropic N-methyl-d-aspartate (NMDA) receptors regulate nociception, the precise molecular…”
Get full text

Defining HLA-II Ligand Processing and Binding Rules with Mass Spectrometry Enhances Cancer Epitope Prediction by Abelin, Jennifer G., Harjanto, Dewi, Malloy, Matthew, Suri, Prerna, Colson, Tyler, Goulding, Scott P., Creech, Amanda L., Serrano, Lia R., Nasir, Gibran, Nasrullah, Yusuf, McGann, Christopher D., Velez, Diana, Ting, Ying S., Poran, Asaf, Rothenberg, Daniel A., Chhangawala, Sagar, Rubinsteyn, Alex, Hammerbacher, Jeff, Gaynor, Richard B., Fritsch, Edward F., Greshock, Joel, Oslund, Rob C., Barthelme, Dominik, Addona, Terri A., Arieta, Christina M., Rooney, Michael S.

“…Increasing evidence indicates CD4+ T cells can recognize cancer-specific antigens and control tumor growth. However, it remains difficult to predict the…”
Get full text

Chronic MAP4343 reverses escalated alcohol drinking in a mouse model of alcohol use disorder by Macedo, Giovana C, Kreifeldt, Max, Goulding, Scott P, Okhuarobo, Agbonlahor, Sidhu, Harpreet, Contet, Candice

“…Alcohol use disorders can be driven by negative reinforcement. Alterations of the microtubule cytoskeleton have been associated with mood regulation in the…”
Get full text

Maximizing Peptide Identification Events in Proteomic Workflows Using Data-Dependent Acquisition (DDA) by Bateman, Nicholas W., Goulding, Scott P., Shulman, Nicholas J., Gadok, Avinash K., Szumlinski, Karen K., MacCoss, Michael J., Wu, Christine C.

“…Current analytical strategies for collecting proteomic data using data-dependent acquisition (DDA) are limited by the low analytical reproducibility of the…”
Get full text

Increased Alcohol-Drinking Induced by Manipulations of mGlu5 Phosphorylation within the Bed Nucleus of the Stria Terminalis by Campbell, Rianne R, Domingo, Racquel D, Williams, Amy R, Wroten, Melissa G, McGregor, Hadley A, Waltermire, Ryan S, Greentree, Daniel I, Goulding, Scott P, Thompson, Andrew B, Lee, Kaziya M, Quadir, Sema G, Jimenez Chavez, C Leonardo, Coelho, Michal A, Gould, Adam T, von Jonquieres, Georg, Klugmann, Matthias, Worley, Paul F, Kippin, Tod E, Szumlinski, Karen K

“…The bed nucleus of the stria terminalis (BNST) is part of the limbic-hypothalamic system important for behavioral responses to stress, and glutamate…”
Get full text

Systemic Administration of the Cyclin‐Dependent Kinase Inhibitor (S)‐CR8 Selectively Reduces Escalated Ethanol Intake in Dependent Rats by Goulding, Scott P., de Guglielmo, Giordano, Carrette, Lieselot L.G., George, Olivier, Contet, Candice

“…Background Chronic exposure to ethanol (EtOH) and other drugs of abuse can alter the expression and activity of cyclin‐dependent kinase 5 (CDK5) and its…”
Get full text

Defining HLA-II ligand processing and binding rules with mass spectrometry enhances cancer epitope prediction by Abelin, Jennifer G., Harjanto, Dewi, Malloy, Matthew, Suri, Prerna, Colson, Tyler, Goulding, Scott P., Creech, Amanda L., Serrano, Lia R., Nasir, Gibran, Nasrullah, Yusuf, McGann, Christopher D., Velez, Diana, Ting, Ying S., Poran, Asaf, Rothenberg, Daniel A., Chhangawala, Sagar, Rubinsteyn, Alex, Hammerbacher, Jeff, Gaynor, Richard B., Fritsch, Edward F., Greshock, Joel, Oslund, Rob C., Barthelme, Dominik, Addona, Terri A., Arieta, Christina M., Rooney, Michael S.

Get full text

A mass spectrometry-based proteomic analysis of Homer2-interacting proteins in the mouse brain by Goulding, Scott P., Szumlinski, Karen K., Contet, Candice, MacCoss, Michael J., Wu, Christine C.

“…In the brain, the Homer protein family modulates excitatory signal transduction and receptor plasticity through interactions with other proteins in dendritic…”
Get full text

Binge Drinking Upregulates Accumbens mGluR5-Homer2-PI3K Signaling: Functional Implications for Alcoholism by Cozzoli, Debra K, Goulding, Scott P, Zhang, Ping Wu, Xiao, Bo, Hu, Jia-Hua, Ary, Alexis W, Obara, Ilona, Rahn, Alison, Abou-Ziab, Hoda, Tyrrel, Burgundy, Marini, Christina, Yoneyama, Naomi, Metten, Pamela, Snelling, Christopher, Dehoff, Marlin H, Crabbe, John C, Finn, Deborah A, Klugmann, Matthias, Worley, Paul F, Szumlinski, Karen K

“…The glutamate receptor-associated protein Homer2 regulates alcohol-induced neuroplasticity within the nucleus accumbens (NAC), but the precise intracellular…”
Get full text

Differential Effects of Chronic Ethanol Consumption and Withdrawal on Homer/Glutamate Receptor Expression in Subregions of the Accumbens and Amygdala of P Rats by Obara, Ilona, Bell, Richard L., Goulding, Scott P., Reyes, Cindy M., Larson, Lindsay A., Ary, Alexis W., Truitt, William A., Szumlinski, Karen K.

“…Background:  Homer proteins are constituents of scaffolding complexes that regulate the trafficking and function of central Group1 metabotropic glutamate…”
Get full text

Systematic discovery and validation of T cell targets directed against oncogenic KRAS mutations by Choi, Jaewon, Goulding, Scott P., Conn, Brandon P., McGann, Christopher D., Dietze, Jared L., Kohler, Jessica, Lenkala, Divya, Boudot, Antoine, Rothenberg, Daniel A., Turcott, Paul J., Srouji, John R., Foley, Kendra C., Rooney, Michael S., van Buuren, Marit M., Gaynor, Richard B., Abelin, Jennifer G., Addona, Terri A., Juneja, Vikram R.

“…Oncogenic mutations in KRAS can be recognized by T cells on specific class I human leukocyte antigen (HLA-I) molecules, leading to tumor control. To date, the…”
Get full text

Label-free differential analysis of murine postsynaptic densities by Goulding, Scott P, Maccoss, Michael J, Wu, Christine C

“…This chapter provides detailed methodology for the enrichment and label-free differential analysis of postsynaptic density (PSD) proteins. Methods discussed…”
Get more information

Homers at the Interface between Reward and Pain by Obara, Ilona, Goulding, Scott P, Gould, Adam T, Lominac, Kevin D, Hu, Jia-Hua, Zhang, Ping Wu, von Jonquieres, Georg, Dehoff, Marlin, Xiao, Bo, Seeburg, Peter H, Worley, Paul F, Klugmann, Matthias, Szumlinski, Karen K

“…Pain alters opioid reinforcement, presumably via neuroadaptations within ascending pain pathways interacting with the limbic system. Nerve injury increases…”
Get full text

Abstract PO-015: Systematic discovery of KRAS neoantigens by Choi, Jaewon, Goulding, Scott P, Conn, Brandon P., McGann, Christopher D., Dietze, Jared L., Kohler, Jessica, Lenkala, Divya R., Boudot, Antoine, Rothenberg, Daniel A., Turcott, Paul J., Srouji, John S., Rooney, Michael S., van Buuren, Marit M., Gaynor, Richard B., Abelin, Jennifer G., Addona, Terri A., Juneja, Vikram R.

“…Response rates to immunotherapies in pancreatic ductal adenocarcinoma (PDAC) patients are low. However, cases with long-term survival have been correlated with…”
Get full text

Accumbens Homer2‐mediated signaling: a factor contributing to mouse strain differences in alcohol drinking? by Goulding, S. P., Obara, I., Lominac, K. D., Gould, A. T., Miller, B. W., Klugmann, M., Szumlinski, K. K.

“…Alcohol‐induced increases in nucleus accumbens glutamate actively regulate alcohol consumption, and the alcohol responsiveness of corticoaccumbens glutamate…”
Get full text