Search Results - "Gould, A L"

Strain-level diversity of symbiont communities between individuals and populations of a bioluminescent fish by Gould, A. L., Donohoo, S. A., Román, E. D., Neff, E. E.

“…The bioluminescent symbiosis involving the urchin cardinalfish, Siphamia tubifer , and Photobacterium mandapamensis , a luminous member of the Vibrionaceae, is…”
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Symbiosis initiation in the bacterially luminous sea urchin cardinalfish Siphamia versicolor by Dunlap, P. V., Gould, A. L., Wittenrich, M. L., Nakamura, M.

“…To determine how each new generation of the sea urchin cardinalfish Siphamia versicolor acquires the symbiotic luminous bacterium Photobacterium mandapamensis,…”
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Serum prostate-specific antigen as a predictor of prostate volume in men with benign prostatic hyperplasia by Roehrborn, Claus G., Boyle, Peter, Gould, A.Lawrence, Waldstreicher, Joanne

“…Objectives. To assess the utility of prostate-specific antigen (PSA) as a predictor of prostate volume by characterizing the relationship between prostate…”
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Cholesterol reduction yields clinical benefit: Impact of statin trials by GOULD, A. L, ROSSOUW, J. E, SANTANELLO, N. C, HEYSE, J. F, FURBERG, C. D

“…We determined the effect of incorporating the results of eight recently published trials of Hmg CoA reductase inhibitors ("statins") on the conclusions from…”
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Genomic analysis of a cardinalfish with larval homing potential reveals genetic admixture in the Okinawa Islands by Gould, A. L., Dunlap, P. V.

“…Discrepancies between potential and observed dispersal distances of reef fish indicate the need for a better understanding of the influence of larval behaviour…”
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Prostate volume predicts outcome of treatment of benign prostatic hyperplasia with finasteride: Meta-analysis of randomized clinical trials by Boyle, Peter, Lawrence Gould, A., Roehrborn, Claus G.

“…Abstract Six randomized clinical trials have compared at least 1 year of 5 mg finasteride to placebo in the treatment of clinical benign prostatic hyperplasia…”
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Chromosome-Level Genome Assembly of the Bioluminescent Cardinalfish Siphamia tubifer: An Emerging Model for Symbiosis Research by Gould, A. L., Henderson, J. B., Lam, A. W.

“…Abstract The bioluminescent symbiosis involving the sea urchin cardinalfish Siphamia tubifer and the luminous bacterium Photobacterium mandapamensis is an…”
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An Evaluation of Computer-Aided Disproportionality Analysis for Post-Marketing Signal Detection by Lehman, H P, Chen, J, Gould, A L, Kassekert, R, Beninger, P R, Carney, R, Goldberg, M, Goss, M A, Kidos, K, Sharrar, R G, Shields, K, Sweet, A, Wiholm, B E, Honig, P K

“…To understand the value of computer‐aided disproportionality analysis (DA) in relation to current pharmacovigilance signal detection methods, four products…”
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Life history of the symbiotically luminous cardinalfish Siphamia tubifer (Perciformes: Apogonidae) by Gould, A. L., Dougan, K. E., Koenigbauer, S. T., Dunlap, P. V.

“…Characteristics of the life history of the coral reef‐dwelling cardinalfish Siphamia tubifer, from Okinawa, Japan, were defined. A paternal mouthbrooder, S…”
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Cholesterol reduction yields clinical benefit : a new look at old data by GOULD, A. L, ROSSOUW, J. E, SANTANELLO, N. C, HEYSE, J. F, FURBERG, C. D

“…There has been a continuing debate about the overall benefit of cholesterol lowering. We performed a novel meta-analysis of all randomized trials of more than…”
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PhRMA Perspective on Population and Individual Bioequivalence by Barrett, Jeffrey S., Batra, Vijay, Chow, Andrew, Cook, Jack, Gould, A. Lawrence, Heller, Allen H., Lo, Man-Wai, Patterson, Scott D., Smith, Brian P., Stritar, Jeffrey A., Vega, Jose M., Zariffa, Névine

“…The Food and Drug Administration (FDA) issued a second‐draft guidance in August 1999 on the subject of in vivo bioequivalence, which is based on the concepts…”
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Mitigation of Surfactant Erythrocyte Toxicity by Egg Phosphatidylcholine by GOULD, LARISSA A., LANSLEY, ALISON B., BROWN, MARC B., FORBES, BEN, MARTIN, GARY P.

“…Polyoxyethylene alkyl ether surfactants have been shown to have excellent penetration enhancing abilities although they are associated with a high level of…”
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Multi-centre trial analysis revisited by Gould, A. Lawrence

“…Analyses of multi‐centre trials must consider the effects of the individual centres and the possibility of non‐constancy of treatment effect differences among…”
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Modifying the design of ongoing trials without unblinding by Gould, A. Lawrence, Shih, W. Joseph

“…Conventional group sequential designs provide an objective basis for reducing the sample size of a trial if the difference between the treatments is much more…”
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Baseline differences in A1C explain apparent differences in efficacy of sitagliptin, rosiglitazone and pioglitazone by Chapell, R, Gould, A.L, Alexander, C.M

“…Published studies of patients treated with rosiglitazone or pioglitazone have reported greater reductions in HbA1c (A1C) than studies of patients treated with…”
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Development, growth, and reproduction of the cyclopoid copepod Limnoithona tetraspina in the upper San Francisco Estuary by Gould, AL, Kimmerer, WJ

“…Limnoithona tetraspina is a small cyclopoid copepod that was introduced to the San Francisco Estuary (SFE), USA, in 1993 and became the most abundant copepod…”
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Update to the PhRMA Perspective on Population and Individual Bioequivalence by Barrett, Jeffrey S., Batra, Vijay, Chow, Andrew, Cook, Jack, Gould, A. Lawrence, Heller, Allen H., Lo, Man-Wai, Patterson, Scott D., Smith, Brian P., Stritar, Jeffrey A., Vega, Jose M., Zariffa, Névine

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Sample size re-estimation: recent developments and practical considerations by Gould, A. Lawrence

“…Interim findings of a clinical trial often will be useful for increasing the sample size if necessary to provide the required power against the null hypothesis…”
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Practical pharmacovigilance analysis strategies by Lawrence Gould, A.

“…Purpose To compare two recently proposed Bayesian methods for quantitative pharmacovigilance with respect to assumptions and results, and to describe some…”
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Group sequential extensions of a standard bioequivalence testing procedure by Gould, A L

“…Bioequivalence trials compare the relative bioavailability of different formulations of a drug. Regulatory requirements for demonstrating average…”
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