Search Results - "Goukos, Dimitris"

Carbapenemase-Producing Klebsiella pneumoniae Bloodstream Infections: Lowering Mortality by Antibiotic Combination Schemes and the Role of Carbapenems by DAIKOS, George L, TSAOUSI, Sophia, GEORGIADOU, Sarah, MARKOGIANNAKIS, Antonis, GOUKOS, Dimitris, SKOUTELIS, Athanasios, TZOUVELEKIS, Leonidas S, ANYFANTIS, Ioannis, PSICHOGIOU, Mina, ARGYROPOULOU, Athina, STEFANOU, Ioanna, SYPSA, Vana, MIRIAGOU, Vivi, NEPKA, Martha

“…Carbapenemase-producing Klebsiella pneumoniae strains (CP-Kps) are currently among the most important nosocomial pathogens. An observational study was…”
Get full text

Ex Vivo Evaluation of Glutamine Treatment in Sepsis and Trauma in a Human Peripheral Blood Mononuclear Cells Model by Briassouli, Efrossini, Tzanoudaki, Marianna, Goukos, Dimitris, Vardas, Kostas, Briassoulis, Panagiotis, Ilia, Stavroula, Kanariou, Maria, Routsi, Christina, Nanas, Serafim, Daikos, George L, Briassoulis, George

“…We aimed to assess the lipopolysaccharide (LPS), or heat shock (HS) induction, and glutamine-modulating effects on heat shock protein-90α (HSP90α) and…”
Get full text

Glutamine suppresses Hsp72 not Hsp90α and is not inducing Th1, Th2, or Th17 cytokine responses in human septic PBMCs by Briassouli, Efrossini, M.D, Goukos, Dimitris, M.S, Daikos, George, M.D., Ph.D, Apostolou, Kleovoulos, M.D, Routsi, Christina, M.D., Ph.D, Nanas, Serafim, M.D., Ph.D, Briassoulis, George, M.D., Ph.D

“…Abstract Objective l -Alanyl-glutamine (L-Ala-Gln) is a pharmaco-nutrient commonly used in nutrition regimens due to its immunomodulatory effects. In…”
Get full text

Immunoparalysis: Clinical and immunological associations in SIRS and severe sepsis patients by Papadopoulos, Panagiotis, Pistiki, Aikaterini, Theodorakopoulou, Maria, Christodoulopoulou, Theodora, Damoraki, Georgia, Goukos, Dimitris, Briassouli, Efrossini, Dimopoulou, Ioanna, Armaganidis, Apostolos, Nanas, Serafim, Briassoulis, George, Tsiodras, Sotirios

“…This study was designed to identify changes in the monocytic membrane marker HLA-DR and heat shock proteins (HSPs) in relation to T-regulatory cells (T-regs)…”
Get full text

Crohn's disease-associated mucosal factors regulate the expression of TNF-like cytokine 1A and its receptors in primary subepithelial intestinal myofibroblasts and intestinal epithelial cells by Bamias, Giorgos, Filidou, Eirini, Goukos, Dimitris, Valatas, Vasilis, Arvanitidis, Konstantinos, Panagopoulou, Maria, Kouklakis, Georgios, Daikos, George L, Ladas, Spiros D, Kolios, George

“…Intestinal subepithelial myofibroblasts (SEMFs) exert a profibrotic role in Crohn's disease (CD). Tumor necrosis factor-like cytokine 1A (TL1A) and its…”
Get full text

High serum lipopolysaccharide binding protein is associated with increased mortality in patients with decompensated cirrhosis by Agiasotelli, Danai, Alexopoulou, Alexandra, Vasilieva, Larisa, Hadziyannis, Emilia, Goukos, Dimitris, Daikos, George L., Dourakis, Spyros P.

“…Background & Aims Lipopolysaccharide‐binding‐protein (LBP) is an acute‐phase‐protein produced by hepatocytes. Changes in LBP are associated with the dynamics…”
Get full text

Increased glucocorticoid receptor expression in sepsis is related to heat shock proteins, cytokines, and cortisol and is associated with increased mortality by Vardas, Konstantinos, Ilia, Stavroula, Sertedaki, Amalia, Charmandari, Evangelia, Briassouli, Efrossini, Goukos, Dimitris, Apostolou, Kleovoulos, Psarra, Katerina, Botoula, Efthimia, Tsagarakis, Stylianos, Magira, Eleni, Routsi, Christina, Stratakis, Constantine A., Nanas, Serafim, Briassoulis, George

“…Background The purposes of this study are to examine if the human glucocorticoid receptor (hGR) isoform-α mRNA and hGR protein expressions are deficient in the…”
Get full text

Comparative study of candidate housekeeping genes for quantification of target gene messenger RNA expression by real-time PCR in patients with inflammatory bowel disease by Bamias, Giorgos, Goukos, Dimitris, Laoudi, Eyfrosyni, Balla, Iliana G, Siakavellas, Spyros I, Daikos, George L, Ladas, Spiros D

“…Mucosal expression of immunological mediators is modified in inflammatory bowel disease (IBD). Quantification of target gene messenger RNA (mRNA) transcripts…”
Get full text

Response to Lipopolysaccharide binding protein predicts decompensated cirrhosis mortality? It is too early by Agiasotelli, Danai, Alexopoulou, Alexandra, Vasilieva, Larisa, Hadziyannis, Emilia, Goukos, Dimitris, Daikos, George L., Dourakis, Spyros P.

Get full text

Glutamine suppresses Hsp72 not Hsp90[alpha] and is not inducing Th1, Th2, or Th17 cytokine responses in human septic PBMCs by Briassouli, Efrossini, Goukos, Dimitris, Daikos, George, Apostolou, Kleovoulos, Routsi, Christina, Nanas, Serafim, Briassoulis, George

“…Objective l-Alanyl-glutamine (L-Ala-Gln) is a pharmaco-nutrient commonly used in nutrition regimens due to its immunomodulatory effects. In critically ill…”
Get full text

Glutamine May Repress the Weak LPS and Enhance the Strong Heat Shock Induction of Monocyte and Lymphocyte HSP72 Proteins but May Not Modulate the HSP72 mRNA in Patients with Sepsis or Trauma by Briassoulis, George, Daikos, George, Apostolou, Kleovoulos, Vardas, K., Nanas, S., Routsi, C., Goukos, D., Tzanoudaki, Marianna, Briassouli, Efrossini, Kanariou, Maria

“…Objective. We assessed the lipopolysaccharide (LPS) or heat shock (HS) induction of heat shock protein-72 (HSP72) in peripheral blood mononuclear cells (PBMCs)…”
Get full text

Predictors of tissue healing in ulcerative colitis patients treated with anti-TNF by Viazis, Nikos, Giakoumis, Marios, Bamias, Giorgos, Goukos, Dimitris, Koukouratos, Theodoros, Katopodi, Konstantina, Karatzas, Pantelis, Triantos, Christos, Tsolias, Chrisostomos, Theocharis, Georgios, Daikos, George L, Ladas, Spyros D, Karamanolis, Dimitrios G, Mantzaris, Gerasimos J

“…Abstract Aim To identify factors predicting mucosal healing in ulcerative colitis patients treated with anti-TNFα agents with or without azathioprine. Methods…”
Get full text

Systemic levels of human β-defensin 1 are elevated in patients with cirrhosis by Kaltsa, Garyfallia, Bamias, Giorgos, Siakavellas, Spyros I, Goukos, Dimitris, Karagiannakis, Dimitris, Zampeli, Evanthia, Vlachogiannakos, Jiannis, Michopoulos, Spyridon, Vafiadi, Irene, Daikos, George L, Ladas, Spiros D

“…Bacterial translocation (BT) commonly occurs in cirrhosis. Reliable biomarkers for BT are currently lacking. Human beta defensin-1 (hBD-1) is a member of the…”
Get full text

Genetic basis of aminoglycoside resistance following changes in aminoglycoside prescription patterns by Kosmidis, Chris, Giannopoulou, Maria, Flountzi, Anastasia, Markogiannakis, Antonis, Goukos, Dimitris, Petrikkos, George, Daikos, George L, Tzanetou, Konstantina

“…Aminoglycosides (AG) offer an important therapeutic option for the treatment of infections caused by multiresistant Enterobacteriaceae. We observed a change in…”
Get full text