Search Results - "Gough, K C"

The 'dark matter' of ubiquitin-mediated processes: opportunities and challenges in the identification of ubiquitin-binding domains by Radley, E H, Long, J, Gough, K C, Layfield, R

“…Ubiquitin modifications of target proteins act to localise, direct and specify a diverse range of cellular processes, many of which are biomedically relevant…”
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Prions Are Secreted in Milk from Clinically Normal Scrapie-Exposed Sheep by MADDISON, B. C, BAKER, C. A, REES, H. C, TERRY, L. A, THORNE, L, BELLWORTHY, S. J, WHITELAM, G. C, GOUGH, K. C

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An in vitro model for assessing effective scrapie decontamination by Gough, K.C., Baker, C.A., Maddison, B.C.

“…•Scrapie prions which have been shed from infected sheep and goats are extremely difficult to decontaminate within the farm environment.•Scrapie infectivity…”
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Generation and characterisation of monoclonal antibodies to Rainbow trout ( Oncorhynchus mykiss) prion protein by Maddison, B.C., Patel, S., James, R.F., Conlon, H.E., Oidtmann, B., Baier, M., Whitelam, G.C., Gough, K.C.

“…We report the production and characterisation of three monoclonal antibodies to the prion protein (PrP) of Rainbow trout ( Oncorhynchus mykiss), a piscine…”
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Does the Presence of Scrapie Affect the Ability of Current Statutory Discriminatory Tests To Detect the Presence of Bovine Spongiform Encephalopathy? by Simmons, M M, Chaplin, M J, Vickery, C M, Simon, S, Davis, L, Denyer, M, Lockey, R, Stack, M J, O'Connor, M J, Bishop, K, Gough, K C, Maddison, B C, Thorne, L, Spiropoulos, J

“…Current European Commission (EC) surveillance regulations require discriminatory testing of all transmissible spongiform encephalopathy (TSE)-positive small…”
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Cyanobacterial GR6 glutamate-1-semialdehyde aminotransferase : a novel enzyme-based selectable marker for plant transformation by GOUGH, K. C, HAWES, W. S, KILPATRICK, J, WHITELAM, G. C

“…The mutant glutamate-1-semialdehyde aminotransferase (GSA-AT) enzyme encoded by the hemL gene of the gabaculine-resistant cyanobacterium Synechococcus PCC6301…”
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Selection of phage-display peptides that bind to cucumber mosaic virus coat protein by Gough, Kevin C., Cockburn, William, Whitelam, Garry C.

“…Several discrete peptides that bind specifically to the coat protein of cucumber mosaic virus (CMV) were isolated from a diverse phage library displaying…”
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Selection of phage antibodies to surface epitopes of Phytophthora infestans by Gough, Kevin C, Li, Yi, Vaughan, Tristan J, Williams, Andrew J, Cockburn, William, Whitelam, Garry C

“…Antibodies specific for surface-exposed epitopes on germlings of the plant pathogen, Phytophthora infestans, were isolated from a diverse phage library…”
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Cellular prion protein in ovine milk by Maddison, Ben C., Whitelam, Garry C., Gough, Kevin C.

“…Cellular prion protein, PrP C, is essential for the development of prion diseases where it is considered to be a substrate for the formation of the…”
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Use of thermolysin in the diagnosis of prion diseases by OWEN, Jonathan P, MADDISON, Ben C, WHITELAM, Garry C, COUGH, Kevin C

“…The molecular diagnosis of prion diseases almost always involves the use of a protease to distinguish PrPC from PrPSc and invariably the protease of choice is…”
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Recombinant anti-EspA antibodies block Escherichia coli O157:H7-induced attaching and effacing lesions in vitro by La Ragione, Roberto M., Patel, Shila, Maddison, Ben, Woodward, Martin J., Best, Angus, Whitelam, Garry C., Gough, Kevin C.

“…Intimin and EspA proteins are virulence factors expressed by attaching and effacing Escherichia coli (AEEC) such as enteropathogenic and enterohaemorrhagic E…”
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Isolation of Recombinant Antibodies against EspA and Intimin of Escherichia coli O157:H7 by KÜHNE, Sarah A, HAWES, William S, RAGIONE, Roberto M, WOODWARD, Martin J, WHITELAM, Garry C, GOUGH, Kevin C

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Cyanobacterial GR6 glutamate-1-semialdehyde aminotransferase: a novel enzyme-based selectable marker for plant transformation by Gough, K.C., Hawes, W.S., Kilpatrick, J., Whitelam, G.C.

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