Search Results - "Gough, Gerald W."

Cell-mediated immune responses to COPV early proteins by Jain, Suchitra, Moore, Richard A., Anderson, Davina M., Gough, Gerald W., Stanley, Margaret A.

“…Cell-mediated immunity plays a key role in the regression of papillomavirus-induced warts and intra-epithelial lesions but the target antigens that induce this…”
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Therapeutic immunisation with COPV early genes by epithelial DNA delivery by Moore, Richard A, Walcott, Sarah, White, Kate L, Anderson, Davina M, Jain, Suchitra, Lloyd, Andrew, Topley, Peter, Thomsen, Lindy, Gough, Gerald W, Stanley, Margaret A

“…Following challenge with COPV (canine oral papillomavirus), DNA plasmids encoding COPV L1, E1 or E2 protein were delivered into oral mucosal and cutaneous…”
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Intraepithelial DNA Immunisation with a Plasmid Encoding a Codon Optimised COPV E1 Gene Sequence, But Not the Wild-Type Gene Sequence Completely Protects against Mucosal Challenge with Infectious COPV in Beagles by Moore, Richard A., Santos, Elmer B., Nicholls, Philip K., White, Kate L., Anderson, Davina M., Lloyd, Andrew, Topley, Peter, Romanos, Michael, Thomsen, Lindy, Parmar, Vanita, Walcott, Sarah, Gough, Gerald W., Stanley, Margaret A.

“…DNA plasmids encoding the open reading frames of canine oral papillomavirus (COPV) nonstructural early genes E1, E2, or E7 protein were delivered into both…”
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DNA bending induced by cruciform formation by Gough, Gerald W, Lilley, David M. J

“…Cruciform structures in DNA are of considerable interest, both as extreme examples of sequence-dependent structural heterogeneity and as models for four-way…”
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Localized chemical hyperreactivity in supercoiled DNA. Evidence for base unpairing in sequences that induce low-salt cruciform extrusion by Furlong, Judy C, Sullivan, Karen M, Murchie, Alastair I. H, Gough, Gerald W, Lilley, David M. J

“…Certain A + T-rich DNA sequences (C-type inducing sequences) cause adjacent inverted repeats to undergo cruciform extrusion by a particular pathway (C-type…”
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Regression of Canine Oral Papillomas Is Associated with Infiltration of CD4+ and CD8+ Lymphocytes by Nicholls, Philip K., Moore, Peter F., Anderson, Davina M., Moore, Richard A., Parry, Nigel R., Gough, Gerald W., Stanley, Margaret A.

“…Canine oral papillomavirus (COPV) infection is used in vaccine development against mucosal papillomaviruses. The predictable, spontaneous regression of the…”
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The physical chemistry of cruciform structures in supercoiled DNA molecules by Lilley, D M, Gough, G W, Hallam, L R, Sullivan, K M

“…Inverted repeat DNA sequences extrude cruciform structures when present in negatively supercoiled molecules, stabilised by the release of torsional stress…”
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Naturally Occurring, Nonregressing Canine Oral Papillomavirus Infection: Host Immunity, Virus Characterization, and Experimental Infection by Nicholls, Philip K., Klaunberg, Brenda A., Moore, Richard A., Santos, Elmer B., Parry, Nigel R., Gough, Gerald W., Stanley, Margaret A.

“…Papillomaviruses occasionally cause severe, nonregressing or recurrent infections in their human and animal hosts. The mechanisms underlying these atypical…”
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