Search Results - "Gouda, Mohamed"

Tumor-Agnostic Precision Medicine from the AACR GENIE Database: Clinical Implications by Gouda, Mohamed A, Nelson, Blessie E, Buschhorn, Lars, Wahida, Adam, Subbiah, Vivek

“…Biomarker-driven cancer therapy has revolutionized precision oncology. With a better understanding of tumor biology, tissue-agnostic targets have been…”
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Tissue-Agnostic Cancer Therapy Approvals by Gouda, Mohamed A., Subbiah, Vivek

“…Tumor-agnostic, or histology-agnostic, cancer therapy marks a groundbreaking evolution in the realm of precision oncology. In stark contrast to conventional…”
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N-of-1 Trials in Cancer Drug Development by Gouda, Mohamed A, Buschhorn, Lars, Schneeweiss, Andreas, Wahida, Adam, Subbiah, Vivek

“…The current approaches for cancer drug development lag behind an accelerated need in the field for a fast and efficient method for evaluating drugs in the…”
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Strategies for Mitigating Antibody-Drug Conjugate Related Adverse Events for Precision Therapy by Gouda, Mohamed A., Subbiah, Vivek

“…Abstract Antibody-drug conjugates (ADCs) have been revolutionary in improving personalized therapy of cancer. Through combining monoclonal antibodies, which…”
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Precision oncology with selective RET inhibitor selpercatinib in RET-rearranged cancers by Gouda, Mohamed A., Subbiah, Vivek

“…Rearranged during transfection (RET) is a protooncogene that encodes for receptor tyrosine kinase with downstream effects on multiple cellular pathways…”
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Combination of sodium alginate-based coating with L-cysteine and citric acid extends the shelf-life of fresh-cut lotus root slices by inhibiting browning and microbial growth by Bata Gouda, Mohamed Hawali, Zhang, Chunjie, Peng, Sijia, Kong, Xiaoxue, Chen, Yuru, Li, Hong, Li, Xuerui, Luo, Haibo, Yu, Lijuan

“…•SA + L-cys + CA inhibited the browning and microbial growth of lotus root slices.•Visual appearance, physicochemical and bacterial diversity were…”
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The evolving landscape of tissue‐agnostic therapies in precision oncology by Subbiah, Vivek, Gouda, Mohamed A., Ryll, Bettina, Burris, Howard A., Kurzrock, Razelle

“…ABSTRACT Tumor‐agnostic therapies represent a paradigm shift in oncology by altering the traditional means of characterizing tumors based on their origin or…”
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As-is facility management approach using LiDAR-based building information modelling: a case study in Egypt by Gouda Mohamed, Ahmed, Mousa, Amr

“…Purpose Current research efforts exhibit a surge imperative for a building information modelling (BIM) approach that embodies a repository of all relevant data…”
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Predictive Significance of Combined Plasmatic Detection of BRAF Mutations and S100B Tumor Marker in Early‐Stage Malignant Melanoma by Polivka, Jiri, Gouda, Mohamed A., Sharif, Mahyar, Pesta, Martin, Huang, Helen, Treskova, Inka, Woznica, Vlastimil, Windrichova, Jindra, Houfkova, Katerina, Kucera, Radek, Fikrle, Tomas, Ricar, Jan, Pivovarcikova, Kristyna, Topolcan, Ondrej, Janku, Filip

“…ABSTRACT Background Melanoma is the most aggressive skin cancer with ability to recur also after early‐stage tumor surgery. The aim was to identify early‐stage…”
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Design, Synthesis, Spectroscopic Inspection, DFT and Molecular Docking Study of Metal Chelates Incorporating Azo Dye Ligand for Biological Evaluation by Al-Gaber, Mohamed Ali Ibrahim, Abd El-Lateef, Hany M, Khalaf, Mai M, Shaaban, Saad, Shawky, Mohamed, Mohamed, Gehad G, Abdou, Aly, Gouda, Mohamed, Abu-Dief, Ahmed M

“…A new heterocyclic azo dye ligand (L) was synthesized by the combination of 4-amino antipyrine with 4-aminophenol. The new Cr(III), Mn(II), Fe(III), Co(II),…”
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Carboxymethyl Cellulose/Zn-Organic Framework Down-Regulates Proliferation and Up-Regulates Apoptosis and DNA Damage in Colon and Lung Cancer Cell Lines by Negm, Amr, Gouda, Mohamed, Ibrahim, Hairul-Islam M

“…A solvothermal technique was used to prepare a Zn-benzenetricarboxylic acid (Zn@BTC) organic framework covered with a carboxymethyl cellulose (CMC/Zn@BTC)…”
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Expanding the Benefit: Dabrafenib/Trametinib as Tissue-Agnostic Therapy for BRAF V600E-Positive Adult and Pediatric Solid Tumors by Gouda, Mohamed A, Subbiah, Vivek

“…The recent US Food and Drug Administration (FDA) approval of the dabrafenib/trametinib combination as a tissue-agnostic treatment for solid tumors with V600E…”
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Building condition assessment using artificial neural network and structural equations by Gouda Mohamed, Ahmed, Marzouk, Mohamed

“…•Present a physical condition assessment model for existing educational buildings.•Predict the future condition data of building components via an ANN and SEM…”
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Tissue-Agnostic Targeting of Neurotrophic Tyrosine Receptor Kinase Fusions: Current Approvals and Future Directions by Gouda, Mohamed A, Thein, Kyaw Z, Hong, David S

“…fusions are oncogenic drivers for multiple tumor types. Therefore, the development of selective tropomyosin receptor kinase (TRK) inhibitors, including…”
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The Landscape of Alterations from 1407 Ultra-Rare Sarcomas from the AACR GENIE Database: Clinical Implications by Denu, Ryan A, Moyers, Justin T, Gouda, Mohamed A, Conley, Anthony P, Lazar, Alexander J, Subbiah, Vivek

“…Ultra-rare sarcomas (URS) comprise a group of orphan diseases with an incidence of ≤1/1,000,000 people per year. We aimed to assess clinically actionable…”
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OP-095 [AJC » Cardiac imaging - Echocardiography] Effect of Diabetic Duration on Left Ventricular Global Longitudinal Strain by Speckle Tracking Imaging by Elgohary, Ahmed Abdelwahab, Shalaby, Mohamed Anwar, Mahfouz, Ragab Abdelsalam, Mohamed, Mohamed Gouda

“…Speckle tracking is more sensitive than LVEF in detection subclinical LV systolic dysfunction However, it is not clear whether there is any difference in early…”
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Exportin(g) precision oncology beyond genomics with XPO1 inhibition by Gouda, Mohamed A, Subbiah, Vivek

“…We urgently need to identify new druggable targets for pediatric cancers. Coutinho et al. identified and validated XPO1 aberrant activity in patients with…”
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Surgical treatment of sacroiliac joint infection by Ahmed, Hamdan, Siam, Ahmed Ezzat, Gouda-Mohamed, Gouda-Mohamed, Boehm, Heinrich

“…Background Sacroiliac joint infection is rare and frequently missed; purpose of this study is to describe the clinical presentations, comorbidities, laboratory…”
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Synthesis, DFT, Biological and Molecular Docking Analysis of Novel Manganese(II), Iron(III), Cobalt(II), Nickel(II), and Copper(II) Chelate Complexes Ligated by 1-(4-Nitrophenylazo)-2-naphthol by Alghuwainem, Yousef A A, El-Lateef, Hany M Abd, Khalaf, Mai M, Amer, Amer A, Abdelhamid, Antar A, Alzharani, Ahmed A, Alfarsi, Anas, Shaaban, Saad, Gouda, Mohamed, Abdou, Aly

“…Novelmanganese(II), iron(III), cobalt(II), nickel(II), and copper(II) chelates were synthesized and studied using elemental analysis (EA), infrared…”
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BIM and semantic web-based maintenance information for existing buildings by Gouda Mohamed, Ahmed, Abdallah, Mohamed Reda, Marzouk, Mohamed

“…In the existing building facilities context, the BIM substantial intervention concerning semantics and as-is information based portrayal for maintenance…”
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