Search Results - "Goubern, M."
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A marketed fermented dairy product containing Bifidobacterium lactis CNCM I-2494 suppresses gut hypersensitivity and colonic barrier disruption induced by acute stress in rats
Published in Journal of neurogastroenterology and motility (01-04-2012)“…Background Fermented milk (FM) containing Bifidobacterium lactis CNCM I‐2494 and yogurt strains improves irritable bowel syndrome (IBS) symptoms in…”
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tBid interaction with cardiolipin primarily orchestrates mitochondrial dysfunctions and subsequently activates Bax and Bak
Published in Cell death and differentiation (01-06-2005)“…TNFR1/Fas engagement results in the cleavage of cytosolic Bid to truncated Bid (tBid), which translocates to mitochondria. We demonstrate that recombinant tBid…”
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Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production
Published in Nature genetics (01-12-2000)“…The gene Ucp2 is a member of a family of genes found in animals and plants, encoding a protein homologous to the brown fat uncoupling protein Ucp1 (refs 1-3)…”
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Adaptative metabolic response of human colonic epithelial cells to the adverse effects of the luminal compound sulfide
Published in Biochimica et biophysica acta (15-09-2005)“…Hydrogen sulfide (H 2S), a bacterial metabolite present in the lumen of the large intestine, is able to exert deleterious effects on the colonic epithelium…”
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No Evidence for a Basal, Retinoic, or Superoxide-induced Uncoupling Activity of the Uncoupling Protein 2 Present in Spleen or Lung Mitochondria
Published in The Journal of biological chemistry (19-07-2002)“…The phenotypes observed in mice whose uncoupling protein (Ucp2) gene had been invalidated by homologous recombination (Ucp2(−/−) mice) are consistent with an…”
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Disruption of the outer mitochondrial membrane as a result of large amplitude swelling: the impact of irreversible permeability transition
Published in FEBS letters (10-04-1998)“…Upon induction of permeability transition with different agents (Ca 2+, tert-butyl hydroperoxide, atractyloside), mouse hepatocyte mitochondria manifest a…”
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Retinoids activate proton transport by the uncoupling proteins UCP1 and UCP2
Published in The EMBO journal (01-11-1999)“…In mammalian brown adipose tissue, thermogenesis is explained by uncoupling mitochondrial respiration from ATP synthesis. Uncoupling protein‐1 (UCP1) is…”
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Long term treatment with olanzapine mixed with the food in male rats induces body fat deposition with no increase in body weight and no thermogenic alteration
Published in Appetite (01-05-2006)“…Body weight gain is a worrying side effect of many new antipsychotic drugs. The mechanisms by which antipsychotic drugs increase weight in humans are not…”
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Circadian rhythm and hormonal sensitivity of lipoprotein lipase activity in cold acclimated rats
Published in Hormone and metabolic research (01-02-1981)“…To delineate the factors that may affect triglyceride capture in brown adipose tissue, we have determined the lipoprotein lipase activity (LPS) under…”
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BMCP1, a Novel Mitochondrial Carrier with High Expression in the Central Nervous System of Humans and Rodents, and Respiration Uncoupling Activity in Recombinant Yeast
Published in The Journal of biological chemistry (18-12-1998)“…We report here the cloning and functional analysis of a novel homologue of the mitochondrial carriers predominantly expressed in the central nervous system and…”
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Effect of acute magnesium deficiency on the masking and unmasking of the proton channel of the uncoupling protein in rat brown fat
Published in Magnesium research (01-06-1993)“…The short term regulation of heat production in brown adipose tissue mitochondria (BAT) of acutely Mg-deficient rats was demonstrated by comparing several…”
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The effects of essential fatty acid deficiency on brown adipose tissue activity in rats maintained at thermal neutrality
Published in Comparative biochemistry and physiology. A, Comparative physiology (1989)“…1. The consequences of essential fatty acid (EFA) deficiency on the resting metabolism, food efficiency and brown adipose tissue (BAT) thermogenic activity…”
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Concomitant food intake and adipose tissue responses under chronic insulin infusion in rats
Published in Physiology & behavior (1988)“…Body weight (BW), food intake (FI), and activity of white adipose tissue (WAT) and brown adipose tissue (BAT) were studied in adult male rats under chronic…”
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Magnesium and thermoregulation. I. Newborn and infant. Is sudden infant death syndrome a magnesium-dependent disease of the transition from chemical to physical thermoregulation?
Published in Magnesium research (01-09-1991)“…The sudden infant death syndrome (SIDS) remains a leading cause of death during the first year. The common epidemiological and pathological data which…”
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Intraperitoneal leptin modifies macronutrient choice in self-selecting rats
Published in Physiology & behavior (30-10-2004)“…This study aimed to evaluate the consequences on food intake and body weight (BW) of leptin administration in rats receiving a choice between the three…”
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Thermogenesis and brown adipose tissue activity in high fat fed Osborne-Mendel rats
Published in Annals of nutrition and metabolism (1988)“…The consequences of hyperlipidic feeding on interscapular brown adipose tissue (IBAT) activity were examined in the cold-acclimated rat. Male Osborne-Mendel…”
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High Level of Uncoupling Protein 1 Expression in Muscle of Transgenic Mice Selectively Affects Muscles at Rest and Decreases Their IIb Fiber Content
Published in The Journal of biological chemistry (08-11-2002)“…The mitochondrial uncoupling protein of brown adipose tissue (UCP1) was expressed in skeletal muscle and heart of transgenic mice at levels comparable with the…”
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Effect of temperature on lipoprotein lipase and lipogenic enzyme activities in brown adipose tissue of hypophysectomized rats
Published in Hormone and metabolic research (01-04-1985)“…It has been shown that the same modifications on the composition of brown adipose tissue (BAT) which are normally induced following cold stimulation are also…”
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Effect of environmental temperature on dietary obesity in Osborne-Mendel rats
Published in Annals of nutrition and metabolism (1988)“…The effects of cold acclimation on cellularity, lipoprotein lipase (LPL) activity and lipolysis were studied in white adipose tissue of rats fed a high fat…”
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