Factors associated with complications in ST-elevation myocardial infarction: a single-center experience

Background ST-elevation myocardial infarction (STEMI) is a major public health problem. This study aimed to determine the prevalence and identify the determinants of STEMI-related complications in the Cardiology Intensive Care Unit of the Sud Francilien Hospital Center (SFHC). Methods We retrospecti...

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Published in:	BMC cardiovascular disorders Vol. 23; no. 1; pp. 1 - 468
Main Authors:	Mavungu Mbuku, Jean-Michel, Mukombola Kasongo, Aldophe, Goube, Pascale, Miltoni, Laetitia, Nkodila Natuhoyila, Aliocha, M'Buyamba-Kabangu, Jean-Réné, Longo-Mbenza, Benjamin, Kianu Phanzu, Bernard
Format:	Journal Article
Language:	English
Published:	London BioMed Central Ltd 19-09-2023 BioMed Central BMC
Subjects:	Acute coronary syndromes Analysis Atrial fibrillation Blood pressure Cardiac patients Cardiology Cerebral infarction Cholesterol Cigarette smoking Complications Complications and side effects Congestive heart failure Coronary vessels Coronaviruses COVID-19 Creatinine Determinants Diabetes Diabetes mellitus Ejection fraction Fibrillation Frequency Heart attack Heart attacks Heart failure Heart rate Heart surgery High density lipoprotein Hospitals Hypertension Ischemia Kidney diseases Low density lipoprotein Medical records Metabolic disorders Mortality Myocardial infarction Public health Pulmonary embolisms Smoking STEMI Stroke Stroke (Disease) Sud Francilien Hospital Center Transient ischemic attack Veins & arteries France
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Summary:	Background ST-elevation myocardial infarction (STEMI) is a major public health problem. This study aimed to determine the prevalence and identify the determinants of STEMI-related complications in the Cardiology Intensive Care Unit of the Sud Francilien Hospital Center (SFHC). Methods We retrospectively analyzed the data of 315 patients with STEMI aged [greater than or equal to] 18 years. Logistic regression was used to identify factors independently associated with the occurrence of complications. Results Overall, 315 patients aged 61.7 [+ or -] 13.4 years, of whom 261 were men, had STEMI during the study period. The hospital frequency of STEMI was 12.7%. Arrhythmias and acute heart failure were the main complications. Age [greater than or equal to] 75 years (adjusted odds ratio [aOR], 5.18; 95% confidence interval [CI], 3.92-8.75), hypertension (aOR, 3.38; 95% CI, 1.68-5.82), and cigarette smoking (aOR, 3.52; 95% CI, 1.69-7.33) were independent determinants of acute heart failure. Meanwhile, diabetes mellitus (aOR, 1.74; 95% CI, 1.09-3.37), history of atrial fibrillation (aOR, 2.79; 95% CI, 1.66-4.76), history of stroke or transient ischemic attack (aOR, 1.99; 95% CI, 1.31-2.89), and low high-density lipoprotein-cholesterol (HDL-C) levels (aOR, 3.70; 95% CI, 1.08-6.64) were independent determinants of arrhythmias. Conclusion STEMI is a frequent condition at SFHC and is often complicated by acute heart failure and arrhythmias. Patients aged [greater than or equal to] 75 years, those with hypertension or diabetes mellitus, smokers, those with a history of atrial fibrillation or stroke, and those with low HDL-C levels require careful monitoring for the early diagnosis and management of these complications. Keywords: STEMI, Frequency, Determinants, Complications, Sud Francilien Hospital Center
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1471-2261 1471-2261
DOI:	10.1186/s12872-023-03498-z