Search Results - "Gou, Xingchun"

Astrocyte Senescence and Alzheimer’s Disease: A Review by Han, Xiaojuan, Zhang, Tianying, Liu, Huanhuan, Mi, Yajing, Gou, Xingchun

“…Astrocytes represent the largest group of glial cells and participate in a variety of essential functions in the healthy central nervous system (CNS)…”
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Cytokine-Induced Killer Cells As Pharmacological Tools for Cancer Immunotherapy by Gao, Xingchun, Mi, Yajing, Guo, Na, Xu, Hao, Xu, Lixian, Gou, Xingchun, Jin, Weilin

“…Cytokine-induced killer (CIK) cells are a heterogeneous population of effector CD3 CD56 natural killer T cells, which can be easily expanded from peripheral…”
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The Emerging Roles of Ferroptosis in Huntington’s Disease by Mi, Yajing, Gao, Xingchun, Xu, Hao, Cui, Yuanyuan, Zhang, Yuelin, Gou, Xingchun

“…Huntington’s disease (HD) is an autosomal dominant and fatal neurodegenerative disorder, which is caused by an abnormal CAG repeat in the huntingtin gene…”
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Potential regulators of the senescence-associated secretory phenotype during senescence and ageing by Han, Xiaojuan, Lei, Qing, Xie, Jiamei, Liu, Huanhuan, Sun, Haoran, Jing, Li, Zhang, Xiaohua, Zhang, Tianying, Gou, Xingchun

“…Senescent cells express and secrete a variety of extracellular modulators that include cytokines, chemokines, proteases, growth factors and some enzymes…”
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Thrombin-Responsive, Brain-Targeting Nanoparticles for Improved Stroke Therapy by Guo, Xing, Deng, Gang, Liu, Jun, Zou, Pan, Du, Fengyi, Liu, Fuyao, Chen, Ann T, Hu, Rui, Li, Miao, Zhang, Shenqi, Tang, Zhishu, Han, Liang, Liu, Jie, Sheth, Kevin N, Chen, Qianxue, Gou, Xingchun, Zhou, Jiangbing

“…Current treatments for ischemic stroke are insufficient. The lack of effective pharmacological approaches can be mainly attributed to the difficulty in…”
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Targeted drug delivery to ischemic stroke via chlorotoxin-anchored, lexiscan-loaded nanoparticles by Han, Liang, PhD, Cai, Qiang, MD, Tian, Daofeng, MD, Kong, Derek K., MS, Gou, Xingchun, PhD, Chen, Zeming, BS, Strittmatter, Stephen M., MD, PhD, Wang, Zuoheng, PhD, Sheth, Kevin N., MD, Zhou, Jiangbing, PhD

“…Abstract Ischemic stroke is a leading cause of disability and death worldwide. Current drug treatment for stroke remains inadequate due to the existence of the…”
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Berberine induces cell death in human hepatoma cells in vitro by downregulating CD147 by Hou, Qian, Tang, Xu, Liu, Hanqiang, Tang, Junqi, Yang, Ying, Jing, Xiaohong, Xiao, Qian, Wang, Wen, Gou, Xingchun, Wang, Zongren

“…The isoquinoline plant alkaloid berberine has anti‐tumor effects on a variety of carcinoma cells, mainly through inhibition of cell proliferation, apoptosis…”
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SLFN11 is a general target for enhancing the sensitivity of cancer to chemotherapy (DNA-damaging agents) by Luan, Jing, Gao, Xingchun, Hu, Fengrui, Zhang, Yuelin, Gou, Xingchun

“…In patients with cancer, drug tolerance often occurs during the use of chemotherapy drugs, seriously affecting patient prognosis and survival. Therefore,…”
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Analysis of the dynamic changes in the proportion of immune cells and the proportion of cells with stem cell characteristics in the corresponding immune cell population of C57 mice during the natural aging process by Luan, Jing, Xu, Hao, Jin, Zhang, Guan, Hua, Gao, Xingchun, Gou, Xingchun, Xu, Lixian

“…The aging of the immune system is not only an inevitable result but also an important cause of physical aging. The aging of the immune system is rooted in the…”
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Is Plant Sterols a Good Strategy to Lower Cholesterol? by Chen, Yuwei, She, Yongbo, Kaur, Ramandeep, Guo, Na, Zhang, Xiaohua, Zhang, Ruisan, Gou, Xingchun

“…Cardiovascular disease (CVD) has emerged as the leading cause of dealth worldwide today. Lowering circulating total cholesterol (TC) and low density…”
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Secreted Frizzled Related Proteins in Cardiovascular and Metabolic Diseases by Guan, Hua, Zhang, Jin, Luan, Jing, Xu, Hao, Huang, Zhenghao, Yu, Qi, Gou, Xingchun, Xu, Lixian

“…Abnormal gene expression and secreted protein levels are accompanied by extensive pathological changes. Secreted frizzled related protein (SFRP) family members…”
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Design, synthesis, and biological evaluation of novel androst-17β-amide structurally related compounds as dual 5α-reductase inhibitors and androgen receptor antagonists by Lao, Kejing, Xun, Guoliang, Gou, Xingchun, Xiang, Hua

“…Prostate cancer (PCa) is the second leading cause of death in men. Apart from androgen receptor, 5α-reductase has also been recognized as a potential target…”
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CDK-associated Cullin 1 Promotes Cell Proliferation and Inhibits Cell Apoptosis in Human Glioblastoma by Zhang, Xiaohua, Zhang, Tianying, Han, Xiaojuan, Qiu, Zhongying, Cheng, Jianghong, Gao, Xingchun, Gou, Xingchun

“…Glioma is the most common intracranial primary tumour of adult humans, and its pathological mechanism and molecular characteristics are still under…”
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TAT-PEP Enhanced Neurobehavioral Functional Recovery by Facilitating Axonal Regeneration and Corticospinal Tract Projection After Stroke by Deng, Bin, Li, Liya, Gou, Xingchun, Xu, Hao, Zhao, Zhaohua, Wang, Qiang, Xu, Lixian

“…Paired immunoglobulin-like receptor B (PirB) has been identified as a new receptor for myelin-associated inhibitory (MAI) proteins, which may play important…”
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Human tumor cells induce angiogenesis through positive feedback between CD147 and insulin-like growth factor-I by Chen, Yanke, Gou, Xingchun, Ke, Xia, Cui, Hongyong, Chen, Zhinan

“…Tumor angiogenesis is a complex process based upon a sequence of interactions between tumor cells and endothelial cells. Previous studies have shown that CD147…”
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Pretreatment With Electroacupuncture Induces Rapid Tolerance to Focal Cerebral Ischemia Through Regulation of Endocannabinoid System by Wang, Qiang, Peng, Ye, Chen, Shaoyang, Gou, Xingchun, Hu, Bo, Du, Juan, Lu, Yan, Xiong, Lize

“…Our previous study demonstrated that pretreatment with electroacupuncture (EA) induces rapid tolerance to focal cerebral ischemia. The present study was aimed…”
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Suppression of Tumorigenicity 5 Ameliorates Tumor Characteristics of Invasive Breast Cancer Cells via ERK/JNK Pathway by Cheng, Jianghong, Li, Mingli, Tzeng, Chi-Meng, Gou, Xingchun, Chen, Shuai

“…Suppression of tumorigenicity 5 (ST5) has been considered as a tumor suppressor gene in HeLa tumor cells. However, its role in the progression of breast cancer…”
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Comparative mitochondrial genomes of four species of Sinopodisma and phylogenetic implications (Orthoptera, Melanoplinae) by Zhongying, Qiu, Huihui, Chang, Hao, Yuan, Yuan, Huang, Huimeng, Lu, Xia, Li, Xingchun, Gou

“…In this study, the whole mitochondrial genomes (mitogenomes) from four species were sequenced. The complete mitochondrial genomes of , , , and are 15,857 bp,…”
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High-Quality Genome Assembly of Chrysaora quinquecirrha Provides Insights Into the Adaptive Evolution of Jellyfish by Xia, Wangxiao, Li, Haorong, Cheng, Wenmin, Li, Honghui, Mi, Yajing, Gou, Xingchun, Liu, Yaowen

“…Jellyfish, such as Chrysaora quinquecirrha , hold an important evolutionary position and have great ecological value. However, limited genomic resources are…”
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TAT‐LBD‐Ngn2‐improved cognitive functions after global cerebral ischemia by enhancing neurogenesis by Feng, Bin, Jia, Sansan, Li, Liya, Wang, Jiajia, Zhou, Fang, Gou, Xingchun, Wang, Qiang, Xiong, Lize, Zeng, Yi, Zhong, Haixing

“…Background Stroke is the major cause of adult neurocognitive disorders (NCDs), and presents a significant burden on both of the families and society. To…”
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