Search Results - "Gou, Xiaojun"

Therapeutic effect of Sanhua decoction on rats with middle cerebral artery occlusion and the associated changes in gut microbiota and short-chain fatty acids by Ni, Yiming, Cai, Liangyin, Gou, Xiaojun, Li, Wenjie, Zhou, Mingmei, Huang, Ying

“…Sanhua decoction (SHD), a traditional prescription, has long been used in treating ischemic stroke (IS). However, the therapeutic effect of SHD and the…”
Get full text

Plant-derived bioactive compounds regulate the NLRP3 inflammasome to treat NAFLD by Huang, Qian, Xin, Xin, Sun, QinMei, An, Ziming, Gou, Xiaojun, Feng, Qin

“…Non-alcoholic fatty liver disease (NAFLD) is a liver disorder characterized by abnormal accumulation of hepatic fat and inflammatory response with complex…”
Get full text

Brain and serum metabolomic studies reveal therapeutic effects of san hua decoction in rats with ischemic stroke by Liu, Ruisi, Cao, Shengxuan, Cai, Yufeng, Zhou, Mingmei, Gou, Xiaojun, Huang, Ying

“…San Hua Decoction (SHD) is a traditional four-herbal formula that has long been used to treat stroke. Our study used a traditional pharmacodynamic approach…”
Get full text

Qushi Huayu decoction ameliorates non-alcoholic fatty liver disease in rats by modulating gut microbiota and serum lipids by Ni, Yiming, Wang, Xin, Wu, Qian, Yao, Yichen, Xu, Yuan, Li, Yuanyuan, Feng, Qin, Zhou, Mingmei, Gou, Xiaojun

“…Introduction Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disease. As a clinical empirical prescription of traditional Chinese medicine, Qushi…”
Get full text

PD-L1 Nanobody Competitively Inhibits the Formation of the PD-1/PD-L1 Complex: Comparative Molecular Dynamics Simulations by Sun, Xin, Yan, Xiao, Zhuo, Wei, Gu, Jinke, Zuo, Ke, Liu, Wei, Liang, Li, Gan, Ya, He, Gang, Wan, Hua, Gou, Xiaojun, Shi, Hubing, Hu, Jianping

“…The anti-PD-L1 monoclonal antibody (mAb) targeting PD-1/PD-L1 immune checkpoint has achieved outstanding results in clinical application and has become one of…”
Get full text

Investigation of Gynura segetum root extract (GSrE) induced hepatotoxicity based on metabolomic signatures and microbial community profiling in rats by Gu, Xinyi, Li, Shuwei, Lu, Mengna, Li, Ying, Wang, Qixue, Chen, Long, Jia, Yiqun, Cao, Shan, Zhang, Ting, Zhou, Mingmei, Gou, Xiaojun

“…In recent years, many reports focus on the hepatotoxicity of Gynura segetum root extract (GSrE), but the interaction between GSrE and the gut microbiota is…”
Get full text

Danggui-Shaoyao-San protects against non-alcoholic steatohepatitis via modulation of hepatic APP protein, Lysosomal CTSB release, and NF-κB activation by Gao, Siting, An, Ziming, Zhang, Qian, Sun, Qinmei, Huang, Qian, Shi, Lei, Liu, Wei, Gou, Xiaojun, Li, Yajuan, Xin, Xin, Feng, Qin

“…Non-alcoholic steatohepatitis (NASH), an escalating global health concern, is a primary factor behind cirrhosis, liver transplantation, and hepatocellular…”
Get full text

Rice choline monooxygenase (OsCMO) protein functions in enhancing glycine betaine biosynthesis in transgenic tobacco but does not accumulate in rice (Oryza sativa L. ssp. japonica) by Luo, Di, Niu, Xiangli, Yu, Jinde, Yan, Jun, Gou, Xiaojun, Lu, Bao-Rong, Liu, Yongsheng

“…Glycine betaine (GB) is a compatible quaternary amine that enables plants to tolerate abiotic stresses, including salt, drought and cold. In plants, GB is…”
Get full text

Tissue-Specific Distribution and Activity of Glutathione S-Transferases as Biomarkers in Bivalve Shellfishes by Wu, Xiaoyong, Liu, Wei, Gou, Xiaojun

“…In order to find the relationship between tissue-specific expressions of glutathione S-transferases (GSTs) and their function in preventing effects of…”
Get full text

Hierarchical Porous Protein Scaffold Templated from High Internal Phase Emulsion Costabilized by Gelatin and Gelatin Nanoparticles by Tan, Huan, Tu, Zhao, Jia, Hongqian, Gou, Xiaojun, Ngai, To

“…Recently, three-dimensional (3D) scaffolds produced using poly-Pickering high internal phase emulsions (polyHIPEs) technology are particularly attractive in…”
Get full text

Adsorption and removal of rhodamine B from aqueous solution by tannic acid functionalized graphene by Liu, Kunping, Li, Huiming, Wang, Yimin, Gou, Xiaojun, Duan, Yixiang

“…•Tannic acid functionalized graphene (TA-G) was synthesized.•TA-G exhibited fine adsorption performance for RB.•Theoretical maximum adsorption capacity of RB…”
Get full text

Gelatin Particle-Stabilized High-Internal Phase Emulsions for Use in Oral Delivery Systems: Protection Effect and in Vitro Digestion Study by Tan, Huan, Zhao, Lifeng, Tian, Sisi, Wen, Hui, Gou, Xiaojun, Ngai, To

“…The potential application of Pickering high-internal phase emulsions (HIPEs) in the food and pharmaceutical industries has yet to be fully developed. Herein,…”
Get full text

Ruthenium(II)‐Catalyzed C−H Chalcogenation of Anilides by Ma, Wenbo, Weng, Zhengyun, Rogge, Torben, Gu, Linghui, Lin, Jiafu, Peng, Ai, Luo, Xiang, Gou, Xiaojun, Ackermann, Lutz

“…Ruthenium‐catalyzed C−H chalcogenations of anilides with readily available diselenides and disulfides have been achieved. Our strategy features ample substrate…”
Get full text

JAK/STAT3 and Smad3 activities are required for the wound healing properties of Periplaneta americana extracts by Song, Qin, Xie, Yuxin, Gou, Qiheng, Guo, Xiaoqiang, Yao, Qian, Gou, Xiaojun

“…Periplaneta americana extracts (PAEs) play a crucial role in skin wound healing. However, their molecular effects and signaling pathways in regenerating…”
Get full text

Facile synthesis and characterization of indene-fused 4-methylcoumarins and an unexpected skeletal rearrangement via Pechmann condensation by Wu, Jie, Liu, Wei, Liang, Li, Gan, Ya, Xia, Shuang, Gou, Xiaojun, Sun, Xiaohua

“…[Display omitted] •The facile synthesis of indene-fused 4-methylcoumarins.•The observation of a fluorene skeletal rearrangement during the Pechmann…”
Get full text

Synthesis and characterization of a photoresponsive doxorubicin/combretastatin A4 hybrid prodrug by Liu, Wei, Liang, Li, Zhao, Lifeng, Tan, Huan, Wu, Jie, Qin, Qihui, Gou, Xiaojun, Sun, Xiaohua

“…[Display omitted] To explore the application of photoremovable protecting groups (PPGs) in the field of combination chemotherapy, we designed and synthesized a…”
Get full text

A highly selective pyrene based fluorescent sensor toward Hg2+ detection by Yang, Yang, Gou, Xiaojun, Blecha, John, Cao, Haishi

Get full text

3D-QSAR, Molecular Docking and Molecular Dynamics Simulation of Pseudomonas aeruginosa LpxC Inhibitors by Zuo, Ke, Liang, Li, Du, Wenyi, Sun, Xin, Liu, Wei, Gou, Xiaojun, Wan, Hua, Hu, Jianping

“…As an important target for the development of novel antibiotics, UDP-3- -( -3-hydroxymyristoyl)- -acetylglucosamine deacetylase (LpxC) has been widely studied…”
Get full text

RNAi-directed downregulation of betaine aldehyde dehydrogenase 1 (OsBADH1) results in decreased stress tolerance and increased oxidative markers without affecting glycine betaine biosynthesis in rice (Oryza sativa) by Tang, Wei, Sun, Jiaqi, Liu, Jia, Liu, Fangfang, Yan, Jun, Gou, Xiaojun, Lu, Bao-Rong, Liu, Yongsheng

“…As an important osmoprotectant, glycine betaine (GB) plays an essential role in resistance to abiotic stress in a variety of organisms, including rice (Oryza…”
Get full text

A urinary metabolomics (GC-MS) strategy to evaluate the antidepressant-like effect of chlorogenic acid in adrenocorticotropic hormone-treated rats by Zhao, Le, Zhang, Zixu, Zhou, Mingmei, Gou, Xiaojun, Zeng, Yang, Song, Jing, Ma, Weini, Xu, Ying

“…Major depressive disorder (MDD) is a chronic recurring illness that seriously affects human health. Chlorogenic acid (CGA), an important polyphenol extracted…”
Get full text