Search Results - "Gou, Kun"

An analytic study on nonlinear radius change for hyperelastic tubular organs under volume expansion by Gou, Kun, Muddamallappa, Mallikarjunaiah S.

“…Tubular organs with multilayers are common in human bodies and important for maintaining normal lives by transporting fluid, nutrient, or waste throughout the…”
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Biophysical and biochemical properties of PHGDH revealed by studies on PHGDH inhibitors by Tan, Yuping, Zhou, Xia, Gong, Yanqiu, Gou, Kun, Luo, Youfu, Jia, Da, Dai, Lunzhi, Zhao, Yinglan, Sun, Qingxiang

“…The rate-limiting serine biogenesis enzyme PHGDH is overexpressed in cancers. Both serine withdrawal and genetic/pharmacological inhibition of PHGDH have…”
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Effect of degree of deprotonation of maleic anhydride‐allyl polyethoxy carboxylic acid copolymer on calcium scale by Wang, Liang‐Chen, Zhao, Wei‐Dong, Che, Yao, Gou, Rui‐Kun, Liu, Hong‐Bin, Zhu, Chen‐Guo, Wang, Liang‐Bi, Guan, Zhi

“…A hydrophilic copolymer (MA‐APEA) containing carboxylic acid group and ethylene oxide group is synthesized from maleic anhydride (MA) and allyloxy polyethoxy…”
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DHODH and cancer: promising prospects to be explored by Zhou, Yue, Tao, Lei, Zhou, Xia, Zuo, Zeping, Gong, Jin, Liu, Xiaocong, Zhou, Yang, Liu, Chunqi, Sang, Na, Liu, Huan, Zou, Jiao, Gou, Kun, Yang, Xiaowei, Zhao, Yinglan

“…Human dihydroorotate dehydrogenase (DHODH) is a flavin-dependent mitochondrial enzyme catalyzing the fourth step in the de novo pyrimidine synthesis pathway…”
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Growth-profile configuration for specific deformations of tubular organs: A study of growth-induced thinning and dilation of the human cervix by Gou, Kun, Baek, Seungik, Lutnesky, Marvin M F, Han, Hai-Chao

“…Growth is a significant factor that results in deformations of tubular organs, and particular deformations associated with growth enable tubular organs to…”
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Repression of LSD1 potentiates homologous recombination-proficient ovarian cancer to PARP inhibitors through down-regulation of BRCA1/2 and RAD51 by Tao, Lei, Zhou, Yue, Pan, Xiangyu, Luo, Yuan, Qiu, Jiahao, Zhou, Xia, Chen, Zhiqian, Li, Yan, Xu, Lian, Zhou, Yang, Zuo, Zeping, Liu, Chunqi, Wang, Liang, Liu, Xiaocong, Tian, Xinyu, Su, Na, Yang, Zhengnan, Zhang, Yu, Gou, Kun, Sang, Na, Liu, Huan, Zou, Jiao, Xiao, Yuzhou, Zhong, Xi, Xu, Jing, Yang, Xinyu, Xiao, Kai, Liu, Yanyang, Yang, Shengyong, Peng, Yong, Han, Junhong, Cen, Xiaobo, Zhao, Yinglan

“…Poly (ADP-ribose) polymerase inhibitors (PARPi) are selectively active in ovarian cancer (OC) with homologous recombination (HR) deficiency (HRD) caused by…”
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Epigenetic regulation in cancer therapy: From mechanisms to clinical advances by Tao, Lei, Zhou, Yue, Luo, Yuan, Qiu, Jiahao, Xiao, Yuzhou, Zou, Jiao, Zhang, Yu, Liu, Xingchen, Yang, Xinyu, Gou, Kun, Xu, Jing, Guan, Xinqi, Cen, Xiaobo, Zhao, Yinglan

“…Epigenetic regulation refers to the alteration of gene expression independent of changes in DNA sequence. It involves chemical modifications such as DNA…”
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Numerical solution of the Goursat problem on a triangular domain with mixed boundary conditions by Gou, Kun, Sun, Bo

“…For the Goursat problem, we consider a triangular domain with mixed Dirichlet and impedance boundary conditions imposed on it. We develop an algorithm for its…”
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Mechanics of morphogenesis in neural development: In vivo, in vitro, and in silico by Sutlive, Joseph, Seyyedhosseinzadeh, Hamed, Ao, Zheng, Xiu, Haning, Choudhury, Sangita, Gou, Kun, Guo, Feng, Chen, Zi

“…Morphogenesis in the central nervous system has received intensive attention as elucidating fundamental mechanisms of morphogenesis will shed light on the…”
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A novel and potent dihydroorotate dehydrogenase inhibitor suppresses the proliferation of colorectal cancer by inducing mitochondrial dysfunction and DNA damage by Yang, Xiaowei, Li, Chungen, Gou, Kun, Liu, Xiaocong, Zhou, Yue, Zou, Jiao, Chen, Qiang, Luo, Youfu, Zhao, Yinglan

“…Dihydroorotate dehydrogenase (DHODH) is a quite attractive target in cancer therapy. Nevertheless, the antitumor effects of DHODH inhibitors against colorectal…”
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Pharmacological inhibition of LSD1 suppresses growth of hepatocellular carcinoma by inducing GADD45B by Sang, Na, Zhong, Xi, Gou, Kun, Liu, Huan, Xu, Jing, Zhou, Yang, Zhou, Xia, Liu, Yuanzhi, Chen, Zhiqian, Zhou, Yue, Li, Yan, Tao, Lei, Su, Na, Zhou, Lingyun, Qiu, Jiahao, Yang, Xinyu, Zuo, Zeping, Fu, Li, Zhang, Jingyao, Li, Dan, Li, Cong, Sun, Qingxiang, Lei, Jian, Li, Rui, Yang, Shengyong, Cen, Xiaobo, Zhao, Yinglan

“…Lysine‐specific histone demethylase 1 (LSD1) is an attractive target for malignancies therapy. Nevertheless, its role in hepatocellular carcinoma (HCC)…”
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Computational modeling of circular crack-tip fields under tensile loading in a strain-limiting elastic solid by Gou, Kun, Mallikarjunaiah, S.M.

“…Recent interest in developing new constitutive models for the behavior of elastic materials has led to a new nonlinear theory of elasticity, wherein the…”
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Finite element study of V-shaped crack-tip fields in a three-dimensional nonlinear strain-limiting elastic body by Gou, Kun, Mallikarjunaiah, S. M.

“…We study the crack-tip fields in a three-dimensional (3D) plate with a V-shaped crack employing Rajagopal’s theory of elasticity with the strain-limiting…”
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Finite element study of V-shaped crack-tip fields in a three-dimensional nonlinear strain-limiting elastic body by Gou, Kun, Mallikarjunaiah, S. M.

“…We study the crack-tip fields in a three-dimensional (3D) plate with a V-shaped crack employing Rajagopal’s theory of elasticity with the strain-limiting…”
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A Study on Estimating the Parameter of the Truncated Geometric Distribution by Park, Chanseok, Gou, Kun, Wang, Min

“…We consider the truncated geometric distribution and analyze the condition under which a nontrivial maximum likelihood (ML) estimator of the parameter p…”
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Generation, Transmission, and Regulation of Mechanical Forces in Embryonic Morphogenesis by Sutlive, Joseph, Xiu, Haning, Chen, Yunfeng, Gou, Kun, Xiong, Fengzhu, Guo, Ming, Chen, Zi

“…Embryonic morphogenesis is a biological process which depicts shape forming of tissues and organs during development. Unveiling the roles of mechanical forces…”
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Mechanical characterization of human umbilical arteries by thick-walled models: Enhanced vascular compliance by removing an abluminal lining by Gou, Kun, Hu, Jin-Jia, Baek, Seungik

“…The decellularized human umbilical artery (HUA) is considered as a promising option for small-diameter, tissue-engineered vascular grafts (TEVGs). Our previous…”
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Stress-Swelling Finite Element Modeling of Cervical Response With Homeostatic Collagen Fiber Distributions by Gou, Kun, Topol, Heiko, Demirkoparan, Hasan, Pence, Thomas J

“…During pregnancy, the cervix experiences significant mechanical property change due to tissue swelling, and to ongoing changes in the collagen content. In this…”
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Finite element simulation of intimal thickening in 2D multi-layered arterial cross sections by morphoelasticity by Fok, Pak-Wing, Gou, Kun

“…Morphoelasticity is a framework commonly employed to describe tissue growth. Its central premise is the decomposition of the deformation gradient into the…”
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On compressible versions of the incompressible neo-Hookean material by Pence, Thomas J, Gou, Kun

“…We consider three different compressible versions of the conventional incompressible neo-Hookean material model. The different versions are not new and have…”
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