Search Results - "Gou, Deming"

Enhancing RNA-seq bias mitigation with the Gaussian self-benchmarking framework: towards unbiased sequencing data by Su, Qiang, Long, Yi, Gou, Deming, Quan, Junmin, Lian, Qizhou

“…RNA sequencing is a vital technique for analyzing RNA behavior in cells, but it often suffers from various biases that distort the data. Traditional methods to…”
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Elevated plasma miR-133b and miR-221-3p as biomarkers for early Parkinson’s disease by Chen, Qihua, Deng, Na, Lu, Ke, Liao, Qiao, Long, Xiaoyan, Gou, Deming, Bi, Fangfang, Zhou, Jinxia

“…Blood circulating microRNAs (miRNAs) are proposed to be promising biomarkers for many neurodegenerative disorders, including Parkinson’s disease (PD). However,…”
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MiR-103 controls milk fat accumulation in goat (Capra hircus) mammary gland during lactation by Lin, Xianzi, Luo, Jun, Zhang, Liping, Wang, Wei, Gou, Deming

“…Milk is the primary source of nutrition for young mammals including humans. The nutritional value of milk is mainly attributable to fats and proteins…”
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Surface Plasmon-Assisted Fluorescence Enhancing and Quenching: From Theory to Application by Su, Qiang, Jiang, Cheng, Gou, Deming, Long, Yi

“…The integration of surface plasmon resonance and fluorescence yields a multiaspect improvement in surface fluorescence sensing and imaging, leading to a…”
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Anthocyanin-rich fractions from red raspberries attenuate inflammation in both RAW264.7 macrophages and a mouse model of colitis by Li, Li, Wang, Liyan, Wu, Zhiqin, Yao, Lijun, Wu, Yonghou, Huang, Lian, Liu, Kan, Zhou, Xiang, Gou, Deming

“…Edible berries have a broad spectrum of biomedical functions, including improving immune responses and reducing risk for chronic diseases. In this study, the…”
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MicroRNA-21 plays a role in hypoxia-mediated pulmonary artery smooth muscle cell proliferation and migration by Sarkar, Joy, Gou, Deming, Turaka, Prasanna, Viktorova, Ekaterina, Ramchandran, Ramaswamy, Raj, J Usha

“…Hypoxia stimulates pulmonary artery smooth muscle cell (PASMC) proliferation. Recent studies have implicated an important role for microRNAs (miRNAs) in…”
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MSCs Therapy Reverse the Gut Microbiota in Hypoxia-Induced Pulmonary Hypertension Mice by Luo, Lingjie, Chen, Qinhua, Yang, Lei, Zhang, Zhenxia, Xu, Jihong, Gou, Deming

“…Mesenchymal stem cell (MSC) therapy is a promising therapeutic approach based on its strong effect on pulmonary hypertension (PH) in rats. However, the…”
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The Long Noncoding RNA LnRPT Is Regulated by PDGF-BB and Modulates the Proliferation of Pulmonary Artery Smooth Muscle Cells by Chen, Jidong, Guo, Jiao, Cui, Xiaolei, Dai, Yan, Tang, Zhixiong, Qu, Junle, Raj, J Usha, Hu, Qinghua, Gou, Deming

“…Pulmonary artery hypertension (PAH) is a rare and fatal disorder that involves extensive remodeling of the pulmonary arteries mediated by hyperproliferation of…”
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MiR-125a-5p ameliorates monocrotaline-induced pulmonary arterial hypertension by targeting the TGF-β1 and IL-6/STAT3 signaling pathways by Cai, Zongye, Li, Jian, Zhuang, Qi, Zhang, Xueming, Yuan, Ancai, Shen, Lan, Kang, Kang, Qu, Bo, Tang, Yuanjia, Pu, Jun, Gou, Deming, Shen, Jieyan

“…Pulmonary vascular remodeling due to excessive proliferation and resistance to apoptosis of pulmonary artery smooth muscle cells (PASMCs) is the hallmark…”
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Identification of reference genes for circulating microRNA analysis in colorectal cancer by Niu, Yanqin, Wu, Yike, Huang, Jinyong, Li, Qing, Kang, Kang, Qu, Junle, Li, Furong, Gou, Deming

“…Quantitative real-time PCR (qPCR) is the most frequently used method for measuring expression levels of microRNAs (miRNAs), which is based on normalization to…”
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Gut Microbiota and Metabolome Changes in Three Pulmonary Hypertension Rat Models by Luo, Lingjie, Yin, Haoyang, Gou, Deming

“…Dysbiosis of the gut microbiota and metabolites is found in both pulmonary hypertension patients and pulmonary hypertension rodent models. However, the exact…”
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Identification of microRNA-Like RNAs in the filamentous fungus Trichoderma reesei by solexa sequencing by Kang, Kang, Zhong, Jiasheng, Jiang, Liang, Liu, Gang, Gou, Christine Yuan, Wu, Qiong, Wang, You, Luo, Jun, Gou, Deming

“…microRNAs (miRNAs) are non-coding small RNAs (sRNAs) capable of negatively regulating gene expression. Recently, microRNA-like small RNAs (milRNAs) were…”
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miR-210 has an antiapoptotic effect in pulmonary artery smooth muscle cells during hypoxia by Gou, Deming, Ramchandran, Ramaswamy, Peng, Xiao, Yao, Lijun, Kang, Kang, Sarkar, Joy, Wang, Zhixin, Zhou, Guofei, Zhou, Goufei, Raj, J Usha

“…MicroRNAs (miRNAs) were recently reported to play an important role in the pathogenesis of pulmonary arterial hypertension (PAH), but it is not clear which…”
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Identification of circulating miRNA biomarkers based on global quantitative real-time PCR profiling by Kang, Kang, Peng, Xiao, Luo, Jun, Gou, Deming

“…MicroRNAs （miRNAs） are small noncoding RNAs （18-25 nucleotides） that regulate gene expression at the posttranscriptional level. Recent studies have…”
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Terminal modifications independent cell-free RNA sequencing enables sensitive early cancer detection and classification by Wang, Jun, Huang, Jinyong, Hu, Yunlong, Guo, Qianwen, Zhang, Shasha, Tian, Jinglin, Niu, Yanqin, Ji, Ling, Xu, Yuzhong, Tang, Peijun, He, Yaqin, Wang, Yuna, Zhang, Shuya, Yang, Hao, Kang, Kang, Chen, Xinchun, Li, Xinying, Yang, Ming, Gou, Deming

“…Cell-free RNAs (cfRNAs) offer an opportunity to detect diseases from a transcriptomic perspective, however, existing techniques have fallen short in generating…”
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mTOR/HDAC1 Crosstalk Mediated Suppression of ADH1A and ALDH2 Links Alcohol Metabolism to Hepatocellular Carcinoma Onset and Progression in silico by Zahid, Kashif Rafiq, Yao, Shun, Khan, Abdur Rehman Raza, Raza, Umar, Gou, Deming

“…Hepatocellular carcinoma (HCC) is ranked the third deadliest cancer worldwide whose molecular pathogenesis is not fully understood. Although deregulated…”
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A novel real-time PCR assay of microRNAs using S-Poly(T), a specific oligo(dT) reverse transcription primer with excellent sensitivity and specificity by Kang, Kang, Zhang, Xiaoying, Liu, Hongtao, Wang, Zhiwei, Zhong, Jiasheng, Huang, Zhenting, Peng, Xiao, Zeng, Yan, Wang, Yuna, Yang, Yi, Luo, Jun, Gou, Deming

“…MicroRNAs (miRNAs) are small, non-coding RNAs capable of postranscriptionally regulating gene expression. Accurate expression profiling is crucial for…”
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miR‐34b Modulates Skeletal Muscle Cell Proliferation and Differentiation by Tang, Zhixiong, Qiu, Huiling, Luo, Lan, Liu, Nian, Zhong, Jiasheng, Kang, Kang, Gou, Deming

“…ABSTRACT Myogenesis involves myoblast proliferation and differentiation to myocytes, followed by fusion and hypertrophy to form myotubes during muscle…”
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Loss of microRNA-17∼92 in smooth muscle cells attenuates experimental pulmonary hypertension via induction of PDZ and LIM domain 5 by Chen, Tianji, Zhou, Guofei, Zhou, Qiyuan, Tang, Haiyang, Ibe, Joyce Christina F, Cheng, Hongqiang, Gou, Deming, Chen, Ju, Yuan, Jason X-J, Raj, J Usha

“…Recent studies suggest that microRNAs (miRNAs) play important roles in regulation of pulmonary artery smooth muscle cell (PASMC) phenotype and are implicated…”
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MicroRNAs in Pulmonary Hypertension, from Pathogenesis to Diagnosis and Treatment by Xu, Junhua, Linneman, John, Zhong, Yanfeng, Yin, Haoyang, Xia, Qinyi, Kang, Kang, Gou, Deming

“…Pulmonary hypertension (PH) is a fatal and untreatable disease, ultimately leading to right heart failure and eventually death. microRNAs are small, non-coding…”
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