Search Results - "Gotzsche, P C"

Overestimated lead times in cancer screening has led to substantial underestimation of overdiagnosis by Zahl, P-H, Jørgensen, K J, Gøtzsche, P C

“…Background: Published lead time estimates in breast cancer screening vary from 1 to 7 years and the percentages of overdiagnosis vary from 0 to 75%. The…”
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Commentary: Screening: a seductive paradigm that has generally failed us by Gotzsche, P.

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Niels Finsen's treatment for lupus vulgaris by Gøtzsche, PC

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Long-term harms from previous use of selective serotonin reuptake inhibitors: A systematic review by Danborg, P B, Valdersdorf, M, Gøtzsche, P C

“…Millions of people are treated with antidepressants like selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors…”
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Benefits and harms of antipsychotic drugs in drug-naïve patients with psychosis: A systematic review by Danborg, P B, Gøtzsche, P C

“…To study the benefits and harms of antipsychotics in drug-naïve patients with psychosis. This study is a systematic review and meta-analysis of…”
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Is the Placebo Powerless?: An Analysis of Clinical Trials Comparing Placebo with No Treatment by Hróbjartsson, Asbjørn, Gøtzsche, Peter C

“…Placebos have been reported to improve subjective and objective outcomes in up to 30 to 40 percent of patients with a wide range of clinical conditions, such…”
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Quality of Cochrane reviews: assessment of sample from 1998 by Olsen, Ole, Middleton, Philippa, Ezzo, Jeanette, Gøtzsche, Peter C, Hadhazy, Victoria, Herxheimer, Andrew, Kleijnen, Jos, McIntosh, Heather

“…Abstract Objective: To assess the quality of Cochrane reviews. Design: Ten methodologists affiliated with the Cochrane Collaboration independently examined, in…”
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House dust mite control measures in the management of asthma: meta-analysis by Gøtzsche, Peter C, Hammarquist, Cecilia, Burr, Michael

“…Abstract Objective To determine whether patients with asthma who are sensitive to mites benefit from measures designed to reduce their exposure to house dust…”
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Screening for breast cancer with mammography by Gøtzsche, P C, Nielsen, M

“…A variety of estimates of the benefits and harms of mammographic screening for breast cancer have been published and national policies vary. To assess the…”
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Informed choice requires information about both benefits and harms by Jørgensen, K J, Brodersen, J, Hartling, O J, Nielsen, M, Gøtzsche, P C

“…A study found that women participating in mammography screening were content with the programme and the paternalistic invitations that directly encourage…”
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SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials by Chan, An-Wen, Tetzlaff, Jennifer M, Gøtzsche, Peter C, Altman, Douglas G, Mann, Howard, Berlin, Jesse A, Dickersin, Kay, Hróbjartsson, Asbjørn, Schulz, Kenneth F, Parulekar, Wendy R, Krleža-Jerić, Karmela, Laupacis, Andreas, Moher, David

“…High quality protocols facilitate proper conduct, reporting, and external review of clinical trials. However, the completeness of trial protocols is often…”
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Polyclonal Immunoglobulin for Treatment of Bacterial Sepsis: A Systematic Review by Pildal, Julie, Gøtzsche, Peter C.

“…Randomized trials of adjunctive treatment of bacterial sepsis with polyclonal immunoglobulin show conflicting results. We performed a systematic review and a…”
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Estimation of lead time and overdiagnosis in breast cancer screening by Gøtzsche, P C, Jørgensen, K J, Mæhlen, J, Zahl, P-H

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General health checks in adults for reducing morbidity and mortality from disease: Cochrane systematic review and meta-analysis by Krogsbøll, Lasse T, Jørgensen, Karsten Juhl, Larsen, Christian Grønhøj, Gøtzsche, Peter C

“…Objectives To quantify the benefits and harms of general health checks in adults with an emphasis on patient-relevant outcomes such as morbidity and mortality…”
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Meta-analysis of short term low dose prednisolone versus placebo and non-steroidal anti-inflammatory drugs in rheumatoid arthritis by Gøtzsche, Peter C, Johansen, Helle Krogh

“…Abstract Objective: To determine whether short term, oral low dose prednisolone (⩽15 mg daily) is superior to placebo and non-steroidal anti-inflammatory drugs…”
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Definition, reporting, and interpretation of composite outcomes in clinical trials: systematic review by Cordoba, Gloria, Schwartz, Lisa, Woloshin, Steven, Bae, Harold, Gøtzsche, Peter C

“…Objective To study how composite outcomes, which have combined several components into a single measure, are defined, reported, and interpreted.Design…”
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Meta-analysis of prophylactic or empirical antifungal treatment versus placebo or no treatment in patients with cancer complicated by neutropenia by Gøtzsche, Peter C, Johansen, Helle Krogh

“…Abstract Objective:To determine whether antifungal agents given prophylactically or empirically decrease morbidity and mortality in patients with cancer…”
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Author’s reply on: ‘House dust mite control measures for asthma by Gøtzsche, P. C., Johansen, H. K.

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Meta-analysis of resting metabolic rate in formerly obese subjects by Astrup, A, Gotzsche, P.C, Werken, K. van de, Ranneries, C, Toubro, S, Raben, A, Buemann, B

“…Background: A low resting metabolic rate (RMR) for a given body size and composition is partly genetically determined and has been suggested to be a risk…”
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House dust mite control measures for asthma by Gøtzsche, P C, Johansen, H K

“…This 2011 review predates current reporting standards and methodological expectations for Cochrane Reviews. It should not be used for clinical decision‐making…”
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