Search Results - "Gottstein, Jeanne"
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Pentoxifylline for the treatment of non-alcoholic steatohepatitis: a randomized controlled trial
Published in Annals of hepatology (01-07-2011)“…The burden of non-alcoholic steatohepatitis (NASH) is growing and current pharmacologic treatments are limited by side effects and inconsistent efficacy. Pilot…”
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The Role of Etiology in the Hyperamylasemia of Acute Liver Failure
Published in The American journal of gastroenterology (01-03-2009)“…Hyperamylasemia (HA) is often reported in patients with acute liver failure (ALF). Direct toxic effects of acetaminophen on the pancreas have been postulated,…”
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Mild hypothermia modifies ammonia-induced brain edema in rats after portacaval anastomosis
Published in Gastroenterology (New York, N.Y. 1943) (01-03-1999)“…Background & Aims: The pathogenesis of brain edema in fulminant hepatic failure is still unresolved. Mild hypothermia (33°–35°C) can ameliorate brain edema…”
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Chronic hyponatremia exacerbates ammonia-induced brain edema in rats after portacaval anastomosis
Published in Journal of hepatology (01-10-1998)“…Background/Aim: Abnormalities in brain organic osmolytes are associated with hepatic encephalopathy and with chronic hyponatremia. In spite of the high…”
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Impact of preoperative overt hepatic encephalopathy on neurocognitive function after liver transplantation
Published in Liver transplantation (01-02-2009)“…In the current Model for End‐Stage Liver Disease allocation system, patients are at risk of suffering repeated episodes of hepatic encephalopathy (HE) while…”
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Dysregulation of the unfolded protein response in db/db mice with diet‐induced steatohepatitis
Published in Hepatology (Baltimore, Md.) (01-11-2011)“…In humans with nonalcoholic fatty liver, diabetes is associated with more advanced disease. We have previously shown that diabetic db/db mice are highly…”
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Screening for Wilson disease in acute liver failure: A comparison of currently available diagnostic tests
Published in Hepatology (Baltimore, Md.) (01-10-2008)“…Acute liver failure (ALF) due to Wilson disease (WD) is invariably fatal without emergency liver transplantation. Therefore, rapid diagnosis of WD should aid…”
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Cerebral blood flow and the development of ammonia‐induced brain edema in rats after portacaval anastomosis
Published in Hepatology (Baltimore, Md.) (01-10-1999)“…Two mechanisms may account for brain edema in fulminant hepatic failure: the osmotic effects of brain glutamine, a product of ammonia detoxification, and a…”
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Elevated troponin I levels in acute liver failure: Is myocardial injury an integral part of acute liver failure?
Published in Hepatology (Baltimore, Md.) (01-06-2007)“…Although rare instances of cardiac injury or arrhythmias have been reported in acute liver failure (ALF), overall, the heart is considered to be spared in this…”
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The Role of Etiology in the Hyperamylasemia of Acute Liver Failure
Published in The American journal of gastroenterology (01-03-2009)Get full text
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Cerebral hyperemia and nitric oxide synthase in rats with ammonia-induced brain edema
Published in Journal of hepatology (01-04-2001)“…Background/Aim : Brain edema is a common fatal complication in acute liver failure. It is related to an acute change in brain osmolarity secondary to the glial…”
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Indomethacin prevents the development of experimental ammonia-induced brain edema in rats after portacaval anastomosis
Published in Hepatology (Baltimore, Md.) (01-08-2001)“…Patients with fulminant hepatic failure (FHF) die with brain edema, exhibiting an increased cerebral blood flow (CBF) at the time of cerebral swelling. Mild…”
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Predictive value of actin‐free Gc‐globulin in acute liver failure
Published in Liver transplantation (01-09-2007)“…Serum concentrations of the actin scavenger Gc‐globulin may provide prognostic information in acute liver failure (ALF). The fraction of Gc‐globulin not bound…”
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Pentoxifylline for the treatment of non-alcoholic steatohepatitis: a randomized controlled trial(†)(†)This trial is posted on clinicaltrials.gov (NCT00267670). This research was supported by investigator initiated funds
Published in Annals of hepatology (01-07-2011)“…Introduction. The burden of non-alcoholic steatohepatitis (NASH) is growing and current pharmacologic treatments are limited by side effects and inconsistent…”
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Role of the liver in the disposition of intravenous nitroglycerin in the rat
Published in Biochemical pharmacology (15-08-1984)“…Previous studies have indicated that the liver is the main site of nitroglycerin (NTG) elimination when the drug is systematically infused. To examine this…”
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Vasopressin accelerates experimental ammonia-induced brain edema in rats after portacaval anastomosis
Published in Journal of hepatology (01-08-2003)“…Background/Aims: Cerebral hyperemia is an important contributor to the development of brain edema in fulminant hepatic failure. Rats receiving an ammonia…”
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CEREBRAL HYPEREMIA AND BRAIN EDEMA IN EXPERIMENTAL ACUTE LIVER FAILURE (ALF)
Published in Transplantation (01-10-1998)Get full text
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