Search Results - "Gottschall, P.E"
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Lectican proteoglycans, their cleaving metalloproteinases, and plasticity in the central nervous system extracellular microenvironment
Published in Neuroscience (16-08-2012)“…Highlights ► Chondroitin sulfate proteoglycans in the brain matrix regulate neural plasticity. ► Extracellular metalloproteinases alter structural and synaptic…”
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Association between protease-specific proteolytic cleavage of brevican and synaptic loss in the dentate gyrus of kainate-treated rats
Published in Neuroscience (01-11-2002)“…Proteolytic fragments generated by ADAMTS ( a d isintegrin a nd m etalloprotease with t hrombo s pondin motifs)-mediated cleavage of the aggregating…”
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Inhibition of gelatinase activity reduces neural injury in an ex vivo model of hypoxia–ischemia
Published in Neuroscience (02-06-2009)“…Abstract Perinatal hypoxia–ischemia (H-I) often manifests as cognitive and/or motor disturbances that appear early in development. Growing evidence indicates…”
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Adeno-Associated Viral Vector Mediated Gene Delivery of Endothelin Converting Enzyme Reduces Aβ Deposits in APP+PS-1 Transgenic Mice
Published in Molecular therapy (29-07-2008)“…Reduction of Aβ deposition is a major therapeutic strategy in Alzheimer's disease (AD). The concentration of Aβ in the brain is modulated, not only by Aβ…”
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Low doses of deglycosylated anti-Aβ antibodies reduce amyloid pathology and reverse cognitive deficits in old app transgenic mice
Published in Experimental neurology (01-04-2006)Get full text
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Bromocryptine prevents the decline in tuberoinfundibular neuronal release of dopamine after removal of chronic estrogen treatment
Published in Proceedings of the Society for Experimental Biology and Medicine (01-11-1987)“…Prolonged exposure to estradiol 17-beta (E2) in rats has been shown to decrease dopamine (DA) synthesis in and release from tuberoinfundibular dopaminergic…”
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Uptake and release of [3H]dopamine by the median eminence: evidence for presynaptic dopaminergic receptors and for dopaminergic feedback inhibition
Published in Neuroscience (01-11-1983)“…The accumulation and release of [3H]dopamine by the median eminence in vitro was studied after treatments with different pharmacological agents, to determine…”
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