Search Results - "Gottschalk, A"
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Anxiety, depression and quality of life in family caregivers of palliative cancer patients during home care and after the patient's death
Published in European journal of cancer care (01-03-2018)“…We examined psychological parameters in family caregivers of palliative cancer patients before and after the death of the patients. Caregivers’ data about…”
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Anti-Inflammatory Chromatinscape Suggests Alternative Mechanisms of Glucocorticoid Receptor Action
Published in Immunity (Cambridge, Mass.) (15-08-2017)“…Despite the widespread use of glucocorticoids (GCs), their anti-inflammatory effects are not understood mechanistically. Numerous investigations have examined…”
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TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo
Published in The Journal of experimental medicine (02-08-2010)“…T cell receptor (TCR) ligation is required for the extrathymic differentiation of forkhead box p3(+) (Foxp3(+)) regulatory T cells. Several lines of evidence…”
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Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88
Published in Scientific reports (03-05-2017)“…TLR4 signalling through the MyD88 and TRIF-dependent pathways initiates translocation of the transcription factor NF-κB into the nucleus. In cell population…”
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Visualization of electrolyte filling process and influence of vacuum during filling for hard case prismatic lithium ion cells by neutron imaging to optimize the production process
Published in Journal of power sources (15-03-2018)“…The process of filling electrolyte into lithium ion cells is time consuming and critical to the overall battery quality. However, this process is not well…”
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Pathogenic Inflammation and Its Therapeutic Targeting in Systemic Lupus Erythematosus
Published in Frontiers in immunology (28-10-2015)“…Systemic lupus erythematosus (SLE, lupus) is a highly complex and heterogeneous autoimmune disease that most often afflicts women in their child-bearing years…”
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The Role of Innate Lymphoid Cells in Chronic Respiratory Diseases
Published in Frontiers in immunology (22-09-2021)“…The lung is a vital mucosal organ that is constantly exposed to the external environment, and as such, its defenses are continuously under threat. The…”
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Arterial pressure above the upper cerebral autoregulation limit during cardiopulmonary bypass is associated with postoperative delirium
Published in British journal of anaesthesia : BJA (01-12-2014)“…Mean arterial pressure (MAP) below the lower limit of cerebral autoregulation during cardiopulmonary bypass (CPB) is associated with complications after…”
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The dualistic role of Lyn tyrosine kinase in immune cell signaling: implications for systemic lupus erythematosus
Published in Frontiers in immunology (28-06-2024)“…Systemic lupus erythematosus (SLE, lupus) is a debilitating, multisystem autoimmune disease that can affect any organ in the body. The disease is characterized…”
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Evidence of an association between brain cellular injury and cognitive decline after non-cardiac surgery
Published in British journal of anaesthesia : BJA (01-01-2016)“…Postoperative cognitive dysfunction (POCD) is common after non-cardiac surgery, but the mechanism is unclear. We hypothesized that decrements in cognition 1…”
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Time spent in face-to-face patient care and work outside the examination room
Published in Annals of family medicine (01-11-2005)“…Contrary to physicians' concerns that face-to-face patient time is decreasing, data from the National Ambulatory Medical Care Survey (NAMCS) indicate that…”
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Attenuated T cell responses to a high-potency ligand in vivo
Published in PLoS biology (01-09-2010)“…αβ T cell receptor (TCR) recognition of foreign peptides bound to major histocompatibility complex (pMHC) molecules on the surface of antigen presenting cells…”
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Identification of Cell Surface Molecules That Determine the Macrophage Activation Threshold Associated With an Early Stage of Malignant Transformation
Published in Frontiers in immunology (12-10-2021)“…The ability of immune cells to sense changes associated with malignant transformation as early as possible is likely to be important for the successful outcome…”
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Consensus statement from the BJA Workshop on Cancer and Anaesthesia
Published in British journal of anaesthesia (01-01-2015)Get full text
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Loss of CD11b Accelerates Lupus Nephritis in Lyn-Deficient Mice Without Disrupting Glomerular Leukocyte Trafficking
Published in Frontiers in immunology (12-05-2022)“…Systemic lupus erythematosus (SLE) is a complex, heterogeneous autoimmune disease. A common manifestation, lupus nephritis, arises from immune complex…”
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Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses
Published in Proceedings of the National Academy of Sciences - PNAS (17-01-2012)“…The strength of T-cell receptor (TCR) stimulation and subsequent T-cell response depend on a combination of peptide-major histocompatibility complex (pMHC)…”
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Tunnelling of thoracic epidural catheters is associated with fewer catheter-related infections: a retrospective registry analysis
Published in British journal of anaesthesia : BJA (01-04-2016)“…Catheter-related infections are a serious complication of continuous thoracic epidural analgesia. Tunnelling catheters subcutaneously may reduce infection…”
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Preventing and treating pain after thoracic surgery
Published in Anesthesiology (Philadelphia) (01-03-2006)Get full text
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Synthetic retinal analogues modify the spectral and kinetic characteristics of microbial rhodopsin optogenetic tools
Published in Nature communications (15-12-2014)“…Optogenetic tools have become indispensable in neuroscience to stimulate or inhibit excitable cells by light. Channelrhodopsin-2 (ChR2) variants have been…”
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Evaluation of ultrasound-based prostate localization for image-guided radiotherapy
Published in International journal of radiation oncology, biology, physics (01-11-2003)“…To evaluate the use of the ultrasound-based BAT system for daily prostate alignment. Prostate alignments using the BAT system were compared with alignments…”
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