Search Results - "Gottier, C"

PTPN2 controls differentiation of CD4+ T cells and limits intestinal inflammation and intestinal dysbiosis by Spalinger, M R, Kasper, S, Chassard, C, Raselli, T, Frey-Wagner, I, Gottier, C, Lang, S, Atrott, K, Vavricka, S R, Mair, F, Becher, B, Lacroix, C, Fried, M, Rogler, G, Scharl, M

“…Loss-of-function variants within the gene locus encoding protein tyrosine phosphatase non-receptor type 2 (PTPN2) are associated with increased risk for…”
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DOP51 Loss of PTPN23 in the intestinal epithelium results in epithelial hyperproliferation and lethal diarrhea in a microbiota dependent manner by Spalinger, M, Sanchez Alvarez, R, Gottier, C, Montalban-Arques, A, Schwarzfischer, M, Niechcial, A, Scharl, M

“…Abstract Background Protein tyrosine phosphtase non-receptor type 23 (PTPN23) plays a critical role in regulating epidermal growth factor (EGF) receptor…”
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P006 Loss of protein tyrosine phosphatase non-receptor type 23 (PTPN23) in intestinal epithelial cells induces inflammation and epithelial hyperproliferation by Montalban-Arques, A, Gottier, C, Olivares-Rivas, I, Scharl, M, Spalinger, M

“…Abstract Background Colorectal carcinoma (CRC) is still a mayor complication in patients with inflammatory bowel disease (IBD) with colonic involvement…”
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P068 Loss of PTPN22 abrogates the beneficial effect of faecal microbiota transfer by Spalinger, M, Schwarzfischer, M, Gottier, C, Hering, L, Lang, S, Rogler, G, Scharl, M

“…Abstract Background In inflammatory bowel disease (IBD), shifts in microbiota composition and reduced microbial diversity have been described. There are…”
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OP030 Loss of PTPN2 in dendritic cells promotes T-cell activation and expression of co-stimulatory molecules by Hering, L, Gottier, C, Lang, S, Becher, B, Rogler, G, Scharl, M, Spalinger, M

“…Abstract Background Variants within the gene locus encoding protein tyrosine phosphatase non-receptor type 2 (PTPN2) are associated with the development of…”
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DOP02 Supplementation with butyrate producing bacteria reduces tumour load in a mouse model of colitis-associated cancer by Montalban Arques, A, Olivares Rivas, I, Atrott, K, Gottier, C, Lang, S, Leventhal, G, DeWouters, T, Scharl, M, Spalinger, M

“…Abstract Background Colorectal carcinoma is still a severe complication in patients with long-standing and severe ulcerative colitis. Current guidelines…”
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P768 Co-housing DSS treated mice with healthy mice results in faster recovery and normalization of the intestinal microbiota by Spalinger, M., Gottier, C., Hering, L., Lang, S., Rogler, G., Scharl, M.

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DOP013 An IBD-associated variant in PTPN2 promotes inflammatory responses but enhances the anti-inflammatory effect of spermidine by Butter, M, Obialo, N, Bäbler, K, Van der Lely, L, Lang, S, Gottier, C, Scharl, M, Spalinger, M R

“…Abstract Background The single-nucleotoide polymorphisms (SNP) rs1893217, located in the gene locus encoding protein tyrosine phosphatase non-receptor type 2…”
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P046 Presence of an autoimmunity-associated variant in PTPN22 promotes chronic colitis in a microbiota dependent manner by Spalinger, M, Schwarzfischer, M, Hering, L, Geirnaert, A, Gottier, C, Lang, S, Lacroix, C, Rogler, G, Scharl, M

“…Abstract Background The gut microbiota is an important factor for intestinal health, and intestinal inflammation is accompanied with profound changes in…”
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DOP34 Transplantation of human intestine into the mouse: A novel platform for study of inflammatory enterocutaneous fistulas by Bruckner, R S, Nissim-Eliraz, E, Marsiano, N, Nir, E, Shemesh, H, Leutenegger, M, Gottier, C, Lang, S, Spalinger, M R, Leibl, S, Rogler, G, Yagel, S, Scharl, M, Shpigel, N Y

“…Abstract Background In Crohn’s disease patients, enteric and perianal fistulas represent a severe and medically challenging comorbidity that affects a broad…”
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P034 Validation of a novel xenograft mouse model for intestinal fistulas by Bruckner, R S, Marsiano, N, Nissim-Eliraz, E, Nir, E, Leutenegger, M, Gottier, C, Lang, S, Spalinger, M, Rogler, G, Yagel, S, Scharl, M, Shpigel, N Y

“…Abstract Background Fistulas are a frequent, relapsing complication in Crohn’s disease (CD), affecting up to 50% of patients. Surgical resection is regularly…”
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DOP089 PTPN2 controls intestinal inflammation and promotes colitis-associated tumour formation via control of inflammasome activation and IL-1alpha release by Spalinger, M., Hering, L., Manzini, R., Riggs, J.B., Gottier, C., Atrott, K., Fettelschoss, A., Kündig, T., Fried, M., Rogler, G., Scharl, M.

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