Search Results - "Gotschlich, Emil C."
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CGM1a Antigen of Neutrophils, a Receptor of Gonococcal Opacity Proteins
Published in Proceedings of the National Academy of Sciences - PNAS (10-12-1996)“…Neisseria gonorrhoeae (GC) or Escherichia coli expressing phase-variable opacity (Opa) protein (Opa+GC or Opa+GC or Opa+E. coli) adhere to human neutrophils…”
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ComE, a Competence Protein from Neisseria gonorrhoeae with DNA-Binding Activity
Published in Journal of Bacteriology (01-05-2001)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Meningococcal meningitis in sub-Saharan Africa: the case for mass and routine vaccination with available polysaccharide vaccines
Published in Bulletin of the World Health Organization (01-10-2003)“…Endemic and epidemic group A meningococcal meningitis remains a major cause of morbidity and mortality in sub-Saharan Africa, despite the availability of the…”
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A path to discovery: the career of Maclyn McCarty
Published in PLoS biology (01-10-2005)“…In parallel, McCarty studied patients with rheumatic fever admitted to the Rockefeller Hospital as well as valuable specimen collections from military…”
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Identification of the Gene (lgtG) Encoding the Lipooligosaccharide β Chain Synthesizing Glucosyl Transferase from Neisseria gonorrhoeae
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1998)“…The lipooligosaccharide from Neisseria gonorrhoeae (GC), consists of lipid A, an oligosaccharide core and three branches, α , β , and γ . We report the cloning…”
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The career of Maclyn McCarty
Published in The Journal of experimental medicine (06-06-2005)“…On January 2, 2005, the scientific community lost a valued colleague and friend. Maclyn McCarty, or "Mac," as he was better known, was perhaps most recognized…”
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Surveillance for Bacterial Meningitis by Means of Polymerase Chain Reaction
Published in Clinical infectious diseases (01-01-2005)“…Or, as the authors point out, considering the average life expectancy of a Burkinan, 1 in 50 persons will develop bacterial meningitis, ~30% of these persons…”
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Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection
Published in Proceedings of the National Academy of Sciences - PNAS (25-05-2010)“…Metabolic adaptation to the host niche is a defining feature of the pathogenicity of Mycobacterium tuberculosis (Mtb). In vitro, Mtb is able to grow on a…”
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Effect of α-oligosaccharide phenotype of Neisseria gonorrhoeae strain MS11 on invasion of chang conjunctival, HEC-1-B endometrial, and ME-180 cervical cells
Published in Infection and immunity (01-12-2000)“…The genes encoding the glycosyltransferases responsible for the addition of the five sugars in the alpha-oligosaccharide (alpha-OS) moiety of…”
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"Love's labours lost": failure to implement mass vaccination against group A meningococcal meningitis in sub-Saharan Africa
Published in The Lancet (British edition) (20-09-1997)Get more information
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Copper resistance is essential for virulence of Mycobacterium tuberculosis
Published in Proceedings of the National Academy of Sciences - PNAS (25-01-2011)“…Copper (Cu) is essential for many biological processes, but is toxic when present in excessive amounts. In this study, we provide evidence that Cu plays a…”
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LapD is a bis-(3',5')-cyclic dimeric GMP-binding protein that regulates surface attachment by Pseudomonas fluorescens Pf0-1
Published in Proceedings of the National Academy of Sciences - PNAS (03-03-2009)“…The second messenger cyclic dimeric GMP (c-di-GMP) regulates surface attachment and biofilm formation by many bacteria. For Pseudomonas fluorescens Pf0-1,…”
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Host cell-free growth of the Q fever bacterium Coxiella burnetii
Published in Proceedings of the National Academy of Sciences - PNAS (17-03-2009)“…The inability to propagate obligate intracellular pathogens under axenic (host cell-free) culture conditions imposes severe experimental constraints that have…”
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Broad spectrum O-linked protein glycosylation in the human pathogen Neisseria gonorrhoeae
Published in Proceedings of the National Academy of Sciences - PNAS (17-03-2009)“…Protein glycosylation is an important element of biologic systems because of its significant effects on protein properties and functions. Although prominent…”
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Generation of targeted Chlamydia trachomatis null mutants
Published in Proceedings of the National Academy of Sciences - PNAS (26-04-2011)“…Chlamydia trachomatis is an obligate intracellular bacterial pathogen that infects hundreds of millions of individuals globally, causing blinding trachoma and…”
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Effects of recA Mutations on Pilus Antigenic Variation and Phase Transitions in Neisseria gonorrhoeae
Published in Genetics (Austin) (01-11-1987)“…Intragenic recombination between the single complete pilin gene (expression locus) and multiple, distinct, partial pilin gene copies (silent, storage loci) is…”
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Structural studies on the sialic acid polysaccharide antigen of Escherichia coli strain Bos-12
Published in Biochemistry (Easton) (09-08-1977)“…A polysaccharide, antigenically related to group C meningococcus, has been isolated from Escherichia coli strain Bos-12 (016; K92; NM). Like groups B and C…”
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adhesion protein of Salmonella enterica serovar Typhi is required for pathogenesis and potential target for vaccine development
Published in Proceedings of the National Academy of Sciences - PNAS (22-02-2011)“…More than half of all Salmonella enterica serovar Typhi genes still remain unannotated. Although pathogenesis of S. Typhi is incompletely understood, treatment…”
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Discovery and Characterization of Sialic Acid O-Acetylation in Group B Streptococcus
Published in Proceedings of the National Academy of Sciences - PNAS (27-07-2004)“…Group B Streptococcus (GBS) is the leading cause of human neonatal sepsis and meningitis. The GBS capsular polysaccharide is a major virulence factor and the…”
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