Search Results - "Gotoh, Minoru"

ALLERGEN IMMUNOTHERAPY FOR ALLERGIC RHINITIS: TO INTRODUCE SUBCUTANEOUS IMMUNOTHERAPY by Gotoh, Minoru

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From the genesis to the present: The evolution of sublingual immunotherapy for cedar pollinosis by Gotoh, Minoru, Kaminuma, Osamu, Okubo, Kimihiro

“…In 2004, we started the initial attempt to evaluate the efficacy of SLIT for Japanese cedar pollinosis (JCP) using Japanese cedar (JC) pollen extract solution…”
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Treatment duration-dependent efficacy of Japanese cedar pollen sublingual immunotherapy: Evaluation of a phase II/III trial over three pollen dispersal seasons by Yonekura, Syuji, Gotoh, Minoru, Kaneko, Shinya, Kanazawa, Keishi, Takeuji, Yoshie, Okubo, Kimihiro, Okamoto, Yoshitaka

“…We conducted a randomized, placebo-controlled, double-blind clinical trial to investigate the optimal dose and long-term efficacy and safety of Japanese cedar…”
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Executive summary: Japanese guidelines for allergic rhinitis 2020 by Okano, Mitsuhiro, Fujieda, Shigeharu, Gotoh, Minoru, Kurono, Yuichi, Matsubara, Atsushi, Ohta, Nobuo, Kamijo, Atsushi, Yamada, Takechiyo, Nakamaru, Yuji, Asako, Mikiya, Sakurai, Daiju, Terada, Tetsuya, Yonekura, Shuji, Sakashita, Masafumi, Okubo, Kimihiro

“…The Practical Guideline for the Management of Allergic Rhinitis, the fist guideline for allergic rhinitis in Japan, was prepared after a symposium held by the…”
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Same dose of Japanese cedar pollen sublingual immunotherapy tablets is optimal for allergic rhinitis caused by either Japanese cedar or Japanese cypress pollen by Gotoh, Minoru, Kurokawa, Tomoya, Yonekura, Syuji, Okano, Mitsuhiro, Maekawa, Yuriko, Okamoto, Yoshitaka, Okubo, Kimihiro

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Japanese cedar pollen sublingual immunotherapy is effective in treating seasonal allergic rhinitis during the pollen dispersal period for Japanese cedar and Japanese cypress by Yonekura, Syuji, Gotoh, Minoru, Okano, Mitsuhiro, Kurokawa, Tomoya, Maekawa, Yuriko, Okubo, Kimihiro, Okamoto, Yoshitaka

“…Dear Editor, In Japan, allergic rhinitis is one of the most prevalent allergic diseases, and there has been an increase in seasonal allergic rhinitis in recent…”
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Disease-Modifying Effect of Japanese Cedar Pollen Sublingual Immunotherapy Tablets by Yonekura, Syuji, Gotoh, Minoru, Kaneko, Shinya, Maekawa, Yuriko, Okubo, Kimihiro, Okamoto, Yoshitaka

“…Japanese cedar (JC) pollinosis is a common allergic rhinitis in Japan. JC pollen sublingual immunotherapy (SLIT) tablets are licensed for the treatment of JC…”
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Re-evaluation of over-the-counter histamine H1-receptor antagonists based on their effects on murine models of allergen-induced nasal hyperresponsiveness by Uda, Naoto, Ogata, Sawako, Yamasaki, Norimasa, Miura, Shuka, Hosomi, Naohisa, Mori, Akio, Gotoh, Minoru, Miura, Kento, Kaminuma, Osamu

“…T cells play an essential role in the development of allergen-induced nasal hyperresponsiveness (NHR), a pathophysiological response in allergic rhinitis. The…”
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ALLERGIC RHINITIS : DIAGNOSIS AND TREATMENT BASED ON THE GUIDELINES by Gotoh, Minoru

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Long-Term Efficacy and Dose-Finding Trial of Japanese Cedar Pollen Sublingual Immunotherapy Tablet by Gotoh, Minoru, Yonekura, Syuji, Imai, Toru, Kaneko, Shinya, Horikawa, Eiji, Konno, Akiyoshi, Okamoto, Yoshitaka, Okubo, Kimihiro

“…Japanese cedar (JC) pollinosis is a common allergic rhinitis in Japan. The JC pollen sublingual immunotherapy (SLIT) tablet was developed using the highest…”
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Sublingual Immunotherapy: How Sublingual Allergen Administration Heals Allergic Diseases; Current Perspective about the Mode of Action by Gotoh, Minoru, Kaminuma, Osamu

“…Owing to the successful application of sublingual immunotherapy (SLIT), allergen immunotherapy (AIT) has become one of the leading treatments for allergic…”
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GUIDE TO ALLERGEN IMMUNOTHERAPY FOR MITE ALLERGY by Gotoh, Minoru

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Safety profile and immunological response of dual sublingual immunotherapy with house dust mite tablet and Japanese cedar pollen tablet by Gotoh, Minoru, Okubo, Kimihiro, Yuta, Atsushi, Ogawa, Yukiko, Nagakura, Hitoshi, Ueyama, Shigehiro, Ueyama, Tomoyo, Kawashima, Kayoko, Yamamoto, Masashi, Fujieda, Shigeharu, Sakashita, Masafumi, Sakamoto, Hirokazu, Iwasaki, Naruhito, Mori, Eri, Endo, Tomonori, Ohta, Nobuo, Kitazawa, Hiroshi, Okano, Mitsuhiro, Asako, Mikiya, Takada, Masami, Terada, Tetsuya, Inaka, Yuko, Yonekura, Syuji, Matsuoka, Tomokazu, Kaneko, Shinya, Hata, Hiroki, Hijikata, Nagisa, Tanaka, Hisataka, Masuyama, Keisuke, Okamoto, Yoshitaka

“…There have been no studies of dual administration of sublingual immunotherapy (SLIT) tablets for perennial and seasonal allergic rhinitis. This trial…”
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Identification of biomarker sets for predicting the efficacy of sublingual immunotherapy against pollen-induced allergic rhinitis by Gotoh, Minoru, Kaminuma, Osamu, Nakaya, Akihiro, Katayama, Kazufumi, Motoi, Yuji, Watanabe, Nobumasa, Saeki, Mayumi, Nishimura, Tomoe, Kitamura, Noriko, Yamaoka, Kazuko, Okubo, Kimihiro, Hiroi, Takachika

“…Sublingual immunotherapy (SLIT) is effective against allergic rhinitis, although a substantial proportion of individuals is refractory. Herein, we describe a…”
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An analysis of factors related to the effect of sublingual immunotherapy on Japanese cedar pollen induced allergic rhinitis by Yonekura, Syuji, Okamoto, Yoshitaka, Sakurai, Daiju, Okubo, Kimihiro, Gotoh, Minoru, Kaneko, Shinya, Konno, Akiyoshi

“…Sublingual immunotherapy (SLIT) can improve the symptoms of allergic rhinitis and modify its natural history; however, its efficacy varies among patients. This…”
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α7 nicotinic acetylcholine receptor agonist attenuates allergen-induced immediate nasal response in murine model of allergic rhinitis by YAMASHITA, Shuhei, MIURA, Kento, MATSUURA, Anna, YAMASAKI, Norimasa, UDA, Naoto, OGATA, Sawako, HOSOMI, Naohisa, NAKAJIMA, Shotaro, KITAMURA, Noriko, GOTOH, Minoru, MORI, Akio, KAMINUMA, Osamu

“…The expression of nicotinic acetylcholine receptor (nAChR) subunits on various immune cells suggests their involvement in allergic rhinitis. However, how…”
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SUBLINGUAL IMMUNOTHERAPY by Gotoh, Minoru

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Serum Cytokine Interactions Are Implicated in the Mechanism of Action of Sublingual Immunotherapy for Japanese Cedar Pollinosis by Shimada, Kenichi, Gotoh, Minoru, Okubo, Kimihiro, Hiroi, Takachika, Kaminuma, Osamu, Nakaya, Akihiro

“…Objective: This study aimed to investigate whether interactions between multiple serum cytokines may be implicated in the mechanism of action (MOA) of…”
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Microarray-Based Multivariate Analysis of the Effectiveness of Sublingual Immunotherapy for Cedar Pollinosis by Gotoh, Minoru, Kaminuma, Osamu, Hiroi, Takachika, Okubo, Kimihiro

“…Sublingual immunotherapy (SLIT) is an effective treatment for allergic diseases. However, the mechanism by which this therapy exhibits its efficacy has not…”
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Efficacy and safety of bilastine in Japanese patients with perennial allergic rhinitis: A multicenter, randomized, double-blind, placebo-controlled, parallel-group phase III study by Okubo, Kimihiro, Gotoh, Minoru, Asako, Mikiya, Nomura, Yasuyuki, Togawa, Michinori, Saito, Akihiro, Honda, Takayuki, Ohashi, Yoshihiro

“…Bilastine, a novel non-sedating second-generation H1 antihistamine, has been approved in most European countries since 2010. This study aimed to evaluate the…”
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