Search Results - "Goto, J"
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Activation of inositol 1,4,5-trisphosphate receptors during preconditioning low-frequency stimulation suppresses subsequent induction of long-term potentiation in hippocampal CA1 neurons
Published in Neuroscience (17-12-2015)“…Highlights • A train of LFS given prior to the delivery of HFS suppresses LTP induction in hippocampal CA1 neurons. • Co-activation of IP3 receptors and NMDA…”
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2
IFNβ-1b may severely exacerbate Japanese optic-spinal MS in neuromyelitis optica spectrum
Published in Neurology (19-10-2010)“…Interferon-β-1b (IFNβ-1b) has been used to prevent exacerbation of relapsing-remitting multiple sclerosis (RRMS) including optic-spinal multiple sclerosis…”
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Journal Article -
3
IFN beta -1b may severely exacerbate Japanese optic-spinal MS in neuromyelitis optica spectrum
Published in Neurology (19-10-2010)“…Background: Interferon- beta -1b (IFN beta -1b) has been used to prevent exacerbation of relapsing-remitting multiple sclerosis (RRMS) including optic-spinal…”
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4
Equilibrium Dynamics of β-N-Methylamino-L-Alanine (BMAA) and Its Carbamate Adducts at Physiological Conditions
Published in PloS one (11-08-2016)“…Elevated incidences of Amyotrophic Lateral Sclerosis/Parkinsonism Dementia complex (ALS/PDC) is associated with β-methylamino-L-alanine (BMAA), a non-protein…”
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5
Decreased Metallation and Activity in Subsets of Mutant Superoxide Dismutases Associated with Familial Amyotrophic Lateral Sclerosis
Published in The Journal of biological chemistry (03-05-2002)“…Over 90 different mutations in the gene encoding copper/zinc superoxide dismutase (SOD1) cause â¼2% of amyotrophic lateral sclerosis (ALS) cases by an unknown…”
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6
Therapeutic value of prenatal rapamycin treatment in a mouse brain model of tuberous sclerosis complex
Published in Human molecular genetics (01-12-2011)“…Epileptic seizures, particularly infantile spasms, are often seen in infants with tuberous sclerosis complex (TSC) soon after birth. It is feared that there…”
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7
Study of spatial resolution of proton computed tomography using a silicon strip detector
Published in Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment (2014)“…Proton computed tomography (CT) is an imaging technique using a high-energy proton beam penetrating the human body and shows promise for improving the quality…”
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8
Total deletion and a missense mutation of ITPR1 in Japanese SCA15 families
Published in Neurology (19-08-2008)“…Spinocerebellar ataxia type 15 (SCA15) is a progressive neurodegenerative disorder characterized by pure cerebellar ataxia, very slow progression, and distinct…”
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9
Machine Learning Approach for Gamma-ray Spectra Identification for Radioactivity Analysis
Published in 2019 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) (01-10-2019)“…We have proposed a machine learning model for efficient gamma-ray spectrometry for environmental recovery from the Fukushima Daiichi Power Plant Accident. In…”
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Conference Proceeding -
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Altered Reactivity of Superoxide Dismutase in Familial Amyotrophic Lateral Sclerosis
Published in Science (American Association for the Advancement of Science) (26-01-1996)“…A subset of individuals with familial amyotrophic lateral sclerosis (FALS) possesses dominantly inherited mutations in the gene that encodes copper-zinc…”
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Journal Article -
11
Directed Evolution of the Escherichia coli cAMP Receptor Protein at the cAMP Pocket
Published in The Journal of biological chemistry (30-10-2015)“…The Escherichia coli cAMP receptor protein (CRP) requires cAMP binding to undergo a conformational change for DNA binding and transcriptional regulation. Two…”
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12
Two novel nodal-related genes initiate early inductive events in Xenopus Nieuwkoop center
Published in Development (Cambridge) (15-12-2000)“…In vertebrates, Nodal-related protein plays crucial roles in mesoderm and endoderm induction. Here we describe two novel Xenopus nodal-related genes, Xnr5 and…”
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13
Cellular Prion Protein Combined with Galectin-3 and -6 Affects the Infectivity Titer of an Endogenous Retrovirus Assayed in Hippocampal Neuronal Cells
Published in PloS one (09-12-2016)“…Prion diseases are infectious and fatal neurodegenerative diseases which require the cellular prion protein, PrPC, for development of diseases. The current…”
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Journal Article -
14
Introduction of multiple γ-ray detection to charged particle activation analysis
Published in Journal of radioanalytical and nuclear chemistry (01-12-2017)“…Charged particle activation analysis (CPAA) is a rapid method with high accuracy which can analyze multi-elements simultaneously. Since multiple γ-ray…”
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15
Pesticide‐mediated disruption of spotted wing Drosophila flight response to raspberries
Published in Journal of applied entomology (1986) (01-06-2018)“…The disruption of chemical communication between insects and host plants may take place due to an interference with the signal‐emitting host plant, or the…”
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16
Dynamic nuclear self-polarization for measurements of nuclear magnetic moments
Published in Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms (15-12-2013)“…•Dynamic nuclear self-polarization (DYNASP) is a phenomenon of semiconductors.•Large nuclear polarization is obtained in DYNASP.•DYNASP is useful for the…”
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17
Probabilistic estimation of long-term volcanic hazard with assimilation of geophysics and tectonic data
Published in Journal of volcanology and geothermal research (01-08-2012)“…Risk assessments in relation to the siting of potential geological repositories require the estimation of long-term volcanic hazard. Owing to their tectonic…”
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18
Evaluation of health and quality of life in apheresis patients – data from the WAA register
Published in Transfusion and apheresis science (01-10-2019)“…: The World Apheresis Association (WAA) register contains data from more than 89 000 apheresis procedures in more than 12,000 patients. The aim of this study…”
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19
TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity
Published in Oncogene (18-03-2010)“…Germline TSC1 or TSC2 mutations cause tuberous sclerosis complex (TSC), a hamartoma syndrome with lung involvement. To explore the potential interaction…”
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Journal Article -
20
Loss of in Vitro Metal Ion Binding Specificity in Mutant Copper-Zinc Superoxide Dismutases Associated with Familial Amyotrophic Lateral Sclerosis
Published in The Journal of biological chemistry (14-01-2000)“…The presence of the copper ion at the active site of human wild type copper-zinc superoxide dismutase (CuZnSOD) is essential to its ability to catalyze the…”
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