Search Results - "Goto, Fumio"

Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features by Kawai-Kitahata, Fukiko, Asahina, Yasuhiro, Tanaka, Shinji, Kakinuma, Sei, Murakawa, Miyako, Nitta, Sayuri, Watanabe, Takako, Otani, Satoshi, Taniguchi, Miki, Goto, Fumio, Nagata, Hiroko, Kaneko, Shun, Tasaka-Fujita, Megumi, Nishimura-Sakurai, Yuki, Azuma, Seishin, Itsui, Yasuhiro, Nakagawa, Mina, Tanabe, Minoru, Takano, Shinichi, Fukasawa, Mitsuharu, Sakamoto, Minoru, Maekawa, Shinya, Enomoto, Nobuyuki, Watanabe, Mamoru

“…Background and Aims Genetic alterations in specific genes are critical events in carcinogenesis and hepatocellular carcinoma (HCC) progression. However, the…”
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Efficacy of additional radiofrequency ablation after transcatheter arterial chemoembolization for intermediate hepatocellular carcinoma by Azuma, Seishin, Asahina, Yasuhiro, Nishimura-Sakurai, Yuki, Kakinuma, Sei, Kaneko, Shun, Nagata, Hiroko, Goto, Fumio, Ootani, Satoshi, Kawai-Kitahata, Fukiko, Taniguchi, Miki, Murakawa, Miyako, Watanabe, Takako, Tasaka-Fujita, Megumi, Itsui, Yasuhiro, Nakagawa, Mina, Watanabe, Mamoru

“…Aim For intermediate hepatocellular carcinoma (HCC), transcatheter arterial chemoembolization (TACE) therapy is recommended in the guidelines as a monotherapy,…”
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Protein purification and cloning of diacylglycerol lipase from rat brain by Aso, Chizu, Araki, Mari, Ohshima, Noriyasu, Tatei, Kazuaki, Hirano, Tohko, Obinata, Hideru, Kishi, Mikiko, Kishimoto, Koji, Konishi, Akimitsu, Goto, Fumio, Sugimoto, Hiroyuki, Izumi, Takashi

“…Diacylglycerol (DG) lipase, which hydrolyses 1-stearoyl-2-arachidonyl-sn-glycerol to produce an endocannabinoid, 2-arachidonoylglycerol, was purified from the…”
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The Neurotoxicity of Local Anesthetics on Growing Neurons: A Comparative Study of Lidocaine, Bupivacaine, Mepivacaine, and Ropivacaine by Radwan, Inas A. M., Saito, Shigeru, Goto, Fumio

“…Local anesthetics can be neurotoxic. To test the hypothesis that exposure to local anesthetics produces morphological changes in growing neurons and to compare…”
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Peripheral 5-HT2A receptor antagonism attenuates primary thermal hyperalgesia and secondary mechanical allodynia after thermal injury in rats by SASAKI, Masayuki, OBATA, Hideaki, KAWAHARA, Kunie, SAITO, Shigeru, GOTO, Fumio

“…Inflammation or injury of peripheral tissue causes release of chemical mediators, including 5-hydroxytryptamine (5-HT), which is involved in the facilitation…”
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Bone morphogenetic protein‐4 modulates proliferation and terminal differentiation of fetal hepatic stem/progenitor cells by Goto, Fumio, Kakinuma, Sei, Miyoshi, Masato, Tsunoda, Tomoyuki, Kaneko, Shun, Sato, Ayako, Asano, Yu, Otani, Satoshi, Azuma, Seishin, Nagata, Hiroko, Kawai‐Kitahata, Fukiko, Murakawa, Miyako, Nitta, Sayuri, Itsui, Yasuhiro, Nakagawa, Mina, Asahina, Yasuhiro, Watanabe, Mamoru

“…Aim Fetal hepatic stem/progenitor cells, called hepatoblasts, play central roles in liver organogenesis; however, molecular mechanisms regulating proliferation…”
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Matrix metalloproteinase-14 mediates formation of bile ducts and hepatic maturation of fetal hepatic progenitor cells by Otani, Satoshi, Kakinuma, Sei, Kamiya, Akihide, Goto, Fumio, Kaneko, Shun, Miyoshi, Masato, Tsunoda, Tomoyuki, Asano, Yu, Kawai-Kitahata, Fukiko, Nitta, Sayuri, Nakata, Toru, Okamoto, Ryuichi, Itsui, Yasuhiro, Nakagawa, Mina, Azuma, Seishin, Asahina, Yasuhiro, Yamaguchi, Tomoyuki, Koshikawa, Naohiko, Seiki, Motoharu, Nakauchi, Hiromitsu, Watanabe, Mamoru

“…Fetal hepatic stem/progenitor cells, called hepatoblasts, play central roles in liver development; however, the molecular mechanisms regulating the phenotype…”
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Factors associated with postoperative cognitive dysfunction in patients undergoing cardiac surgery by Kadoi, Yuji, Goto, Fumio

“…Central nervous system complications continue to be major causes of morbidity and mortality after cardiac surgery. The purpose of this study was to identify…”
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The neurotoxicity of local anesthetics on growing neurons: A comparative study of lidocaine, bupivacaine, mepivacaine, and ropivacaine by RADWAN, Inas A. M, SAITO, Shigeru, GOTO, Fumio

“…Local anesthetics can be neurotoxic. To test the hypothesis that exposure to local anesthetics produces morphological changes in growing neurons and to compare…”
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A Randomized, Double-Blind, Placebo-Controlled Study of Fentanyl Buccal Tablets for Breakthrough Pain: Efficacy and Safety in Japanese Cancer Patients by Kosugi, Toshifumi, MD, PhD, Hamada, Sasagu, MD, Takigawa, Chizuko, MD, Shinozaki, Katsunori, MD, PhD, Kunikane, Hiroshi, MD, PhD, Goto, Fumio, MD, PhD, Tanda, Shigeru, MD, PhD, Shima, Yasuo, MD, Yomiya, Kinomi, MD, Matoba, Motohiro, MD, PhD, Adachi, Isamu, MD, PhD, Yoshimoto, Tetsusuke, MD, PhD, Eguchi, Kenji, MD, PhD

“…Abstract Context Rapid-onset opioids for treating breakthrough pain (BTP) in patients with cancer are needed in the Japanese care setting. Objectives To…”
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The Monoamine-Mediated Antiallodynic Effects of Intrathecally Administered Milnacipran, a Serotonin Noradrenaline Reuptake Inhibitor, in a Rat Model of Neuropathic Pain by Obata, Hideaki, Saito, Shigeru, Koizuka, Shiro, Nishikawa, Koichi, Goto, Fumio

“…Antidepressants are often used to treat neuropathic pain. In the present study, we determined the antiallodynic effects of selective monoamine reuptake…”
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Actions of propofol on substantia gelatinosa neurones in rat spinal cord revealed by in vitro and in vivo patch-clamp recordings by Takazawa, Tomonori, Furue, Hidemasa, Nishikawa, Koichi, Uta, Daisuke, Takeshima, Kaori, Goto, Fumio, Yoshimura, Megumu

“…Propofol, an intravenous general anaesthetic, exerts anaesthetic actions through interaction with γ‐aminobutyric acid type A (GABAA) receptors in the…”
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Somatotopy in human primary somatosensory cortex in pain system by OGINO, Yuichi, NEMOTO, Hidenori, GOTO, Fumio

“…Compared with somatotopical organization (somatotopy) in the postcentral gyrus in the tactile system, somatotopy in the pain system is not well understood. The…”
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Human kidneys play an important role in the elimination of propofol by TAKIZAWA, Daisuke, HIRAOKA, Haruhiko, GOTO, Fumio, YAMAMOTO, Koujirou, HORIUCHI, Ryuya

“…Extrahepatic clearance of propofol has been suggested because its total body clearance exceeds hepatic blood flow. However, it remains uncertain which organs…”
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Breakthrough pain management using fentanyl buccal tablet (FBT) in combination with around-the-clock (ATC) opioids based on the efficacy and safety of FBT, and its relationship with ATC opioids: results from an open-label, multi-center study in Japanese cancer patients with detailed evaluation by Takigawa, Chizuko, Goto, Fumio, Tanda, Shigeru, Shima, Yasuo, Yomiya, Kinomi, Matoba, Motohiro, Adachi, Isamu, Yoshimoto, Tetsusuke, Eguchi, Kenji

“…Rapid analgesic onset opioids, particularly fentanyl buccal tablet, is preferable for managing breakthrough pain. The efficacy and safety of fentanyl buccal…”
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Effects of 5-HT2 and 5-HT3 receptors on the modulation of nociceptive transmission in rat spinal cord according to the formalin test by SASAKI, Masayuki, ISHIZAKI, Keiji, OBATA, Hideaki, GOTO, Fumio

“…We used the formalin test to clarify the 5-hydroxytryptamine (5-HT) receptor subtypes involved in the modulation of spinal nociceptive transmission in rats…”
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Sevoflurane anesthesia did not affect postoperative cognitive dysfunction in patients undergoing coronary artery bypass graft surgery by Kadoi, Yuji, Goto, Fumio

“…The purpose of this study was to retrospectively examine whether sevoflurane anesthesia had any ameliorative effects on postoperative cognitive dysfunction in…”
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Propofol induces growth cone collapse and neurite retractions in chick explant culture by Al-Jahdari, Wael S, Saito, Shigeru, Nakano, Takashi, Goto, Fumio

“…Propofol neurotoxicity has been demonstrated in several cell culture systems. This study was undertaken to determine whether propofol has neurotoxic effects on…”
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Prediction of total propofol clearance based on enzyme activities in microsomes from human kidney and liver by AL-JAHDARI, Wael S, YAMAMOTO, Koujirou, HIRAOKA, Haruhiko, NAKAMURA, Katsunori, GOTO, Fumio, HORIUCHI, Ryuya

“…Propofol is commonly used for anesthesia and sedation in intensive care units. Approximately 53% of injected propofol is excreted in the urine as the…”
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Diabetic patients have an impaired cerebral vasodilatory response to hypercapnia under propofol anesthesia by KADOI, Yuji, HINOHARA, Hiroshi, KUNIMOTO, Fumio, SAITO, Shigeru, IDE, Masanobu, HIRAOKA, Haruhiko, KAWAHARA, Fuminori, GOTO, Fumio

“…The purpose of this study was to examine the effects of diabetes mellitus and its severity on the cerebral vasodilatory response to hypercapnia. Thirty…”
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