Search Results - "Goswami, Ritabrita"

Direct Cytosolic Delivery of Proteins through Coengineering of Proteins and Polymeric Delivery Vehicles by Lee, Yi-Wei, Luther, David C, Goswami, Ritabrita, Jeon, Taewon, Clark, Vincent, Elia, James, Gopalakrishnan, Sanjana, Rotello, Vincent M

“…Nanocarrier-mediated protein delivery is a promising strategy for fundamental research and therapeutic applications. However, the efficacy of the current…”
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Accessing Intracellular Targets through Nanocarrier-Mediated Cytosolic Protein Delivery by Goswami, Ritabrita, Jeon, Taewon, Nagaraj, Harini, Zhai, Shumei, Rotello, Vincent M.

“…Protein-based therapeutics have unique therapeutic potential due to their specificity, potency, and low toxicity. The vast majority of intracellular…”
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All-Natural Gelatin-Based Nanoemulsion Loaded with TLR 7/8 Agonist for Efficient Modulation of Macrophage Polarization for Immunotherapy by Goswami, Ritabrita, Nabawy, Ahmed, Jiang, Mingdi, Cicek, Yagiz Anil, Hassan, Muhammad Aamir, Nagaraj, Harini, Zhang, Xianzhi, Rotello, Vincent M

“…Macrophages are multifunctional immune cells essential for both innate and adaptive immune responses. Tumor-associated macrophages (TAMs) often adopt a…”
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Direct Cytosolic Delivery of Citraconylated Proteins by Goswami, Ritabrita, Lehot, Victor, Çiçek, Yağız Anıl, Nagaraj, Harini, Jeon, Taewon, Nguyen, Terry, Fedeli, Stefano, Rotello, Vincent M

“…Current intracellular protein delivery strategies face the challenge of endosomal entrapment and consequent degradation of protein cargo. Methods to…”
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Engineered Bacteriophage-Polymer Nanoassemblies for Treatment of Wound Biofilm Infections by Park, Jungmi, Hassan, Muhammad Aamir, Nabawy, Ahmed, Li, Cheng Hsuan, Jiang, Mingdi, Parmar, Krupa, Reddivari, Annika, Goswami, Ritabrita, Jeon, Taewon, Patel, Robin, Rotello, Vincent M.

“…The antibacterial efficacy and specificity of lytic bacteriophages (phages) make them promising therapeutics for treatment of multidrug-resistant bacterial…”
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Protein Delivery: If Your GFP (or Other Small Protein) Is in the Cytosol, It Will Also Be in the Nucleus by Luther, David C, Jeon, Taewon, Goswami, Ritabrita, Nagaraj, Harini, Kim, Dongkap, Lee, Yi-Wei, Rotello, Vincent M

“…Intracellular protein delivery is a transformative tool for biologics research and medicine. Delivery into the cytosol allows proteins to diffuse throughout…”
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Cytosolic Protein Delivery Using Modular Biotin–Streptavidin Assembly of Nanocomposites by Luther, David C., Lee, Yi-Wei, Nagaraj, Harini, Clark, Vincent, Jeon, Taewon, Goswami, Ritabrita, Gopalakrishnan, Sanjana, Fedeli, Stefano, Jerome, William, Elia, James L., Rotello, Vincent M.

“…Current strategies for the delivery of proteins into cells face general challenges of endosomal entrapment and concomitant degradation of protein cargo…”
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Multiplexed Quantitative Screening of the Cellular Uptake of Proteins Delivered by Polymeric Nanocarriers by Agrohia, Dheeraj K., Goswami, Ritabrita, Çiçek, Yağız Anıl, Tabaru, Neslihan E., Brady, Trisha W., Rotello, Vincent M., Vachet, Richard W.

“…Proteins are important therapeutic agents, yet better methods are needed to deliver them inside of cells. Polymeric nanocarriers (PNCs) are versatile materials…”
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Suborgan Level Quantitation of Proteins in Tissues Delivered by Polymeric Nanocarriers by Agrohia, Dheeraj K., Goswami, Ritabrita, Jantarat, Teerapong, Çiçek, Yağız Anil, Thongsukh, Korndanai, Jeon, Taewon, Bell, Jonathan M., Rotello, Vincent M., Vachet, Richard W.

“…Amidst the rapid growth of protein therapeutics as a drug class, there is an increased focus on designing systems to effectively deliver proteins to target…”
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Antimicrobial-loaded biodegradable nanoemulsions for efficient clearance of intracellular pathogens in bacterial peritonitis by Makabenta, Jessa Marie V., Nabawy, Ahmed, Chattopadhyay, Aritra Nath, Park, Jungmi, Li, Cheng-Hsuan, Goswami, Ritabrita, Luther, David C., Huang, Rui, Hassan, Muhammad Aamir, Rotello, Vincent M.

“…Intracellular pathogenic bacteria use immune cells as hosts for bacterial replication and reinfection, leading to challenging systemic infections including…”
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Engineered Polymer–siRNA Polyplexes Provide Effective Treatment of Lung Inflammation by Jeon, Taewon, Luther, David C., Goswami, Ritabrita, Bell, Charlotte, Nagaraj, Harini, Cicek, Yagiz Anil, Huang, Rui, Mas-Rosario, Javier A., Elia, James L., Im, Jungkyun, Lee, Yi-Wei, Liu, Yuanchang, Scaletti, Federica, Farkas, Michelle E., Mager, Jesse, Rotello, Vincent M.

“…Uncontrolled inflammation is responsible for acute and chronic diseases in the lung. Regulating expression of pro-inflammatory genes in pulmonary tissue using…”
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Direct Cytosolic Delivery of Proteins Using Lyophilized and Reconstituted Polymer-Protein Assemblies by Luther, David C., Nagaraj, Harini, Goswami, Ritabrita, Çiçek, Yağız Anıl, Jeon, Taewon, Gopalakrishnan, Sanjana, Rotello, Vincent M.

“…Purpose Cytosolic delivery of proteins accesses intracellular targets for chemotherapy and immunomodulation. Current delivery systems utilize inefficient…”
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Bioorthogonal nanozymes for breast cancer imaging and therapy by Zhang, Xianzhi, Liu, Yuanchang, Doungchawee, Jeerapat, Castellanos-García, Laura J., Sikora, Kristen N., Jeon, Taewon, Goswami, Ritabrita, Fedeli, Stefano, Gupta, Aarohi, Huang, Rui, Hirschbiegel, Cristina-Maria, Cao-Milán, Roberto, Majhi, Prabin K.D., Cicek, Yagiz Anil, Liu, Liang, Jerry, D. Joseph, Vachet, Richard W., Rotello, Vincent M.

“…Bioorthogonal catalysis via transition metal catalysts (TMCs) enables the generation of therapeutics locally through chemical reactions not accessible by…”
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Engineered Zwitterionic Diblock Copolymer‐siRNA Polyplexes Provide Highly Effective Treatment of Triple‐Negative Breast Cancer in a 4T1 Murine Model by Jeon, Taewon, Goswami, Ritabrita, Nagaraj, Harini, Cicek, Yagiz Anil, Lehot, Victor, Welton, Janelle, Bell, Charlotte J., Park, Jungmi, Luther, David C., Im, Jungkyun, Rotello, Caren M., Mager, Jesse, Rotello, Vincent M.

“…Self‐assembly of small interfering RNA (siRNA) with a block copolymer featuring guanidinium and zwitterion functionalized blocks generates core‐shell‐like…”
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Direct Cytosolic Delivery of Proteins Through Co-Engineering of Proteins and Polymeric Delivery Vehicles by Lee, Yi-Wei, Luther, David C., Goswami, Ritabrita, Jeon, Taewon, Clark, Vincent, Elia, James, Gopalakrishnan, Sanjana, Rotello, Vincent M.

“…Nanocarrier-mediated protein delivery is a promising strategy for fundamental research and therapeutic applications. However, the efficacy of current platforms…”
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Correction to “Direct Cytosolic Delivery of Proteins through Coengineering of Proteins and Polymeric Delivery Vehicles” by Lee, Yi-Wei, Luther, David C, Goswami, Ritabrita, Jeon, Taewon, Clark, Vincent, Elia, James, Gopalakrishnan, Sanjana, Rotello, Vincent M

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Selective treatment of intracellular bacterial infections using host cell-targeted bioorthogonal nanozymes by Hardie, Joseph, Makabenta, Jessa Marie, Gupta, Aarohi, Huang, Rui, Cao-Milán, Roberto, Goswami, Ritabrita, Zhang, Xianzhi, Abdulpurkar, Parvati, Farkas, Michelle E, Rotello, Vincent M

“…Intracellular bacterial infections are difficult to treat, and in the case of and related infections, can be life threatening. Antibiotic treatments for…”
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Engineering of bioorthogonal polyzymes through polymer sidechain design by Hirschbiegel, Cristina‐Maria, Goswami, Ritabrita, Chakraborty, Soham, Noonan, Cedar, Pham, Edward, Nagaraj, Harini, Ndugire, William, Fedeli, Stefano, Rotello, Vincent M.

“…Synthetic polymer scaffolds can encapsulate transition metal catalysts (TMCs) to provide bioorthogonal nanocatalysts. These “polyzymes” catalyze the in situ…”
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