Search Results - "Goswami, Chirayu P."

Cancer Affects microRNA Expression, Release, and Function in Cardiac and Skeletal Muscle by DAOHONG CHEN, GOSWAMI, Chirayu P, BURNETT, Riesa M, ANJANAPPA, Manjushree, BHAT-NAKSHATRI, Poornima, MULLER, William, NAKSHATRI, Harikrishna

“…Circulating microRNAs (miRNA) are emerging as important biomarkers of various diseases, including cancer. Intriguingly, circulating levels of several miRNAs…”
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Molecular Insights of Pathways Resulting from Two Common PIK3CA Mutations in Breast Cancer by Bhat-Nakshatri, Poornima, Goswami, Chirayu P, Badve, Sunil, Magnani, Luca, Lupien, Mathieu, Nakshatri, Harikrishna

“…The PI3K pathway is activated in approximately 70% of breast cancers. PIK3CA gene mutations or amplifications that affect the PI3K p110α subunit account for…”
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Persistent upregulation of U6:SNORD44 small RNA ratio in the serum of breast cancer patients by Appaiah, Hitesh N, Goswami, Chirayu P, Mina, Lida A, Badve, Sunil, Sledge, Jr, George W, Liu, Yunlong, Nakshatri, Harikrishna

“…Serum microRNAs have the potential to be valuable biomarkers of cancer. This investigation addresses two issues that impact their utility: a) appropriate…”
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Organ-specific adaptive signaling pathway activation in metastatic breast cancer cells by Burnett, Riesa M, Craven, Kelly E, Krishnamurthy, Purna, Goswami, Chirayu P, Badve, Sunil, Crooks, Peter, Mathews, William P, Bhat-Nakshatri, Poornima, Nakshatri, Harikrishna

“…Breast cancer metastasizes to bone, visceral organs, and/or brain depending on the subtype, which may involve activation of a host organ-specific signaling…”
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HLA-genotyping of clinical specimens using Ion Torrent-based NGS by Barone, Jonathan C, Saito, Katsuyuki, Beutner, Karl, Campo, Maria, Dong, Wei, Goswami, Chirayu P, Johnson, Erica S, Wang, Zi-Xuan, Hsu, Susan

“…Abstract We have evaluated and validated the NXType™ workflow (One Lambda, Inc.) and the accompanying TypeStream™ software on the Ion Torrent Next Generation…”
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Gene expression profiles among murine strains segregate with distinct differences in the progression of radiation-induced lung disease by Jackson, Isabel L, Baye, Fitsum, Goswami, Chirayu P, Katz, Barry P, Zodda, Andrew, Pavlovic, Radmila, Gurung, Ganga, Winans, Don, Vujaskovic, Zeljko

“…Molecular mechanisms underlying development of acute pneumonitis and/or late fibrosis following thoracic irradiation remain poorly understood. Here, we…”
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Establishment and characterization of a novel cell line derived from human thymoma AB tumor by Gökmen-Polar, Yesim, Sanders, Kerry L, Goswami, Chirayu P, Cano, Oscar D, Zaheer, Narjis A, Jain, Rohit K, Kesler, Kenneth A, Nelson, Robert P, Vance, Gail H, Smith, Danielle, Li, Lang, Cardoso, Angelo A, Badve, Sunil, Loehrer, Patrick J, Sledge, George W

“…Thymomas are low-grade epithelial tumors of the anterior mediastinum. The complexity of the disease and the lack of in vitro and in vivo models hamper the…”
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Prostate cancer sheds the αvβ3 integrin in vivo through exosomes by Krishn, Shiv Ram, Singh, Amrita, Bowler, Nicholas, Duffy, Alexander N., Friedman, Andrea, Fedele, Carmine, Kurtoglu, Senem, Tripathi, Sushil K., Wang, Kerith, Hawkins, Adam, Sayeed, Aejaz, Goswami, Chirayu P., Thakur, Madhukar L., Iozzo, Renato V., Peiper, Stephen C., Kelly, William K., Languino, Lucia R.

“…The αvβ3 integrin has been shown to promote aggressive phenotypes in many types of cancers, including prostate cancer. We show that GFP-labeled αvβ3 derived…”
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Splicing factor ESRP1 controls ER‐positive breast cancer by altering metabolic pathways by Gökmen‐Polar, Yesim, Neelamraju, Yaseswini, Goswami, Chirayu P, Gu, Yuan, Gu, Xiaoping, Nallamothu, Gouthami, Vieth, Edyta, Janga, Sarath C, Ryan, Michael, Badve, Sunil S

“…The epithelial splicing regulatory proteins 1 and 2 (ESRP1 and ESRP2) control the epithelial‐to‐mesenchymal transition (EMT) splicing program in cancer…”
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Identification of FDA-approved Drugs Targeting Breast Cancer Stem Cells Along With Biomarkers of Sensitivity by Bhat-Nakshatri, Poornima, Goswami, Chirayu P., Badve, Sunil, Sledge, George W., Nakshatri, Harikrishna

“…Recently developed genomics-based tools are allowing repositioning of Food and Drug Administration (FDA)-approved drugs as cancer treatments, which were…”
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Expression levels of SF3B3 correlate with prognosis and endocrine resistance in estrogen receptor-positive breast cancer by Gökmen-Polar, Yesim, Neelamraju, Yaseswini, Goswami, Chirayu P, Gu, Xiaoping, Nallamothu, Gouthami, Janga, Sarath Chandra, Badve, Sunil

“…De novo or acquired resistance to endocrine therapy limits its utility in a significant number of estrogen receptor-positive (ER-positive) breast cancers. It…”
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Validation of a next-generation-sequencing cancer panel for use in the clinical laboratory by Simen, Birgitte B, Yin, Lina, Goswami, Chirayu P, Davis, Kathleen O, Bajaj, Renu, Gong, Jerald Z, Peiper, Stephen C, Johnson, Erica S, Wang, Zi-Xuan

“…Next-generation sequencing allows for high-throughput processing and sensitive variant detection in multiple genes from small samples. For many diseases,…”
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Identification and validation of genes with expression patterns inverse to multiple metastasis suppressor genes in breast cancer cell lines by Marino, Natascia, Collins, Joshua W., Shen, Changyu, Caplen, Natasha J., Merchant, Anand S., Gökmen-Polar, Yesim, Goswami, Chirayu P., Hoshino, Takashi, Qian, Yongzhen, Sledge, George W., Steeg, Patricia S.

“…Metastasis suppressor genes (MSGs) have contributed to an understanding of regulatory pathways unique to the lethal metastatic process. When re-expressed in…”
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A molecular signature of normal breast epithelial and stromal cells from Li-Fraumeni syndrome mutation carriers by Herbert, Brittney-Shea, Chanoux, Rebecca A, Liu, Yunlong, Baenziger, Peter H, Goswami, Chirayu P, McClintick, Jeanette N, Edenberg, Howard J, Pennington, Robert E, Lipkin, Steven M, Kopelovich, Levy

“…Specific changes in gene expression during cancer initiation should enable discovery of biomarkers for risk assessment, early detection and targets for…”
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Gene Expression Analysis Reveals Distinct Pathways of Resistance to Bevacizumab in Xenograft Models of Human ER-Positive Breast Cancer by Gökmen-Polar, Yesim, Goswami, Chirayu P, Toroni, Rachel A, Sanders, Kerry L, Mehta, Rutika, Sirimalle, Usha, Tanasa, Bogdan, Shen, Changyu, Li, Lang, Ivan, Mircea, Badve, Sunil, Sledge, Jr, George W

“…Bevacizumab, the recombinant antibody targeting vascular endothelial growth factor (VEGF), improves progression-free but not overall survival in metastatic…”
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PROGgene: gene expression based survival analysis web application for multiple cancers by Goswami, Chirayu Pankaj, Nakshatri, Harikrishna

“…Identification of prognostic mRNA biomarkers has been done for various cancer types. The data that are published from such studies are archived in public…”
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A community computational challenge to predict the activity of pairs of compounds by Bansal, Mukesh, Yang, Jichen, Karan, Charles, Menden, Michael P, Costello, James C, Tang, Hao, Xiao, Guanghua, Li, Yajuan, Allen, Jeffrey, Zhong, Rui, Chen, Beibei, Kim, Minsoo, Wang, Tao, Heiser, Laura M, Realubit, Ronald, Mattioli, Michela, Alvarez, Mariano J, Shen, Yao, Gallahan, Daniel, Singer, Dinah, Saez-Rodriguez, Julio, Xie, Yang, Stolovitzky, Gustavo, Califano, Andrea

“…A community computational challenge generates algorithms to predict activity of drug combinations. Recent therapeutic successes have renewed interest in drug…”
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Splicing factor ESRP 1 controls ER ‐positive breast cancer by altering metabolic pathways by Gökmen‐Polar, Yesim, Neelamraju, Yaseswini, Goswami, Chirayu P, Gu, Yuan, Gu, Xiaoping, Nallamothu, Gouthami, Vieth, Edyta, Janga, Sarath C, Ryan, Michael, Badve, Sunil S

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Cancer impacts microRNA expression, release and function in cardiac and skeletal muscle by Chen, Daohong, Goswami, Chirayu P, Burnett, Riesa M, Anjanappa, Manjushree, Bhat-Nakshatri, Poornima, Muller, William, Nakshatri, Harikrishna

“…Circulating microRNAs are emerging as important biomarkers of various diseases including cancer. Intriguingly, circulating levels of several microRNAs are…”
Get full text