Search Results - "Goswami, Abhinab"
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Solubility of cinnarizine in natural deep eutectic solvent (camphor + menthol) and correlation with different solubility models
Published in Fluid phase equilibria (01-03-2024)Get full text
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Analytical Quality by Design-Driven RP-HPLC Method Conditions to Concomitantly Determine Cinnarizine and Morin Hydrate in Combined Drug Solution and Dual Drug-Loaded Formulations
Published in Journal of AOAC International (01-09-2023)“…Abstract Background The replacement of traditional oils with a camphor and menthol-based eutectic mixture is done to prepare oil-less emulsion-like dispersions…”
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Neoteric solvents for the pharmaceutical industry: an update
Published in Drug discovery today (01-07-2021)“…[Display omitted] •Regulatory and solubility issues limit the use of volatile organic compounds (VOCs) and water.•The concept of neoteric solvents thus arrives…”
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Analytical Quality-by-Design-Based Systematic Optimization of RP-HPLC Method Conditions to Analyze Simultaneously Chloroquine Phosphate and Flavopiridol in Stress-Induced Combined Drug Solution and Pharmaceutical Emulsions
Published in Journal of chromatographic science (19-08-2023)“…Abstract A design of experiments (DoE)-driven RP-HPLC method conditions was employed to analyze simultaneously chloroquine (CQ) phosphate and flavopiridol…”
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Orally Administered Drug Solubility-Enhancing Formulations: Lesson Learnt from Optimum Solubility-Permeability Balance
Published in AAPS PharmSciTech (02-02-2021)“…Although oral drug delivery is considered as most acceptable route for administering the active pharmaceutical ingredients to patients of all age-groups with…”
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On the use of linear model-based optimization to obtain optimum solubility permeability balance (OSPB) in cinnarizine-hydrotropic blends
Published in Journal of molecular liquids (01-07-2023)“…[Display omitted] •Various hydrotropes capable of augmenting cinnarizine’s solubility were identified.•Identifying the existence of solubility-permeability…”
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Application of Design of Experiments® Approach-Driven Artificial Intelligence and Machine Learning for Systematic Optimization of Reverse Phase High Performance Liquid Chromatography Method to Analyze Simultaneously Two Drugs (Cyclosporin A and Etodolac) in Solution, Human Plasma, Nanocapsules, and Emulsions
Published in AAPS PharmSciTech (13-05-2021)“…The objectives of current investigation are (1) to find out wavelength of maximum absorbance (λ max ) for combined cyclosporin A and etodolac solution followed…”
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Intratympanic injections made from eutectic liquid (camphor and menthol)-based oil-less emulsions containing morin hydrate-lipoid E80 complex: An approach to augment drug permeation into inner ear region in a healthy rabbit model
Published in Journal of drug delivery science and technology (01-12-2024)“…Morin hydrate (MH, flavonols of plants, family-Moraceae) promotes inner ear stem cell survival and differentiation process to preserve the healthy hearing…”
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Intratympanic injections of emulsion-like dispersions to augment cinnarizine amount in a healthy rabbit inner ear model
Published in Nanomedicine (London, England) (2024)“…To investigate eutectic liquid-based emulsion-like dispersions for intratympanic injections to augment cinnarizine permeability across round window membrane in…”
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Studies on cationic ocular emulsions containing bipartitioned oil droplets to codeliver cyclosporin A and etodolac
Published in Nanomedicine (London, England) (2024)“…To prepare ocular emulsions containing bipartitioned oil droplets to entrap cyclosporin A (0.05% w/w) and etodolac (0.2% w/w) by using castor, olive and…”
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Dual Delivery of Cyclosporin A and Etodolac Using Polymeric Nanocapsules in a Rabbit Eye Model: Ocular Biodistribution and Pharmacokinetic Study
Published in Journal of ocular pharmacology and therapeutics (01-12-2022)“…Commercially available eye drops are loaded only with a single drug. By using the polymeric nanocapsules, dual delivery of 0.05% w/w cyclosporin A (CsA) and…”
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From co-delivery to synergistic anti-inflammatory effect: Studies on chitosan-stabilized Janus emulsions having chloroquine phosphate and flavopiridol in Complete Freund's Adjuvant induced arthritis rat model
Published in International journal of biological macromolecules (01-02-2024)“…For the first time, the co-delivery of chloroquine phosphate and flavopiridol by intra-articular route was achieved to provide local joint targeting in…”
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Intriguing of pharmaceutical product development processes with the help of artificial intelligence and deep/machine learning or artificial neural network
Published in Journal of drug delivery science and technology (01-09-2023)“…The objectives of current review are (1) to provide a historical overview of artificial intelligence and deep/machine learning (AI & D/ML) or Artificial Neural…”
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Studies on spray dried topical ophthalmic emulsions containing cyclosporin A (0.05% w/w): systematic optimization, in vitro preclinical toxicity and in vivo assessments
Published in Drug delivery and translational research (01-06-2023)“…Cyclosporin A (CsA, 0.05% w/w)–loaded positively charged emulsions were prepared based on castor oil, chitosan, poloxamer 188, glycerin and double-distilled…”
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