Search Results - "Gossye, Valerie"

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    An anti‐inflammatory selective glucocorticoid receptor modulator preserves osteoblast differentiation by Rauch, Alexander, Gossye, Valerie, Bracke, Debby, Gevaert, Elien, Jacques, Peggy, Van Beneden, Katrien, Vandooren, Bernard, Rauner, Martina, Hofbauer, Lorenz C., Haegeman, Guy, Elewaut, Dirk, Tuckermann, Jan P., De Bosscher, Karolien

    Published in The FASEB journal (01-04-2011)
    “…ABSTRACT Glucocorticoids (GCs) are in widespread use to treat inflammatory bone diseases, such as rheumatoid arthritis (RA). Their anti‐inflammatory efficacy,…”
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    Journal Article
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    Therapeutic implications of the nuclear factor-kappaB/nuclear receptor cross-talk by Gossye, Valerie, Haegeman, Guy, De Bosscher, Karolien

    Published in Frontiers in bioscience (01-05-2008)
    “…More and more evidence reveals that the transcription factor NF-kappaB plays a critical role in tumor development and progression and that it may constitute…”
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    Compound A, a Selective Glucocorticoid Receptor Modulator, Enhances Heat Shock Protein Hsp70 Gene Promoter Activation. e69115 by Beck, Ilse M, Drebert, Zuzanna J, Hoya-Arias, Ruben, Bahar, Ali A, Devos, Michael, Clarisse, Dorien, Desmet, Sofie, Bougarne, Nadia, Ruttens, Bart, Gossye, Valerie

    Published in PloS one (01-07-2013)
    “…Compound A possesses glucocorticoid receptor (GR)-dependent anti-inflammatory properties. Just like classical GR ligands, Compound A can repress NF- Kappa…”
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    Differential mechanism of NF‐κB inhibition by two glucocorticoid receptor modulators in rheumatoid arthritis synovial fibroblasts by Gossye, Valerie, Elewaut, Dirk, Bougarne, Nadia, Bracke, Debby, Van Calenbergh, Serge, Haegeman, Guy, De Bosscher, Karolien

    Published in Arthritis and rheumatism (01-11-2009)
    “…Objective To investigate and compare the molecular mechanisms by which 2 glucocorticoid receptor (GR)–activating compounds, dexamethasone (DEX) and Compound A…”
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    Differential mechanism of NF-kappaB inhibition by two glucocorticoid receptor modulators in rheumatoid arthritis synovial fibroblasts by Gossye, Valerie, Elewaut, Dirk, Bougarne, Nadia, Bracke, Debby, Van Calenbergh, Serge, Haegeman, Guy, De Bosscher, Karolien

    Published in Arthritis and rheumatism (01-11-2009)
    “…To investigate and compare the molecular mechanisms by which 2 glucocorticoid receptor (GR)-activating compounds, dexamethasone (DEX) and Compound A (CpdA),…”
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    Journal Article