Search Results - "Gossen, Jan"

Lrp5 functions in bone to regulate bone mass by Cui, Yajun, Niziolek, Paul J, MacDonald, Bryan T, Zylstra, Cassandra R, Alenina, Natalia, Robinson, Daniel R, Zhong, Zhendong, Matthes, Susann, Jacobsen, Christina M, Conlon, Ronald A, Brommage, Robert, Liu, Qingyun, Mseeh, Faika, Powell, David R, Yang, Qi M, Zambrowicz, Brian, Gerrits, Han, Gossen, Jan A, He, Xi, Bader, Michael, Williams, Bart O, Warman, Matthew L, Robling, Alexander G

“…Mutations in the Wnt co-receptor, LRP5 , lead to skeletal diseases in humans. Matthew Warman and his colleagues have now developed mutant mice with…”
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Sustained release of ancillary amounts of testosterone and alendronate from PLGA coated pericard membranes and implants to improve bone healing by van de Ven, Cindy J J M, Bakker, Nicole E C, Link, Dennis P, Geven, Edwin J W, Gossen, Jan A

“…Testosterone and alendronate have been identified as two bone healing compounds which, when combined, synergistically stimulate bone regeneration. This study…”
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Ovulation Involves the Luteinizing Hormone-Dependent Activation of Gq/11 in Granulosa Cells by Breen, Shawn M, Andric, Nebojsa, Ping, Tai, Xie, Fang, Offermans, Stefan, Gossen, Jan A, Ascoli, Mario

“…The LH receptor (LHR) activates several families of heterotrimeric G proteins, but only the activation of Gs and subsequent generation of cAMP are universally…”
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Ovulation involves the luteinizing hormone-dependent activation of G(q/11) in granulosa cells by Breen, Shawn M, Andric, Nebojsa, Ping, Tai, Xie, Fang, Offermans, Stefan, Gossen, Jan A, Ascoli, Mario

“…The LH receptor (LHR) activates several families of heterotrimeric G proteins, but only the activation of Gs and subsequent generation of cAMP are universally…”
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The Orphan Nuclear Receptor Nr5a2 Is Essential for Luteinization in the Female Mouse Ovary by Bertolin, Kalyne, Gossen, Jan, Schoonjans, Kristina, Murphy, Bruce D

“…In the ovary, the follicular granulosa cells express the nuclear receptor Nr5a2 (nuclear receptor subfamily 5 group A member 2), also known as liver receptor…”
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Granulosa Cell Specific Loss of Adar in Mice Delays Ovulation, Oocyte Maturation and Leads to Infertility by Nelson, Rikki N, Chakravarthi, V Praveen, Ratri, Anamika, Hong, Xiaoman, Gossen, Jan A, Christenson, Lane K

“…Adenosine deaminases acting on RNA-(ADAR) comprise one family of RNA editing enzymes that specifically catalyze adenosine to inosine (A-to-I) editing. A…”
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Role for PADI6 and the cytoplasmic lattices in ribosomal storage in oocytes and translational control in the early mouse embryo by Yurttas, Piraye, Vitale, Alejandra M, Fitzhenry, Robert J, Cohen-Gould, Leona, Wu, Wenzhu, Gossen, Jan A, Coonrod, Scott A

“…The mechanisms that mediate the establishment of totipotency during the egg-to-embryo transition in mammals remain poorly understood. However, it is clear that…”
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Supercritical carbon dioxide decellularised pericardium: Mechanical and structural characterisation for applications in cardio-thoracic surgery by Halfwerk, Frank R, Rouwkema, Jeroen, Gossen, Jan A, Grandjean, Jan G

“…Many biomaterials are used in cardio-thoracic surgery with good short-term results. However, calcification, dehiscence, and formation of scar tissue are…”
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Loss of GATA-6 and GATA-4 in Granulosa Cells Blocks Folliculogenesis, Ovulation, and Follicle Stimulating Hormone Receptor Expression Leading to Female Infertility by Bennett, Jill, Wu, Yan-Guang, Gossen, Jan, Zhou, Ping, Stocco, Carlos

“…Single GATA-6 (G6gcko), GATA-4 (G4gcko), and double GATA-4/6 (G4/6gcko) granulosa cell-specific knockout mice were generated to further investigate the role of…”
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Mice Deficient for Soluble Adenylyl Cyclase Are Infertile because of a Severe Sperm-Motility Defect by Esposito, Gloria, Jaiswal, Byjay S., Xie, Fang, Magda A. M. Krajnc-Franken, Tamara J. A. A. Robben, Strik, Ankie M., Kuil, Cor, Ria L. A. Philipsen, van Duin, Marcel, Conti, Marco, Gossen, Jan A., Beavo, Joseph A.

“…To acquire the ability to fertilize, spermatozoa undergo complex, but at present poorly understood, activation processes. The intracellular rise of cAMP…”
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Soluble adenylyl cyclase (sAC) is indispensable for sperm function and fertilization by Xie, Fang, Garcia, Manuel A., Carlson, Anne E., Schuh, Sonya M., Babcock, Donner F., Jaiswal, Bijay S., Gossen, Jan A., Esposito, Gloria, van Duin, Marcel, Conti, Marco

“…We previously demonstrated that male mice deficient in the soluble adenylyl cyclase (sAC) are sterile and produce spermatozoa with deficits in progressive…”
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Differential Functions of the Aurora-B and Aurora-C Kinases in Mammalian Spermatogenesis by Kimmins, Sarah, Crosio, Claudia, Kotaja, Noora, Hirayama, Jun, Monaco, Lucia, Höög, Christer, van Duin, Marcel, Gossen, Jan A, Sassone-Corsi, Paolo

“…The Aurora kinases are cell cycle-regulatory serine-threonine kinases that have been implicated in the function of the centrosomes, kinetechores, chromosome…”
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Functional transformation of the chromatoid body in mouse spermatids requires testis-specific serine/threonine kinases by Shang, Peng, Baarends, Willy M, Hoogerbrugge, Jos, Ooms, Marja P, van Cappellen, Wiggert A, de Jong, Antonius A.W, Dohle, Gert R, van Eenennaam, Hans, Gossen, Jan A, Grootegoed, J. Anton

“…The cytoplasmic chromatoid body (CB) organizes mRNA metabolism and small regulatory RNA pathways, in relation to haploid gene expression, in mammalian round…”
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The Testis Anion Transporter 1 (Slc26a8) is required for sperm terminal differentiation and male fertility in the mouse by Touré, Aminata, Lhuillier, Pierre, Gossen, Jan A., Kuil, Cor W., Lhôte, David, Jégou, Bernard, Escalier, Denise, Gacon, Gérard

“…The Slc26 family is a conserved family of anion transporters. In the human, their physiological relevance was highlighted with the discovery of pathogenic…”
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Early postnatal lethality and cardiovascular defects in CXCR7-deficient mice by Gerrits, Han, van Ingen Schenau, Dorette S., Bakker, Nicole E.C., van Disseldorp, Ad J.M., Strik, Ankie, Hermens, Laura S., Koenen, Tim B., Krajnc-Franken, Magda A.M., Gossen, Jan A.

“…CXCR7 is a G‐protein coupled receptor that was recently deorphanized and shown to have SDF1 and I‐TAC as high affinity ligands. Here we describe the…”
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Orphan Nuclear Receptor LRH-1 Is Required To Maintain Oct4 Expression at the Epiblast Stage of Embryonic Development by Gu, Peili, Goodwin, Bryan, Chung, Arthur C.-K., Xu, Xueping, Wheeler, David A., Price, Roger R., Galardi, Cristin, Peng, Li, Latour, Anne M., Koller, Beverly H., Gossen, Jan, Kliewer, Steven A., Cooney, Austin J.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Impaired Nipple Development and Parturition in LGR7 Knockout Mice by Krajnc-Franken, Magda A. M., van Disseldorp, Ad J. M., Koenders, Jasper E., Mosselman, Sietse, van Duin, Marcel, Gossen, Jan A.

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Distinct Spectra of Somatic Mutations Accumulated with Age in Mouse Heart and Small Intestine by Martijn E. T. Dolle, Snyder, Wendy K., Gossen, Jan A., Paul H. M. Lohman, Vijg, Jan

“…Somatic mutation accumulation has been implicated as a major cause of cancer and aging. By using a transgenic mouse model with a chromosomally integrated IacZ…”
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Evaluation of Collagen Membranes Coated with Testosterone and Alendronate to Improve Guided Bone Regeneration in Mandibular Bone Defects in Minipigs by van Oirschot, Bart A J A, Jansen, John A, van de Ven, Cindy J J M, Geven, Edwin J W, Gossen, Jan A

“…The purpose of the present study was to evaluate whether pericard collagen membranes coated with ancillary amounts of testosterone and alendronate in a…”
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Reversible infertility in a liver receptor homologue-1 (LRH-1)-knockdown mouse model by Gerrits, Han, Paradé, Marc C B C, Koonen-Reemst, Annemie M C B, Bakker, Nicole E C, Timmer-Hellings, Lenita, Sollewijn Gelpke, Maarten D, Gossen, Jan A

“…Liver receptor homologue-1 (LRH-1) is an orphan nuclear receptor that has been implicated in steroid hormone biosynthesis and fertility. Herein we describe a…”
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