Search Results - "Gosselin, H."

An Earth-sized exoplanet with a Mercury-like composition by Santerne, A., Brugger, B., Armstrong, D. J., Adibekyan, V., Lillo-Box, J., Gosselin, H., Aguichine, A., Almenara, J.-M., Barrado, D., Barros, S. C. C., Bayliss, D., Boisse, I., Bonomo, A. S., Bouchy, F., Brown, D. J. A., Deleuil, M., Delgado Mena, E., Demangeon, O., Díaz, R. F., Doyle, A., Dumusque, X., Faedi, F., Faria, J. P., Figueira, P., Foxell, E., Giles, H., Hébrard, G., Hojjatpanah, S., Hobson, M., Jackman, J., King, G., Kirk, J., Lam, K. W. F., Ligi, R., Lovis, C., Louden, T., McCormac, J., Mousis, O., Neal, J. J., Osborn, H. P., Pepe, F., Pollacco, D., Santos, N. C., Sousa, S. G., Udry, S., Vigan, A.

“…Earth, Venus, Mars and some extrasolar terrestrial planets 1 have a mass and radius that is consistent with a mass fraction of about 30% metallic core and 70%…”
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Randomized Population Pharmacokinetic Analysis and Safety of Intravenous Acetaminophen for Acute Postoperative Pain in Neonates and Infants by Hammer, Gregory B., Maxwell, Lynne G., Taicher, Brad M., Visoiu, Mihaela, Cooper, David S., Szmuk, Peter, Pheng, Leng Hong, Gosselin, Nathalie H., Lu, Jia, Devarakonda, Krishna

“…Intravenous administration of acetaminophen is an alternative to the oral and rectal routes, which may be contraindicated in particular clinical settings. This…”
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Relationship between prenatal exposure to polychlorinated biphenyls and birth weight: A systematic analysis of published epidemiological studies through a standardization of biomonitoring data by El Majidi, Naïma, Bouchard, Michèle, Gosselin, Nathalie H., Carrier, Gaétan

“…► A systematic analysis of published studies on birth weight effect of PCBs was conducted. ► Prenatal PCB exposure was standardized between epidemiological…”
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Pharmacokinetic and Pharmacodynamic Modeling To Determine the Dose of ST-246 To Protect against Smallpox in Humans by LEEDS, Janet M, FENNETEAU, Frederique, CHINSANGARAM, Jarasvech, TYAVANAGIMATT, Shanthakumar R, HRUBY, Dennis E, JORDAN, Robert, GOSSELIN, Nathalie H, MOUKSASSI, Mohamad-Samer, KASSIR, Nastya, MARIER, J. F, YALI CHEN, GROSENBACH, Doug, FRIMM, Annie E, HONEYCHURCH, Kady M

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Modeling and Experimental Studies of Obeticholic Acid Exposure and the Impact of Cirrhosis Stage by Edwards, JE, LaCerte, C, Peyret, T, Gosselin, NH, Marier, JF, Hofmann, AF, Shapiro, D

“…Obeticholic acid (OCA), a semisynthetic bile acid, is a selective and potent farnesoid X receptor (FXR) agonist in development for the treatment of chronic…”
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Item Response Theory Quantifies the Relationship Between Improvements in Serum Phosphate and Patient‐Reported Outcomes in Adults With X‐Linked Hypophosphatemia by Mehta, Krina, Gosselin, Nathalie H., Insogna, Karl, Barriere, Olivier, Quattrocchi, Emilia, Hruska, Matthew W., Marsteller, Douglas

“…Burosumab is indicated for treatment of a rare bone disease, X‐linked hypophosphatemia (XLH). The aim of this analysis was to evaluate the relationship between…”
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A randomized, double‐blind, placebo‐controlled, pharmacokinetic and pharmacodynamic study of a fixed‐dose combination of phentermine/topiramate in adolescents with obesity by Hsia, Daniel S., Gosselin, Nathalie H., Williams, Jenna, Farhat, Nada, Marier, J. F., Shih, Winnie, Peterson, Craig, Siegel, Robert

“…Aims To assess the pharmacokinetic (PK) and pharmacodynamic characteristics of VI‐0521, a fixed‐dose combination of immediate‐release phentermine (PHEN) and…”
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Translational Population‐Pharmacodynamic Modeling of a Novel Long‐Acting siRNA Therapy, Inclisiran, for the Treatment of Hypercholesterolemia by Gosselin, Nathalie H., Schuck, Virna J. A., Barriere, Olivier, Kulmatycki, Kenneth, Margolskee, Alison, Smith, Patrick, He, YanLing

“…Inclisiran is a novel N‐acetylgalactosamine (GalNAc) conjugated small‐interfering ribonucleic acid (siRNA) therapy designed to specifically target proprotein…”
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Population pharmacokinetics of bevacizumab in cancer patients with external validation by Han, Kelong, Peyret, Thomas, Marchand, Mathilde, Quartino, Angelica, Gosselin, Nathalie H., Girish, Sandhya, Allison, David E., Jin, Jin

“…Background Bevacizumab is approved for various cancers. This analysis aimed to comprehensively evaluate bevacizumab pharmacokinetics and the influence of…”
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Incremental kernel learning for active image retrieval without global dictionaries by Gosselin, P.H., Precioso, F., Philipp-Foliguet, S.

“…In content-based image retrieval context, a classic strategy consists in computing off-line a dictionary of visual features. This visual dictionary is then…”
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Population Pharmacokinetics and Pharmacodynamics of Burosumab in Adult and Pediatric Patients With X‐linked Hypophosphatemia by Lee, Sun Ku, Gosselin, Nathalie H., Taylor, Julie, Roberts, Mary Scott, McKeever, Kathleen, Shi, Jack

“…Burosumab is a fully human monoclonal antibody against fibroblast growth factor 23, which has been approved to treat X‐linked hypophosphatemia (XLH) in adult…”
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A Toxicokinetic Model of Malathion and Its Metabolites as a Tool to Assess Human Exposure and Risk through Measurements of Urinary Biomarkers by Bouchard, Michèle, Gosselin, Nathalie H., Brunet, Robert C., Samuel, Onil, Dumoulin, Marie-Josée, Carrier, Gaétan

“…A toxicokinetic model is proposed to predict the time evolution of malathion and its metabolites, mono- and dicarboxylic acids (MCA, DCA) and phosphoric…”
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Population pharmacokinetics and exposure-response relationships of maribavir in transplant recipients with cytomegalovirus infection by Song, Ivy H, Chen, Grace, Hayes, Siobhan, Farrell, Colm, Jomphe, Claudia, Gosselin, Nathalie H, Sun, Kefeng

“…Maribavir is approved for management of post-transplant cytomegalovirus (CMV) infections refractory and/or resistant to CMV therapies at a dose of 400 mg twice…”
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Exposure-Response Analyses of Lanadelumab in Patients with Hereditary Angioedema by Wang, Yi, Marier, Jean-Francois, Kassir, Nastya, Gosselin, Nathalie H., Martin, Patrick

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Model‐Informed Approach to Recommend Burosumab Dosing Regimens for Pediatric and Adult Patients With the Ultrarare Disease Tumor‐Induced Osteomalacia by Hruska, Matthew W., Sid‐Otmane, Lamia, Gosselin, Nathalie H., Quattrocchi, Emilia, Lee, Sun Ku, Mascelli, Mary Ann, Mehta, Krina, Jan de Beur, Suzanne M., Marsteller, Douglas

“…Burosumab is approved for the treatment of hypophosphatemia in persistent tumor‐induced osteomalacia. This work exemplifies a model‐informed drug development…”
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Estimating potential cardiovascular health benefits of improved population level control of LDL cholesterol through a twice-yearly siRNA-based approach: A simulation study of a health-system level intervention by Ray, Kausik K., Gunn, Laura H., Conde, Lorena Garcia, Raal, Frederick J., Wright, R. Scott, Gosselin, Nathalie H., Leiter, Lawrence A., Koenig, Wolfgang, Schwartz, Gregory G., Landmesser, Ulf

“…Inclisiran, an siRNA therapy, consistently reduces low-density lipoprotein cholesterol (LDL-C) with twice-yearly dosing. Potential cardiovascular benefits of…”
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Pan‐Arctic soil moisture control on tundra carbon sequestration and plant productivity by Zona, Donatella, Lafleur, Peter M., Hufkens, Koen, Gioli, Beniamino, Bailey, Barbara, Burba, George, Euskirchen, Eugénie S., Watts, Jennifer D., Arndt, Kyle A., Farina, Mary, Kimball, John S., Heimann, Martin, Göckede, Mathias, Pallandt, Martijn, Christensen, Torben R., Mastepanov, Mikhail, López‐Blanco, Efrén, Dolman, Albertus J., Commane, Roisin, Miller, Charles E., Hashemi, Josh, Kutzbach, Lars, Holl, David, Boike, Julia, Wille, Christian, Sachs, Torsten, Kalhori, Aram, Humphreys, Elyn R., Sonnentag, Oliver, Meyer, Gesa, Gosselin, Gabriel H., Marsh, Philip, Oechel, Walter C.

“…Long‐term atmospheric CO2 concentration records have suggested a reduction in the positive effect of warming on high‐latitude carbon uptake since the 1990s. A…”
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Reconstruction of methylmercury intakes in indigenous populations from biomarker data by Gosselin, Nathalie H, Brunet, Robert C, Carrier, Gaétan, Bouchard, Michèle, Feeley, Mark

“…Significant amounts of methylmercury (MeHg) can bioaccumulate in fish and sea mammals. To monitor MeHg exposure in individuals, organic and inorganic mercury…”
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Descriptor correlation analysis for remote sensing image multi-scale classification by dos Santos, J. A., Faria, F. A., da S Torres, R., Rocha, A., Gosselin, P-H, Philipp-Foliguet, S., Falcao, A.

“…This paper addresses the problem of remote sensing image multi-scale classification by: (i) showing that using multiple scales does improve classification…”
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Population Pharmacokinetics of Heptanoate in Healthy Subjects and Patients With Long‐Chain Fatty Acid Oxidation Disorders Treated With Triheptanoin by Lee, Sun Ku, Gosselin, Nathalie H., Jomphe, Claudia, McKeever, Kathleen, Putnam, Wendy

“…Triheptanoin is an odd‐carbon, medium‐chain triglyceride consisting of three fatty acids with seven carbons each on a glycerol backbone, indicated for the…”
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