Search Results - "Goss, J"

Antiviral drug discovery: preparing for the next pandemic by Adamson, Catherine S, Chibale, Kelly, Goss, Rebecca J M, Jaspars, Marcel, Newman, David J, Dorrington, Rosemary A

“…Clinically approved antiviral drugs are currently available for only 10 of the more than 220 viruses known to infect humans. The SARS-CoV-2 outbreak has…”
Get more information

Halogenases: a palette of emerging opportunities for synthetic biology-synthetic chemistry and C-H functionalisation by Crowe, Charlotte, Molyneux, Samuel, Sharma, Sunil V, Zhang, Ying, Gkotsi, Danai S, Connaris, Helen, Goss, Rebecca J M

“…The enzymatic generation of carbon-halogen bonds is a powerful strategy used by both nature and synthetic chemists to tune the bioactivity, bioavailability and…”
Get more information

Identification of the structure of the 3107 cm(-1) H-related defect in diamond by Goss, J P, Briddon, P R, Hill, V, Jones, R, Rayson, M J

“…A prominent hydrogen-related infrared absorption peak seen in many types of diamonds at 3107 cm(-1) has been the subject of investigation for many years. It is…”
Get more information

Antimicrobial nucleoside antibiotics targeting cell wall assembly: recent advances in structure-function studies and nucleoside biosynthesis by Winn, Michael, Goss, Rebecca J M, Kimura, Ken-ichi, Bugg, Timothy D H

“…The quest for new antibiotics, especially those with activity against Gram-negative bacteria, is urgent; however, very few new antibiotics have been marketed…”
Get more information

A single Streptomyces symbiont makes multiple antifungals to support the fungus farming ant Acromyrmex octospinosus by Seipke, Ryan F, Barke, Jörg, Brearley, Charles, Hill, Lionel, Yu, Douglas W, Goss, Rebecca J M, Hutchings, Matthew I

“…Attine ants are dependent on a cultivated fungus for food and use antibiotics produced by symbiotic Actinobacteria as weedkillers in their fungus gardens…”
Get full text

Dynamic landscape of protein occupancy across the Escherichia coli chromosome by Freddolino, Peter L, Amemiya, Haley M, Goss, Thomas J, Tavazoie, Saeed

“…Free-living bacteria adapt to environmental change by reprogramming gene expression through precise interactions of hundreds of DNA-binding proteins. A…”
Get full text

Gene Expression Enabling Synthetic Diversification of Natural Products: Chemogenetic Generation of Pacidamycin Analogs by Roy, Abhijeet Deb, Grüschow, Sabine, Cairns, Nickiwe, Goss, Rebecca J. M

“…Introduction of prnA, the halogenase gene from pyrrolnitrin biosynthesis, into Streptomyces coeruleorubidus resulted in efficient in situ chlorination of the…”
Get full text

High-Performance Low-Cost Electric Motor for Electric Vehicles Using Ferrite Magnets by Kimiabeigi, M., Widmer, J. D., Long, R., Gao, Y., Goss, J., Martin, R., Lisle, T., Soler Vizan, J. M., Michaelides, A., Mecrow, B.

“…Permanent-magnet motors with rare-earth magnets are among the best candidates for high-performance applications such as automotive applications. However, due…”
Get full text

Zelkovamycins B–E, Cyclic Octapeptides Containing Rare Amino Acid Residues from an Endophytic Kitasatospora sp by Hao, Xiaomeng, Yu, Jiaqing, Wang, Yujia, Connolly, Jack A, Liu, Yufeng, Zhang, Yuqin, Yu, Liyan, Cen, Shan, Goss, Rebecca J. M, Gan, Maoluo

“…Four unusual cyclopeptides, zelkovamycins B–E (1–4), were isolated from an endophytic Kitasatospora sp. Zelkovamycin B was featured by an unprecedented…”
Get full text

Correction: Dynamic landscape of protein occupancy across the Escherichia coli chromosome by Freddolino, Peter L, Amemiya, Haley M, Goss, Thomas J, Tavazoie, Saeed

“…[This corrects the article DOI: 10.1371/journal.pbio.3001306.]…”
Get full text

Impact of tillage system on arbuscular mycorrhiza fungal communities in the soil under Mediterranean conditions by Brito, Isabel, Goss, Michael J., de Carvalho, Mário, Chatagnier, Odile, van Tuinen, Diederik

“…► Effect of tillage system on arbuscular mycorrhiza fungi diversity based on DNA extract from soil. ► Nested PCR on the large ribosomal subunit (LSU rDNA) was…”
Get full text

Vitamin K Supplementation for the Prevention of Cardiovascular Disease: Where Is the Evidence? A Systematic Review of Controlled Trials by Vlasschaert, Caitlyn, Goss, Chloe J, Pilkey, Nathan G, McKeown, Sandra, Holden, Rachel M

“…Matrix gla protein (MGP) is an important vitamin K-dependent inhibitor of vascular calcification. High levels of uncarboxylated, dephosphorylated MGP have been…”
Get full text

Theory of Li in ZnO : A limitation for Li-based p-type doping by WARDLE, M. G, GOSS, J. P, BRIDDON, P. R

Get full text

The generation of "unnatural" products: synthetic biology meets synthetic chemistry by Goss, Rebecca J M, Shankar, Sreejith, Fayad, Antoine Abou

“…Natural product analogue generation is important, providing tools for chemical biology, enabling structure activity relationship determination and insight into…”
Get more information

First-principles study of the diffusion of hydrogen in ZnO by Wardle, M G, Goss, J P, Briddon, P R

“…Zinc oxide, a wide-gap semiconductor, typically exhibits n-type conductivity even when nominally undoped. The nature of the donor is contentious, but hydrogen…”
Get full text

Managing the functional diversity of arbuscular mycorrhizal fungi for the sustainable intensification of crop production by Brito, Isabel, Carvalho, Mário, Goss, Michael J.

“…Societal Impact Statement The need to increase food production with reduced use of resources and environmental impact demands innovative rethinking and…”
Get full text

Artificially oxygenating the Swan River estuary increases dissolved oxygen concentrations in the water and at the sediment interface by Larsen, Sarah J., Kilminster, Kieryn L., Mantovanelli, Alessandra, Goss, Zoë J., Evans, Georgina C., Bryant, Lee D., McGinnis, Daniel F.

“…•Artificial oxygenation increased oxygen concentrations in the shallow Swan River estuary.•Volume-averaged dissolved oxygen concentrations increased by…”
Get full text

Living GenoChemetics by hyphenating synthetic biology and synthetic chemistry in vivo by Sharma, Sunil V., Tong, Xiaoxue, Pubill-Ulldemolins, Cristina, Cartmell, Christopher, Bogosyan, Emma J. A., Rackham, Emma J., Marelli, Enrico, Hamed, Refaat B., Goss, Rebecca J. M.

“…Marrying synthetic biology with synthetic chemistry provides a powerful approach toward natural product diversification, combining the best of both worlds:…”
Get full text

The saponins: polar isoprenoids with important and diverse biological activities by Osbourn, Anne, Goss, Rebecca J M, Field, Robert A

“…Saponins are polar molecules that consist of a triterpene or steroid aglycone with one or more sugar chains. They are one of the most numerous and diverse…”
Get more information

A mixed community of actinomycetes produce multiple antibiotics for the fungus farming ant Acromyrmex octospinosus by Barke, Jörg, Seipke, Ryan F, Grüschow, Sabine, Heavens, Darren, Drou, Nizar, Bibb, Mervyn J, Goss, Rebecca J M, Yu, Douglas W, Hutchings, Matthew I

“…Attine ants live in an intensely studied tripartite mutualism with the fungus Leucoagaricus gongylophorus, which provides food to the ants, and with…”
Get full text