Effect of isoflurane on hematologic variables in ferrets

Effects of isoflurane on the CBC in ferrets were studied. There was rapid decrease in all hematologic variables after induction of anesthesia. Percentage reductions in indices of the erythron (hematocrit, RBC count, hemoglobin concentration) exceeded those of plasma protein concentration and WBC cou...

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Bibliographic Details
Published in:	American journal of veterinary research Vol. 55; no. 10; p. 1479
Main Authors:	Marini, R P, Jackson, L R, Esteves, M I, Andrutis, K A, Goslant, C M, Fox, J G
Format:	Journal Article
Language:	English
Published:	United States 01-10-1994
Subjects:	Animals Erythrocyte Count - veterinary Erythrocyte Indices - veterinary Female Ferrets - blood Hematocrit - veterinary Isoflurane - pharmacology Leukocyte Count - veterinary
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Summary:	Effects of isoflurane on the CBC in ferrets were studied. There was rapid decrease in all hematologic variables after induction of anesthesia. Percentage reductions in indices of the erythron (hematocrit, RBC count, hemoglobin concentration) exceeded those of plasma protein concentration and WBC count at the first postinduction time point. There was little additional decrease in these variables for the duration of anesthesia. The values had partially recovered to preanesthetic baseline at 45 minutes after anesthesia. Although these alterations appear to be well tolerated in healthy ferrets, care should be exercised when subjecting anemic, geriatric, or debilitated ferrets to isoflurane-induced anesthesia.
ISSN:	0002-9645
DOI:	10.2460/ajvr.1994.55.10.1479