Search Results - "Goshima, Gohta"
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Growth and division mode plasticity is dependent on cell density in marine‐derived black yeasts
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-02-2022)“…The diversity and ecological contribution of the fungus kingdom in the marine environment remain understudied. A recent survey in the Atlantic (Woods Hole, MA,…”
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Rho of Plants GTPases and Cytoskeletal Elements Control Nuclear Positioning and Asymmetric Cell Division during Physcomitrella patens Branching
Published in Current biology (20-07-2020)“…Branching morphogenesis is a widely used mechanism for development [1, 2]. In plants, it is initiated by the emergence of a new growth axis, which is of…”
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Identification of a TPX2-like microtubule-associated protein in Drosophila
Published in PloS one (30-11-2011)“…Chromosome segregation during mitosis and meiosis relies on the spindle and the functions of numerous microtubule-associated proteins (MAPs). One of the…”
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Division site determination during asymmetric cell division in plants
Published in The Plant cell (24-05-2022)“…During development, both animals and plants exploit asymmetric cell division (ACD) to increase tissue complexity, a process that usually generates cells…”
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The KCH Kinesin Drives Nuclear Transport and Cytoskeletal Coalescence to Promote Tip Cell Growth in Physcomitrella patens
Published in The Plant cell (01-07-2018)“…Long-distance transport along microtubules (MTs) is critical for intracellular organization. In animals, antagonistic motor proteins kinesin (plus end…”
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Mitotic spindle formation in the absence of Polo kinase
Published in Proceedings of the National Academy of Sciences - PNAS (22-03-2022)“…SignificanceMitosis is an essential process in all eukaryotes, but paradoxically, genes required for mitosis vary among species. The essentiality of many…”
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Five factors can reconstitute all three phases of microtubule polymerization dynamics
Published in The Journal of cell biology (07-11-2016)“…Cytoplasmic microtubules (MTs) undergo growth, shrinkage, and pausing. However, how MT polymerization cycles are produced and spatiotemporally regulated at a…”
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Drosophila kinesin-8 stabilizes the kinetochore-microtubule interaction
Published in The Journal of cell biology (04-02-2019)“…Kinesin-8 is required for proper chromosome alignment in a variety of animal and yeast cell types. However, it is unclear how this motor protein family…”
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Microcephaly protein Asp focuses the minus ends of spindle microtubules at the pole and within the spindle
Published in The Journal of cell biology (07-12-2015)“…Depletion of Drosophila melanogaster Asp, an orthologue of microcephaly protein ASPM, causes spindle pole unfocusing during mitosis. However, it remains…”
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A versatile microfluidic device for highly inclined thin illumination microscopy in the moss Physcomitrella patens
Published in Scientific reports (23-10-2019)“…High-resolution microscopy is a valuable tool for studying cellular processes, such as signalling, membrane trafficking, or cytoskeleton remodelling. Several…”
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Control of mitotic spindle length
Published in Annual review of cell and developmental biology (10-11-2010)“…The mitotic spindle accurately segregates genetic instructions by moving chromosomes to spindle poles (anaphase A) and separating the poles (anaphase B) so…”
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Spindle motility skews division site determination during asymmetric cell division in Physcomitrella
Published in Nature communications (05-05-2022)“…Asymmetric cell division (ACD) underlies the development of multicellular organisms. In animal ACD, the cell division site is determined by active…”
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Kinesin-13 and Kinesin-8 Function during Cell Growth and Division in the Moss Physcomitrella patens
Published in The Plant cell (01-03-2020)“…Kinesin-13 and Kinesin-8 are well-known microtubule (MT) depolymerases that regulate MT length and chromosome movement in animal mitosis. While much is unknown…”
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Kinetochore protein depletion underlies cytokinesis failure and somatic polyploidization in the moss Physcomitrella patens
Published in eLife (05-03-2019)“…Lagging chromosome is a hallmark of aneuploidy arising from errors in the kinetochore-spindle attachment in animal cells. However, kinetochore components and…”
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Mitotic Spindle Assembly in Land Plants: Molecules and Mechanisms
Published in Biology (Basel, Switzerland) (25-01-2017)“…In textbooks, the mitotic spindles of plants are often described separately from those of animals. How do they differ at the molecular and mechanistic levels?…”
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Endogenous localizome identifies 43 mitotic kinesins in a plant cell
Published in Proceedings of the National Academy of Sciences - PNAS (18-03-2014)“…Kinesins are microtubule (MT)-based motor proteins that have been identified in every eukaryotic species. Intriguingly, land plants have more than 60 kinesins…”
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Functional central spindle assembly requires de novo microtubule generation in the interchromosomal region during anaphase
Published in The Journal of cell biology (18-10-2010)“…The central spindle forms between segregating chromosomes during anaphase and is required for cytokinesis. Although anaphase-specific bundling and…”
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Cell tip growth underlies injury response of marine macroalgae
Published in PloS one (17-03-2022)“…Regeneration is a widely observed phenomenon by which the integrity of an organism is recovered after damage. To date, studies on the molecular and cellular…”
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Human microcephaly ASPM protein is a spindle pole-focusing factor that functions redundantly with CDK5RAP2
Published in Journal of cell science (01-11-2017)“…Nonsense mutations in the gene have been most frequently identified among familial microcephaly patients. Depletion of the orthologue ( ) causes spindle pole…”
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