Search Results - "Goshayeshi, Armon"
-
1
880 Inhibition of AXL signaling with AB801 augments anti-tumor immune responses
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundAXL receptor tyrosine kinase (AXL) is overexpressed in a variety of tumors and correlates with poor prognosis in cancer patients. AXL is expressed in…”
Get full text
Journal Article -
2
Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D1
Published in Nature metabolism (13-04-2020)Get full text
Journal Article -
3
Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D1
Published in Nature metabolism (01-04-2020)“…Ageing impairs tissue repair. This defect is pronounced in skeletal muscle, whose regeneration by muscle stem cells (MuSCs) is robust in young-adult animals,…”
Get full text
Journal Article -
4
Tubastatin A maintains adult skeletal muscle stem cells in a quiescent state ex vivo and improves their engraftment ability in vivo
Published in Stem cell reports (11-01-2022)“…Adult skeletal muscle stem cells (MuSCs) are important for muscle regeneration and constitute a potential source of cell therapy. However, upon isolation,…”
Get full text
Journal Article -
5
Death-seq identifies regulators of cell death and senolytic therapies
Published in Cell metabolism (03-10-2023)“…Selectively ablating damaged cells is an evolving therapeutic approach for age-related disease. Current methods for genome-wide screens to identify genes whose…”
Get full text
Journal Article -
6
Depletion of SAM leading to loss of heterochromatin drives muscle stem cell ageing
Published in Nature metabolism (01-01-2024)“…The global loss of heterochromatin during ageing has been observed in eukaryotes from yeast to humans, and this has been proposed as one of the causes of…”
Get full text
Journal Article -
7
Abstract 518: AB801 is a highly potent and selective AXL kinase inhibitor that demonstrates significant anti-tumor activity
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Background: AXL receptor tyrosine kinase (AXL) is overexpressed in a variety of tumors and correlates with poor prognosis in cancer patients. AXL is expressed…”
Get full text
Journal Article