Search Results - "Gorsline, Jane"

Illicit gamma-hydroxybutyrate (GHB) and pharmaceutical sodium oxybate (Xyrem® ): Differences in characteristics and misuse by Carter, Lawrence P, Pardi, Daniel, Gorsline, Jane, Griffiths, Roland R

“…Abstract There are distinct differences in the accessibility, purity, dosing, and misuse associated with illicit gamma-hydroxybutyrate (GHB) compared to…”
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Steady-state pharmacokinetics and dose relationship of nicotine delivered from Nicoderm (Nicotine Transdermal System) by Gorsline, J, Gupta, S K, Dye, D, Rolf, C N

“…An open-label, randomized, crossover study determined nicotine pharmacokinetics at steady state of a new Nicotine Transdermal System in 24 healthy adult male…”
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Comparison of the nicotine pharmacokinetics of Nicoderm (nicotine transdermal system) and half-hourly cigarette smoking by Gupta, S K, Hwang, S S, Causey, D, Rolf, C N, Gorsline, J

“…Nicoderm, a nicotine transdermal system (NTS), provides a continuous, transdermal delivery of nicotine and is used as an aid to smoking cessation. In contrast,…”
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Review: Illicit Gamma-Hydroxybutyrate (GHB) and Pharmaceutical Sodium Oxybate (Xyrem): Differences in Characteristics and Misuse by Carter, Lawrence P, Pardi, Daniel, Gorsline, Jane, Griffiths, Roland R

“…There are distinct differences in the accessibility, purity, dosing, and misuse associated with illicit gamma-hydroxybutyrate (GHB) compared to pharmaceutical…”
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Real-world efficacy of prescription and over-the-counter nicotine replacement therapy by Shiffman, Saul, Rolf, Clyde N., Hellebusch, Stephen J., Gorsline, Jane, Gorodetzky, Charles W., Chiang, Yu-Kun, Schleusener, Debra S., Marino, Michael E. Di

“…ABSTRACT Aims To assess smoking cessation rates achieved with nicotine gum and patch in simulated over‐the‐counter (OTC) and actual prescription (Rx) settings…”
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Efficacy of over-the-counter nicotine patch by Shiffman, Saul, Gorsline, Jane, Gorodetzky, Charles W.

“…This study aimed to assess the efficacy of the nicotine patch for smoking cessation, under simulated conditions of over-the-counter sale, absent any direct…”
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Triamcinolone acetonide 21-oic acid methyl ester: a potent local antiinflammatory steroid without detectable systemic effects by Gorsline, J, Bradlow, H L, Sherman, M R

“…There have been many previous attempts to prepare glucocorticoid analogs that would have high antiinflammatory activity at the site of application but minimal…”
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Avian endocrine responses to environmental pollutants by Rattner, B A, Eroschenko, V P, Fox, G A, Fry, D M, Gorsline, J

“…Many environmental contaminants are hazardous to populations of wild birds. Chlorinated hydrocarbon pesticides and industrial pollutants are thought to be…”
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In vitro and in vivo evaluation of a once-daily controlled-release pseudoephedrine product by Hwang, S S, Gorsline, J, Louie, J, Dye, D, Guinta, D, Hamel, L

“…The functionality of a once-daily, osmotic dosage form--gastrointestinal therapeutic system (pseudoephedrine HCl) or GITS (PeHCl)--was studied in vitro and in…”
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Comparison of the pharmacokinetics of two nicotine transdermal systems: nicoderm and habitrol by Gupta, S K, Okerholm, R A, Eller, M, Wei, G, Rolf, C N, Gorsline, J

“…This randomized, crossover study compared the nicotine and cotinine pharmacokinetic parameters and plasma concentration profiles of two different nicotine…”
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Absorption and adverse effects following topical and oral administration of three transdermal nicotine products to dogs by Matsushima, D, Prevo, M E, Gorsline, J

“…To evaluate potential adverse effects from inadvertent exposure to a nicotine transdermal system or "patch", three marketed products were administered…”
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Nicotine pharmacokinetics of Nicoderm (nicotine transdermal system) in women and obese men compared with normal-sized men by Prather, R D, Tu, T G, Rolf, C N, Gorsline, J

“…This study examined the effect of gender and body weight on the pharmacokinetic properties of the Nicotine Transdermal System (NTS) (Nicoderm). This NTS was…”
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Single- and multiple-dose pharmacokinetics of Nicoderm (Nicotine Transdermal System) by Gupta, S K, Okerholm, R A, Coen, P, Prather, R D, Gorsline, J

“…The pharmacokinetics and tolerability of single and multiple applications of Nicotine Transdermal Systems (NTS), designed to deliver 14 mg of nicotine per 24…”
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Comparison of plasma nicotine concentrations after application of nicoderm (nicotine transdermal system) to different skin sites by Gorsline, J, Okerholm, R A, Rolf, C N, Moos, C D, Hwang, S S

“…Drug absorption through the skin can vary according to the application site. The nicotine transdermal system, Nicoderm (Alza Corp., Palo Alto, CA) contains a…”
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Effects of adrenalectomy and spironolactone on urinary metabolites of aldosterone in rats by Gorsline, J, Morris, D J

“…The quantities and temporal sequences of appearance of aldosterone metabolites in the urine of adrenalectomized rats, and adrenalectomized rats treated with…”
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The hypertensinogenic activity of 19-nor-deoxycorticosterone in the adrenalectomized spontaneously hypertensive rat by Gorsline, J, Morris, D J

“…Infusions of 10 or 25 micrograms/day 19-nor-DOC for 2 weeks in adrenalectomized spontaneously hypertensive rats led to significant increases in blood pressure,…”
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Hypertensinogenic Activities of Ring A-Reduced Metabolites of Aldosterone by GORSLINE, JANE, HARNIK, MARCEL, TRESCO, PATRICK A, MORRIS, DAVID J

“…Spontaneously hypertensive rats (SHR) were adrenalectomized at 6 weeks of age and received subcutaneous implants of mini-osmotic pumps, loaded with vehicle…”
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The effects of 19-nor-aldosterone on blood pressure of adrenalectomized spontaneously hypertensive rats by Morris, D J, Gorsline, J, Tresco, P A, Harnik, M

“…The relative hypertensinogenic potencies of recently synthesized 19-nor-aldosterone and its precursor 19-OH-aldosterone were assessed in comparison to that of…”
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