Search Results - "Gorski, David H"

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    Trends in Metastatic Breast and Prostate Cancer — Lessons in Cancer Dynamics by Welch, H. Gilbert, Gorski, David H, Albertsen, Peter C

    Published in The New England journal of medicine (29-10-2015)
    “…Discordant trends in the incidence of metastatic breast and prostate cancer since the widespread implementation of early-detection efforts may reflect distinct…”
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    Metabotropic glutamate receptor-1: a potential therapeutic target for the treatment of breast cancer by Speyer, Cecilia L., Smith, Jennifer S., Banda, Malathi, DeVries, John A., Mekani, Tassia, Gorski, David H.

    Published in Breast cancer research and treatment (01-04-2012)
    “…Metabotropic glutamate receptors are G-protein-coupled receptors normally expressed in the central nervous system where they mediate neuronal excitability,…”
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    Metabotropic glutamate receptor-1 as a novel target for the antiangiogenic treatment of breast cancer by Speyer, Cecilia L, Hachem, Ali H, Assi, Ali A, Johnson, Jennifer S, DeVries, John A, Gorski, David H

    Published in PloS one (14-03-2014)
    “…Metabotropic glutamate receptors (mGluRs) are normally expressed in the central nervous system, where they mediate neuronal excitability and neurotransmitter…”
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    Regulation of the Expression and Activity of the Antiangiogenic Homeobox Gene GAX/MEOX2 by ZEB2 and MicroRNA-221 by Chen, Yun, Banda, Malathi, Speyer, Cecilia L., Smith, Jennifer S., Rabson, Arnold B., Gorski, David H.

    Published in Molecular and Cellular Biology (01-08-2010)
    “…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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    Metabotropic glutamate receptor-1 contributes to progression in triple negative breast cancer by Banda, Malathi, Speyer, Cecilia L, Semma, Sara N, Osuala, Kingsley O, Kounalakis, Nicole, Torres Torres, Keila E, Barnard, Nicola J, Kim, Hyunjin J, Sloane, Bonnie F, Miller, Fred R, Goydos, James S, Gorski, David H

    Published in PloS one (03-01-2014)
    “…TNBC is an aggressive breast cancer subtype that does not express hormone receptors (estrogen and progesterone receptors, ER and PR) or amplified human…”
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    Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5 by Chen, Yun, Gorski, David H.

    Published in Blood (01-02-2008)
    “…Angiogenesis is critical to tumor progression. The homeobox gene GAX inhibits angiogenesis in vascular endothelial cells (ECs). We have identified a microRNA…”
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    Integrative oncology: really the best of both worlds? by Gorski, David H.

    Published in Nature reviews. Cancer (01-10-2014)
    “…'Integrative oncology', also known as complementary and alternative medicine (CAM), is being increasingly accepted in cancer care and research. This Opinion…”
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    Infertility: A common target of antivaccine misinformation campaigns by Smith, Tara C., Gorski, David H.

    Published in Vaccine (06-02-2024)
    “…Misinformation, disinformation, and conspiracy theories about vaccines are key drivers of vaccine hesitancy. A repeated false claim about COVID-19 vaccines is…”
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    Combined effects of angiostatin and ionizing radiation in antitumour therapy by Weichselbaum, Ralph R, Mauceri, Helena J, Hanna, Nader N, Beckett, Michael A, Gorski, David H, Staba, Mary-Jane, Stellato, Kerri Anne, Bigelow, Kevin, Heimann, Ruth, Gately, Stephen, Dhanabal, Mohanraj, Soff, Gerald A, Sukhatme, Vikas P, Kufe, Donald W

    Published in Nature (London) (16-07-1998)
    “…Angiogenesis, the formation of new capillaries from pre-existing vessels, is essential for tumour progression. Angiostatin, a proteolytic fragment of…”
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    Vascular Endothelial Growth Factor C mRNA Expression Correlates with Stage of Progression in Patients with Melanoma by GOYDOS, James S, GORSKI, David H

    Published in Clinical cancer research (01-12-2003)
    “…Purpose: Vascular endothelial growth factor (VEGF)-C promotes the ingrowth and invasion of lymphatics in many different tumor types, including melanoma. To…”
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    Detection of B-RAF and N-RAS mutations in human melanoma by Goydos, James S., Mann, Barbara, Kim, Hyunjin J., Gabriel, Emmanuel M., Alsina, Janivette, Germino, F. Joseph, Shih, Weichung, Gorski, David H.

    “…It is now known that activating point mutations in components of the mitogen-activated protein kinase pathway commonly occur in melanoma. We previously…”
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    The Role of Homeobox Genes in Vascular Remodeling and Angiogenesis by Gorski, David H, Walsh, Kenneth

    Published in Circulation research (10-11-2000)
    “…Homeodomain-containing transcription factors are critical in the regulation of cell proliferation, differentiation, and migration, and they play an important…”
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    PDGFRα and β play critical roles in mediating Foxq1-driven breast cancer stemness and chemoresistance by Meng, Fanyan, Speyer, Cecilia L, Zhang, Bin, Zhao, Yongzhong, Chen, Wei, Gorski, David H, Miller, Fred R, Wu, Guojun

    Published in Cancer research (Chicago, Ill.) (01-02-2015)
    “…Many epithelial-mesenchymal transition (EMT)-promoting transcription factors have been implicated in tumorigenesis and metastasis as well as chemoresistance of…”
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    Inhibition of endothelial cell activation by the homeobox gene Gax by Gorski, David H, Leal, Alejandro J

    Published in The Journal of surgical research (01-05-2003)
    “…Background. Angiogenesis is critical to tumor growth. Gax, a homeobox transcription factor whose expression in the adult is restricted mainly to the…”
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    Impact of cross-reactivity and herd immunity on SARS-CoV-2 pandemic severity by Owusu-Boaitey, Nana, Böttcher, Lucas, He, Daihai, Erkhembayar, Ryenchindorj, Yang, Lin, Kim, Dong-Hyun, Barchuk, Anton, Gorski, David H, Howard, Jonathan

    Published in Infectious diseases (London, England) (02-10-2024)
    “…Public health systems reported low mortality from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in East Asia, in low-income countries, and for…”
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    Differential expression of vascular endothelial growth factor–A isoforms at different stages of melanoma progression by Gorski, David H, Leal, Alejandro D, Goydos, James S

    “…Vascular endothelial growth factor-A (VEGF-A) is an important mediator of angiogenesis in normal and neoplastic tissues. Total VEGF-A levels have been…”
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