Search Results - "Gorski, David H"
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Trends in Metastatic Breast and Prostate Cancer — Lessons in Cancer Dynamics
Published in The New England journal of medicine (29-10-2015)“…Discordant trends in the incidence of metastatic breast and prostate cancer since the widespread implementation of early-detection efforts may reflect distinct…”
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Metabotropic glutamate receptor-1: a potential therapeutic target for the treatment of breast cancer
Published in Breast cancer research and treatment (01-04-2012)“…Metabotropic glutamate receptors are G-protein-coupled receptors normally expressed in the central nervous system where they mediate neuronal excitability,…”
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Metabotropic glutamate receptor-1 as a novel target for the antiangiogenic treatment of breast cancer
Published in PloS one (14-03-2014)“…Metabotropic glutamate receptors (mGluRs) are normally expressed in the central nervous system, where they mediate neuronal excitability and neurotransmitter…”
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Regulation of the Expression and Activity of the Antiangiogenic Homeobox Gene GAX/MEOX2 by ZEB2 and MicroRNA-221
Published in Molecular and Cellular Biology (01-08-2010)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Metabotropic glutamate receptor-1 contributes to progression in triple negative breast cancer
Published in PloS one (03-01-2014)“…TNBC is an aggressive breast cancer subtype that does not express hormone receptors (estrogen and progesterone receptors, ER and PR) or amplified human…”
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Short-term changes in ultrasound tomography measures of breast density and treatment-associated endocrine symptoms after tamoxifen therapy
Published in NPJ breast cancer (15-03-2023)“…Although breast density decline with tamoxifen therapy is associated with greater therapeutic benefit, limited data suggest that endocrine symptoms may also be…”
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Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5
Published in Blood (01-02-2008)“…Angiogenesis is critical to tumor progression. The homeobox gene GAX inhibits angiogenesis in vascular endothelial cells (ECs). We have identified a microRNA…”
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Integrative oncology: really the best of both worlds?
Published in Nature reviews. Cancer (01-10-2014)“…'Integrative oncology', also known as complementary and alternative medicine (CAM), is being increasingly accepted in cancer care and research. This Opinion…”
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Infertility: A common target of antivaccine misinformation campaigns
Published in Vaccine (06-02-2024)“…Misinformation, disinformation, and conspiracy theories about vaccines are key drivers of vaccine hesitancy. A repeated false claim about COVID-19 vaccines is…”
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Combined effects of angiostatin and ionizing radiation in antitumour therapy
Published in Nature (London) (16-07-1998)“…Angiogenesis, the formation of new capillaries from pre-existing vessels, is essential for tumour progression. Angiostatin, a proteolytic fragment of…”
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Vascular Endothelial Growth Factor C mRNA Expression Correlates with Stage of Progression in Patients with Melanoma
Published in Clinical cancer research (01-12-2003)“…Purpose: Vascular endothelial growth factor (VEGF)-C promotes the ingrowth and invasion of lymphatics in many different tumor types, including melanoma. To…”
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Detection of B-RAF and N-RAS mutations in human melanoma
Published in Journal of the American College of Surgeons (01-03-2005)“…It is now known that activating point mutations in components of the mitogen-activated protein kinase pathway commonly occur in melanoma. We previously…”
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The Role of Homeobox Genes in Vascular Remodeling and Angiogenesis
Published in Circulation research (10-11-2000)“…Homeodomain-containing transcription factors are critical in the regulation of cell proliferation, differentiation, and migration, and they play an important…”
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PDGFRα and β play critical roles in mediating Foxq1-driven breast cancer stemness and chemoresistance
Published in Cancer research (Chicago, Ill.) (01-02-2015)“…Many epithelial-mesenchymal transition (EMT)-promoting transcription factors have been implicated in tumorigenesis and metastasis as well as chemoresistance of…”
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Inhibition of endothelial cell activation by the homeobox gene Gax
Published in The Journal of surgical research (01-05-2003)“…Background. Angiogenesis is critical to tumor growth. Gax, a homeobox transcription factor whose expression in the adult is restricted mainly to the…”
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Impact of cross-reactivity and herd immunity on SARS-CoV-2 pandemic severity
Published in Infectious diseases (London, England) (02-10-2024)“…Public health systems reported low mortality from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in East Asia, in low-income countries, and for…”
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The role of academic health centres to inform evidence-based integrative oncology practice
Published in Nature reviews. Cancer (01-04-2015)Get full text
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Author reply: the role of academic health centres to inform evidence-based integrative oncology practice
Published in Nature reviews. Cancer (01-04-2015)Get full text
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Differential expression of vascular endothelial growth factor–A isoforms at different stages of melanoma progression
Published in Journal of the American College of Surgeons (01-09-2003)“…Vascular endothelial growth factor-A (VEGF-A) is an important mediator of angiogenesis in normal and neoplastic tissues. Total VEGF-A levels have been…”
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Author reply: integrative oncology--strong science is needed for better patient care
Published in Nature reviews. Cancer (01-03-2015)Get full text
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