Search Results - "Gorringe, A"

Lethal and sublethal impacts of membrane-fed ivermectin are concentration dependent in Anopheles coluzzii by Shepherd-Gorringe, Monique A M, Pettit, Marie W, Hawkes, Frances M

“…Ivermectin is a well-tolerated anthelminthic drug with wide clinical and veterinary applications. It also has lethal and sublethal effects on mosquitoes. Mass…”
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Risk factors for Group B Streptococcus colonisation and disease in Gambian women and their infants by Le Doare, K, Jarju, S, Darboe, S, Warburton, F, Gorringe, A, Heath, P.T, Kampmann, B

“…Summary Objectives To determine risk factors for GBS colonisation in Gambian mothers and in their infants from birth to day 60–89 of age. Methods Swabs and…”
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Experimental disease models for the assessment of meningococcal vaccines by Gorringe, A.R., Reddin, K.M., Funnell, S.G., Johansson, L., Rytkönen, A., Jonsson, A.-B.

“…Animal infection models are valuable for the development and preclinical assessment of meningococcal vaccines in the absence of clear in vitro correlates of…”
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Induction of immune responses by purified outer membrane protein complexes from Neisseria meningitidis by Marzoa, J, Sánchez, S, Costoya, L, Diéguez-Casal, E, Freixeiro, P, Brookes, C, Allen, L, Taylor, S, Gorringe, A.R, Ferreirós, C.M, Criado, M.T

“…Highlights ► We analyse immune responses elicited by meningococcal outer membrane complexes. ► Chaperonin and PorA/PorB/RmpM complexes induce the best immune…”
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Infection with an Avirulent phoP Mutant of Neisseria meningitidis Confers Broad Cross-Reactive Immunity by NEWCOMBE, J, EALES-REYNOLDS, L.-J, WOOTTON, L, GORRINGE, A. R, FUNNELL, S. G. P, TAYLOR, S. C, MCFADDEN, J. J

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Recombinant Neisseria meningitidis Transferrin Binding Protein A Protects against Experimental Meningococcal Infection by WEST, David, REDDIN, Karen, MATHESON, Mary, HEATH, Robert, FUNNELL, Simon, HUDSON, Michael, ROBINSON, Andrew, GORRINGE, Andrew

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Generation and characterization of a PhoP homologue mutant of Neisseria meningitidis by Johnson, C. R., Newcombe, J., Thorne, S., Borde, H. A., Eales‐Reynolds, L.‐J., Gorringe, A. R., Funnell, S. G. P., McFadden, J. J.

“…Two‐component regulatory systems are important regulators of virulence genes in a number of bacteria. Genes encoding a two‐component regulator system, with…”
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Periplasmic Superoxide Dismutase in Meningococcal Pathogenicity by WILKS, K. E, DUNN, K. L. R, FARRANT, J. L, REDDIN, K. M, GORRINGE, A. R, LANGFORD, P. R, KROLL, J. S

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The plug domain of a neisserial TonB-dependent transporter retains structural integrity in the absence of its transmembrane β-barrel by Oke, M, Sarra, R, Ghirlando, R, Farnaud, S, Gorringe, A.R, Evans, R.W, Buchanan, S.K

“…Transferrin binding protein A (TbpA) is a TonB-dependent outer membrane protein expressed by pathogenic bacteria for iron acquisition from human transferrin…”
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Pilot study of human experimental challenge with neisseria lactamica by Evans, C, Gorringe, A, Matheson, M, Pratt, C, Borrow, R, Findlow, J, Read, R.C

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Immune responses in humans and animals to meningococcal transferrin-binding proteins: implications for vaccine design by ALA'ALDEEN, D. A. A, STEVENSON, P, GRIFFITHS, E, GORRINGE, A. R, IRONS, L. I, ROBINSON, A, HYDE, S, BORRIELLO, S. P

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Human Opsonins Induced during Meningococcal Disease Recognize Transferrin Binding Protein Complexes by LEHMANN, A. K, GORRINGE, A. R, REDDIN, K. M, WEST, K, SMITH, I, HALSTENSEN, A

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Neisseria lactamica Protects against Experimental Meningococcal Infection by OLIVER, Kerry J, REDDIN, Karen M, BRACEGIRDLE, Philippa, HUDSON, Michael J, BORROW, Ray, FEAVERS, Ian M, ROBINSON, Andrew, CARTWRIGHT, Keith, GORRINGE, Andrew R

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A Dynamic Model of the Meningococcal Transferrin Receptor by Boulton, I.C, Gorringe, A.R, Shergill, J.K, Joannou, C.L, Evans, R.W

“…Iron is an essential nutrient for all organisms and consequently, the ability to bind transferrin and sequester iron from his source constitutes a distinct…”
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Human antibody response to meningococcal transferrin binding proteins: evidence for vaccine potential by Gorringe, Andrew R., Borrow, Ray, Fox, Andrew J., Robinson, Andrew

“…During iron-limited growth Neisseria meningitidis expresses two transferrin binding proteins, TBP1 and TBP2, with molecular masses of approximately 98 and…”
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Demonstration of lipooligosaccharide immunotype and capsule as virulence factors for Neisseria meningitidis using an infant mouse intranasal infection model by Mackinnon, F G, Borrow, R, Gorringe, A R, Fox, A J, Jones, D M, Robinson, A

“…Using an infant mouse intranasal infection model, we have compared the virulence of 17 epidemiologically related isolates of Neisseria meningitidis associated…”
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Differential binding of apo and holo human transferrin to meningococci and co-localisation of the transferrin-binding proteins (TbpA and TbpB) by Powell, N. B. L, Bishop, K, Palmer, H. M, Ala'Aldeen, D. A, Gorringe, A. R, Borriello, S. P

“…* Microbial Pathogenicity Research Group, Division of Microbiology and Institute of Infections and Immunity, Queen's Medical Centre, Nottingham NG7 2UH Centre…”
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Characterisation of the meningococcal transferrin binding protein complex by photon correlation spectroscopy by Boulton, I.C., Gorringe, A.R., Carr, R.J.G., Gorinsky, B., Joannou, Christopher L., Evans, R.W.

“…Photon correlation spectroscopy demonstrated for the first time that co-purified meningococcal TbpA+B form a complex in solution. This structure bound hTf and…”
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Serospecific protection of mice against intranasal infection with Bordetella pertussis by Robinson, A, Gorringe, A R, Funnell, S G, Fernandez, M

“…The ability of purified serospecific agglutinogens from Bordetella pertussis to protect mice against intranasal infection has been examined. Immunization with…”
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Transferrin-binding protein B isolated from Neisseria meningitidis discriminates between apo and diferric human transferrin by Boulton, I C, Gorringe, A R, Allison, N, Robinson, A, Gorinsky, B, Joannou, C L, Evans, R W

“…Neisseria meningitidis utilization of human serum transferrin (hTF)-bound iron is an important pathogenicity determinant. The efficiency of this system would…”
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