Search Results - "Gorres, Kelly L"
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Transcriptome analysis of Burkitt lymphoma cells treated with anti-convulsant drugs that are inhibitors of Epstein-Barr virus lytic reactivation
Published in PloS one (18-04-2024)“…Herpesviruses have two distinct life cycle stages, latency and lytic replication. Epstein-Barr virus (EBV), a gamma-herpesvirus, establishes latency in vivo…”
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Activation and repression of Epstein-Barr Virus and Kaposi's sarcoma-associated herpesvirus lytic cycles by short- and medium-chain fatty acids
Published in Journal of virology (01-07-2014)“…The lytic cycles of Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV) are induced in cell culture by sodium butyrate (NaB), a…”
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Inhibition of Epstein-Barr Virus Lytic Reactivation by the Atypical Antipsychotic Drug Clozapine
Published in Viruses (17-05-2019)“…Epstein-Barr virus (EBV), a member of the family, maintains a lifelong latent infection in human B cells. Switching from the latent to the lytic phase of its…”
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Valpromide Inhibits Lytic Cycle Reactivation of Epstein-Barr Virus
Published in mBio (01-03-2016)“…Reactivation of Epstein-Barr virus (EBV) from latency into the lytic phase of its life cycle allows the virus to spread among cells and between hosts. Valproic…”
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Prolyl 4-hydroxylase
Published in Critical reviews in biochemistry and molecular biology (01-04-2010)“…Posttranslational modifications can cause profound changes in protein function. Typically, these modifications are reversible, and thus provide a biochemical…”
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Stringency of the 2-His-1-Asp active-site motif in prolyl 4-hydroxylase
Published in PloS one (05-11-2009)“…The non-heme iron(II) dioxygenase family of enzymes contain a common 2-His-1-carboxylate iron-binding motif. These enzymes catalyze a wide variety of oxidative…”
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Mood stabilizers inhibit cytomegalovirus infection
Published in Virology (New York, N.Y.) (01-12-2016)“…Abstract Cytomegalovirus (CMV) infection can generate debilitating disease in immunocompromised individuals and neonates. It is also the most common infectious…”
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Conformational Preferences of Substrates for Human Prolyl 4-Hydroxylase
Published in Biochemistry (Easton) (09-09-2008)“…Prolyl 4-hydroxylase (P4H) catalyzes the posttranslational hydroxylation of (2S)-proline (Pro) residues in procollagen strands. The resulting…”
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Direct and continuous assay for prolyl 4-hydroxylase
Published in Analytical biochemistry (15-03-2009)“…Prolyl 4-hydroxylase (P4H) is a nonheme iron dioxygenase that catalyzes the posttranslational hydroxylation of (2 S)-proline (Pro) residues in protocollagen…”
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Structure and Function of Bacillus subtilis YphP, a Prokaryotic Disulfide Isomerase with a CXC Catalytic Motif
Published in Biochemistry (Easton) (15-09-2009)“…The DUF1094 family contains over 100 bacterial proteins, all containing a conserved CXC motif, with unknown function. We solved the crystal structure of the…”
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Substrate specificity and conformational preferences of prolyl 4‐hydroxylase
Published in The FASEB journal (01-03-2008)“…Abstract only Prolyl 4‐hydroxylase (P4H) catalyzes the post‐translational hydroxylation of proline residues in procollagen strands. P4H specifically forms 4( R…”
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Structure and Function of Bacillus subtilis YphP, a Prokaryotic Disulfide Isomerase with a CXC Catalytic Motif aNB super(,) a
Published in Biochemistry (Easton) (15-09-2009)“…The DUF1094 family contains over 100 bacterial proteins, all containing a conserved CXC motif, with unknown function. We solved the crystal structure of the…”
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