Search Results - "Gormley, N A"

Rapid single-colony whole-genome sequencing of bacterial pathogens by Köser, Claudio U, Fraser, Louise J, Ioannou, Avgousta, Becq, Jennifer, Ellington, Matthew J, Holden, Matthew T G, Reuter, Sandra, Török, M Estée, Bentley, Stephen D, Parkhill, Julian, Gormley, Niall A, Smith, Geoffrey P, Peacock, Sharon J

“…As a result of the introduction of rapid benchtop sequencers, the time required to subculture a bacterial pathogen to extract sufficient DNA for library…”
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Mode of action of GR122222X, a novel inhibitor of bacterial DNA gyrase by ORAM, M, BHUPINDER DOSANJH, GORMLEY, N. A, SMITH, C. V, FISHER, L. M, MAXWELL, A, DUNCAN, K

“…Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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Restriction endonuclease reactions requiring two recognition sites by Halford, S E, Bilcock, D T, Stanford, N P, Williams, S A, Milsom, S E, Gormley, N A, Watson, M A, Bath, A J, Embleton, M L, Gowers, D M, Daniels, L E, Parry, S H, Szczelkun, M D

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The Interaction of Coumarin Antibiotics with Fragments of the DNA Gyrase B Protein by Gormley, Niall A., Orphanides, George, Meyer, Andrew, Cullis, Paul M., Maxwell, Anthony

“…DNA gyrase is the target of the coumarin group of antibacterial agents. The drugs are known to inhibit the ATPase activity of gyrase and bind to the 24-kDa…”
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Probing the Binding of Coumarins and Cyclothialidines to DNA Gyrase by Kampranis, Sotirios C, Gormley, Niall A, Tranter, Rebecca, Orphanides, George, Maxwell, Anthony

“…DNA gyrase is the target of a number of antibacterial agents, including the coumarins and the cyclothialidines. To extend our understanding of the mechanism of…”
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Reactions of BglI and Other Type II Restriction Endonucleases with Discontinuous Recognition Sites by Gormley, Niall A., Bath, Abigail J., Halford, Stephen E.

“…Type II restriction enzymes generally recognize continuous sequences of 4–8 consecutive base pairs on DNA, but some recognize discontinuous sites where the…”
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Manganese(II) as a probe for the mechanism and specificity of restriction endonucleases by Baldwin, G S, Gormley, N A, Halford, S E

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Many Type IIs Restriction Endonucleases Interact with Two Recognition Sites before Cleaving DNA by Bath, Abigail J., Milsom, Susan E., Gormley, Niall A., Halford, Stephen E.

“…Type IIs restriction endonucleases recognize asymmetric DNA sequences and cleave both DNA strands at fixed positions, typically several base pairs away from…”
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The Type IIs Restriction Endonuclease BspMI Is a Tetramer That Acts Concertedly at Two Copies of an Asymmetric DNA Sequence by Gormley, Niall A., Hillberg, Anna L., Halford, Stephen E.

“…Type IIs endonucleases recognize asymmetric DNA sequences and cleave both strands at fixed positions downstream of the sequence. Many type IIs enzymes,…”
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DNA supercoiling enables the Type IIS restriction enzyme BspMI to recognise the relative orientation of two DNA sequences by Kingston, Isabel J., Gormley, Niall A., Halford, Stephen E.

“…Many proteins can sense the relative orientations of two sequences at distant locations in DNA: some require sites in inverted (head‐to‐head) orientation,…”
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